Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6 by André Fischer (5706887)

“…In this study, starting from the crystal structure, we built a full-length membrane-anchored all-atom model of the wild-type CYP2D6 as well as five of its variants differing in the enzymatic activity. …”

Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6 by André Fischer (5706887)

“…In this study, starting from the crystal structure, we built a full-length membrane-anchored all-atom model of the wild-type CYP2D6 as well as five of its variants differing in the enzymatic activity. …”

Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6 by André Fischer (5706887)

“…In this study, starting from the crystal structure, we built a full-length membrane-anchored all-atom model of the wild-type CYP2D6 as well as five of its variants differing in the enzymatic activity. …”

Input-scaled sorghum biomass C and N₂O emissions. by Benjamin D. Duval (415098)

“…Points are mean value and error bars are SEM for current weather simulations (a and c) or the range of simulation values across a suite of future weather inputs (b and d).…”

FSM^R GAPDH variants support robust catalytic efficiency but exhibit altered cooperativity. by Andrew J. Jezewski (8934521)

“…A statistically significant decrease in catalytic efficiency is measured for the GAPDH^V238A variant compared to WT. …”

Cytoskeleton and matrix remodeling during acute thymic atrophy. by Matthew J. Billard (227285)

“…A full legend of all GeneGo pathway map symbols is in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017940#pone.0017940.s009" target="_blank">Figure S9</a> or at <a href="http://www.genego.com/pdf/MC_legend.pdf" target="_blank">http://www.genego.com/pdf/MC_legend.pdf</a>.…”

Effect of HPBCD treatment in 7-week old male <i>Npc1</i>^<i>-/-</i> mice. by Elena-Raluca Nicoli (2577265)

Proteolytically Stable Diaza-Peptide Foldamers Mimic Helical Hot Spots of Protein–Protein Interactions and Act as Natural Chaperones by Chenghui Shi (6429962)

“…The ability of these foldamers to resist proteolysis, to mimic the small helical hot spot of transthyretin-amyloid β (Aβ) cross-interaction, and to decrease pathological Aβ aggregation demonstrates that the introduction of diaza-peptide units is a valid approach for designing mimics or inhibitors of protein–protein interaction and other therapeutic peptidomimetics. …”

Proteolytically Stable Diaza-Peptide Foldamers Mimic Helical Hot Spots of Protein–Protein Interactions and Act as Natural Chaperones by Chenghui Shi (6429962)

“…The ability of these foldamers to resist proteolysis, to mimic the small helical hot spot of transthyretin-amyloid β (Aβ) cross-interaction, and to decrease pathological Aβ aggregation demonstrates that the introduction of diaza-peptide units is a valid approach for designing mimics or inhibitors of protein–protein interaction and other therapeutic peptidomimetics. …”

Proteolytically Stable Diaza-Peptide Foldamers Mimic Helical Hot Spots of Protein–Protein Interactions and Act as Natural Chaperones by Chenghui Shi (6429962)

“…The ability of these foldamers to resist proteolysis, to mimic the small helical hot spot of transthyretin-amyloid β (Aβ) cross-interaction, and to decrease pathological Aβ aggregation demonstrates that the introduction of diaza-peptide units is a valid approach for designing mimics or inhibitors of protein–protein interaction and other therapeutic peptidomimetics. …”

Age-related trabecular bone loss in male TTD mice. by Claudia Nicolaije (172380)

“…(A) Trabecular bone volume fraction (BV/TV), (B) Endocortical volume (Ec.V.), (C) Trabecular number (Tb.N.), (D) Trabecular thickness (Tb.Th.). 100 cross-sections were measured in the metaphysis of TTD and wild type mice. …”

<i>Nipped-B</i> mutant wing discs show broadly reduced gene expression by RNA-seq analysis. by Yaning Wu (823030)

“…(B) Density distribution plots of the fold-changes in gene expression between <i>Nipped-B</i> mutants and the wild-type control (log2 <i>Nipped-B</i>^<i>407</i> / P57B ratio) for all genes (black) and those genes for which the change has a p value ≤ 0.05. …”

EFFECTIVENESS OF CHIROPRACTIC ADJUSTMENT IN LUMBAR PAIN IN CROSSFIT PRACTITIONERS by DESIREE MOEHLECKE (12812300)

Describing and diffusing the ethnobotanical knowledge of Bogotá D.C. (Colombia) through an online tool focused on common names of plants by Ángela Rodríguez-Calderón (7142123)

Identification of the potential inhibitors of malolactic fermentation in wines by Renata Vieira da MOTA (4651042)

Identification of the potential inhibitors of malolactic fermentation in wines by Renata Vieira da MOTA (4651042)

Postural responses of galvanic vestibular stimulation: comparison between groups of older adults and young people by Regiane Luz Carvalho (8618754)

Influence of transverse rebars on bond between steel reinforcement and cellular concrete with very low compressive strength by P. R. N. SOUDAIS (5528963)

Judicialization of medicines in the State of Rio de Janeiro: development from 2010 to 2017 by Letícia de Oliveira Peçanha (10395481)

Evaluation of Basic Education teachers’ graphic literacy at training and profesional action by Francisco Rodríguez-Alveal (5550914)