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point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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36001
Pa alleviated <i>D</i>-gal and AlCl<sub>3</sub>-induced Aβ and tau burdens in the hippocampus.
Published 2017“…Pa did not affect the expression of 16 KD Aβ oligomers (<b>F</b>); however, it decreased the expression of 28 KD Aβ oligomers after the treatment of Pa for 2 or 6 weeks (<b>G</b>), downregulated the expression of 36 KD Aβ oligomers after the treatment of Pa for 6 weeks (<b>H</b>), and reduced the expression of 56 KD Aβ oligomers after the treatment of Pa for 2 or 6 weeks (<b>I</b>). …”
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36002
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36003
Potent 5‑Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1–UBE2M Interaction
Published 2019“…After finding a novel inhibitor <b>DC-1</b> with IC<sub>50</sub> = 1.2 μM, we performed a series of chemical optimizations, which finally led to the discovery of a potent thiazole containing 5-cyano-6-phenylpyrimidin-based inhibitor <b>DC-2</b> (IC<sub>50</sub> = 15 nM). …”
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36004
<b><i>Uterine Artery Bulk RNA sequencing and transcriptomics</i></b> from non-pregnant wild type, <i>Rgs</i>2 KO, <i>Rgs5 </i>KO, and <i>Rgs2/5 </i>double knockout mice
Published 2024“…Previous studies showed that the loss of G<sub>i/o</sub> and G<sub>q/11</sub> regulation by RGS2 and RGS5 is involved in augmented vascular tone and decreased uterine blood flow in mice. …”
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36005
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36006
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36007
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36008
Low-dose 5-aza and DNMT3B knockdown alters genome-wide promoter demethylation in NT2/D1-R1 cells.
Published 2012“…The numbers represent methylation changes of 1.3-fold or greater with p<0.05. <b>Middle</b>, A moderate degree of overlap in genes in NT2/D1-R1 cells that underwent decreased DNA methylation and increased gene expression with 5-aza (left) and little overlap in genes in NT2/D1-R1 cells that underwent increased DNA methylation and increased gene expression with 5-aza. …”
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36009
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36010
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36011
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36012
Δ6 and Δ5 desaturases are active in rat aorta smooth muscle and are involved in human femoral artery vasoconstriction.
Published 2012“…<p>(A) and (B), rat aorta. Removal of the endothelium from male rat aorta did not alter inhibition of Pe-induced vasoconstriction by (A) Δ6 desaturase inhibitor SC26196 (10<sup>−4</sup> M) or (B) Δ5 desaturase inhibitor sesamin (10<sup>−4</sup> M). …”
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36013
Image_5_Play to Win: Action Video Game Experience and Attention Driven Perceptual Exploration in Categorization Learning.JPEG
Published 2020“…All stimuli had the same structure but differed with respect to their color combinations and were forming two categories including a prototype, five typical stimuli and one exception. …”
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36014
Image_5_Hypoxia Alters Epigenetic and N-Glycosylation Profiles of Ovarian and Breast Cancer Cell Lines in-vitro.TIF
Published 2020“…SiRNA transient knock down of GATA2/3 transcription factors resulted in a decrease in the expression of glycosyltransferases ST3GAL4 and MGAT5, which are responsible for sialylation and branching, respectively.…”
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36015
Table_2_Correlation Between Improved Mating Efficiency and Weakened Scaffold-Kinase Interaction in the Mating Pheromone Response Pathway Revealed by Interspecies Complementation.xl...
Published 2022“…Consistently, chimeric Ste5 displaying a higher affinity for Ste7 decreased the mating efficiency, while chimeric Ste5 displaying a lower affinity for Ste7 improved the mating efficiency. …”
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36016
Table 1_Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway.docx
Published 2025“…</p>Methods<p>Male C57BL/6 mice were assigned to groups and fed either a control diet or an HFD for 12 weeks, which was followed by a 3-week intervention with miR-144-5p. …”
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36017
MDA5 and TLR3 Initiate Pro-Inflammatory Signaling Pathways Leading to Rhinovirus-Induced Airways Inflammation and Hyperresponsiveness
Published 2011“…MDA5 null mice showed a delayed type I IFN and attenuated type III IFN response to RV1B infection, leading to a transient increase in viral titer. …”
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36018
Table_1_Correlation Between Improved Mating Efficiency and Weakened Scaffold-Kinase Interaction in the Mating Pheromone Response Pathway Revealed by Interspecies Complementation.xl...
Published 2022“…Consistently, chimeric Ste5 displaying a higher affinity for Ste7 decreased the mating efficiency, while chimeric Ste5 displaying a lower affinity for Ste7 improved the mating efficiency. …”
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36019
Data_Sheet_1_Correlation Between Improved Mating Efficiency and Weakened Scaffold-Kinase Interaction in the Mating Pheromone Response Pathway Revealed by Interspecies Complementati...
Published 2022“…Consistently, chimeric Ste5 displaying a higher affinity for Ste7 decreased the mating efficiency, while chimeric Ste5 displaying a lower affinity for Ste7 improved the mating efficiency. …”
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36020
Table 2_Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway.xlsx
Published 2025“…</p>Methods<p>Male C57BL/6 mice were assigned to groups and fed either a control diet or an HFD for 12 weeks, which was followed by a 3-week intervention with miR-144-5p. …”