Interleukin-1/Toll-Like Receptor-Induced Nuclear Factor Kappa B Signaling Participates in Intima Hyperplasia after Carotid Artery Balloon Injury in Goto-Kakizaki Rats: A Potential... by Xiaotian Zhang (529088)

“…The underlying mechanism of intima hyperplasia was investigated with a model of carotid balloon injury in Goto-Kakizaki (GK) and Wistar rats and with lipopolysaccharide-stimulated macrophages. …”

Data Sheet 6_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... by Shen Tian (4424170)

“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.…”

Data Sheet 3_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... by Shen Tian (4424170)

“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.…”

Data Sheet 1_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... by Shen Tian (4424170)

“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.…”

Data Sheet 2_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... by Shen Tian (4424170)

“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.…”

Data Sheet 1_Global, regional, and national burden of 34 cancer groups across 204 countries and territories, 1990–2021, and projections to 2050: a systematic analysis of the Global... by Linfeng Zhu (759210)

“…Cancer incidence has risen 2.3-fold, with the ASIR increasing by 8.8% and the ASMR decreasing by 21.5% over the period since 1990. Tracheal, bronchial, and lung cancer, colorectal cancer, stomach cancer, and breast cancer were the leading causes of mortality, while nonmelanoma skin cancer, tracheal, bronchial, and lung cancer, colorectal cancer, breast cancer, and prostate cancer had the highest incidence rates. …”

Data Sheet 2_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... by Junhong Yang (7807046)

“…Notably, the incidence of VVRs decreased with increasing donor age. Additionally, the estimated incidences of VVRs were higher among female donors (13.600%) and first-time donors (18.536%) compared to male donors (11.205%) or repeat donors (5.819%). …”

Data Sheet 1_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... by Junhong Yang (7807046)

“…Notably, the incidence of VVRs decreased with increasing donor age. Additionally, the estimated incidences of VVRs were higher among female donors (13.600%) and first-time donors (18.536%) compared to male donors (11.205%) or repeat donors (5.819%). …”

A parameter sweep of <i>β</i> (rate of transition from uninfected (U) to eclipse phase (I1) cells) from 0.01x to 100x baseline reveals steady growth increases. by Josua O. Aponte-Serrano (9904912)

“…Tracking of cell types (U, I1, virus releasing, I2, and dead, D) for plaque growth dynamics corresponding to plaques in A. Center lines represent median over 20 replicas; shaded areas are the 5^th and 95^th percentiles. …”

FIGURE 3 from PARP Inhibitors Effectively Reduce MAPK Inhibitor Resistant Melanoma Cell Growth and Synergize with MAPK Inhibitors through a Synthetic Lethal Interaction <i>In Vitro... by Lisa Marie Fröhlich (16838353)

“…<p>MAPKi resistant cells show decreased ATM expression. <b>A,</b> Immunoblot analysis of A375 R cells treated with 5 μmol/L talazoparib (Tala.) for 24 hours or untreated (Ctr.). …”

Image_1_Perioperative lidocaine and dexmedetomidine intravenous infusion reduce the serum levels of NETs and biomarkers of tumor metastasis in lung cancer patients: A prospective,... by Baiqing Ren (14675129)

“…The patients were equally randomized to a placebo group (Group C), a lidocaine group (Group L, intravenous lidocaine 8 mg/kg/h for 15 minutes before anesthesia, 2 mg/kg/h during surgery, and 1 mg/kg/h until 24 hours after surgery), a dexmedetomidine group (Group D, intravenous dexmedetomidine 2 μg/kg/h for 15 minutes before anesthesia, 0.5 μg/kg/h during surgery, and 0.25 μg/kg/h until 24 hours after surgery), and a dexmedetomidine plus lidocaine group (Group LD, combination use of lidocaine and dexmedetomidine). …”

DataSheet2_ADRB2 serves as a novel biomarker and attenuates alcoholic hepatitis via the SIRT1/PGC-1α/PPARα pathway: integration of WGCNA, machine learning and experimental validati... by Li Song (34475)

“…</p>Conclusion<p>This study points to ADRB2 as a promising biomarker with potential diagnostic and prognostic value in clinical cohort data. …”

DataSheet1_ADRB2 serves as a novel biomarker and attenuates alcoholic hepatitis via the SIRT1/PGC-1α/PPARα pathway: integration of WGCNA, machine learning and experimental validati... by Li Song (34475)

“…</p>Conclusion<p>This study points to ADRB2 as a promising biomarker with potential diagnostic and prognostic value in clinical cohort data. …”

Image1_A randomized, open-label, parallel pilot study investigating metabolic product kinetics of the novel ketone ester, bis-hexanoyl (R)-1,3-butanediol, over one week of ingestio... by Eunice Mah (5918042)

“…</p><p>Methods: We undertook a randomized, parallel, open-label study in healthy adults (n = 33) to elucidate blood BHB, HEX and BDO concentrations for 8 h following consumption of three different serving sizes (SS) of BH-BD (12.5, 25 and 50 g/day) before (Day 0) and after 7 days of daily BH-BD consumption (Day 7).…”

Relative change in catch for the last 20 years of projection for 50% increase in fishing effort of crustaceans (ICRUS50%), a 50% increase in fishing effort for crustaceans and finf... by Javier Porobic (6392612)

“…Note that the y-axes is the ratio of change against the starting conditions—so a -0.5 result indicates a 50% decrease and a 0.5 result indicates a 50% increase -.…”

DataSheet_1_Free Versus Fixed-Ratio Combination of Basal Insulin and GLP-1 Receptor Agonists in Type 2 Diabetes Uncontrolled With GLP-1 Receptor Agonists: A Systematic Review and I... by Han Na Jung (9942484)

“…Both approaches significantly lowered HbA1c levels (weighted mean difference [WMD] −0.75%, 95% CI −0.97 to −0.53) but increased hypoglycemic risk [risk ratio (RR) 7.59, 95% CI 3.35−17.17] compared to the unchanged GLP-1RA. …”

Figure S1 - A Prolyl-Hydroxylase Inhibitor, Ethyl-3,4-Dihydroxybenzoate, Induces Cell Autophagy and Apoptosis in Esophageal Squamous Cell Carcinoma Cells via Up-Regulation of BNIP3... by Bo Han (84102)

“…<p><b>Gene expression profile analysis of EDHB-treated KYSE 170 cells.</b> (A) Heat map of overlapping genes. Red/green indicate an increase/decrease in gene expression relative to the universal mean for each gene. …”

S1 File - by Berhan Tekeba (15353895)

“…We included a total weighted sample of 74,871 reproductive-aged women who gave birth in the five years preceding the survey. …”

<i>skn-1b</i> is not required for WT or <i>daf-2</i> longevity A-F) Survival of WT and <i>skn-1b</i> mutants in the absence and presence of <i>daf-2</i> mutation. by Nikolaos Tataridas-Pallas (10231350)

“…We conclude that <i>skn-1b</i> does not contribute to <i>daf-2</i> longevity. In a total of 15 trials (13 on OP50, 2 on HT115) bacteria we observed a slight decrease in <i>skn-1b</i> longevity compared to WT in 4 trials (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009358#pgen.1009358.s004" target="_blank">S4</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009358#pgen.1009358.s005" target="_blank">S5</a> Tables). …”

Table_1_Cashew nut (Anacardium occidentale L.) and cashew nut oil reduce cardiovascular risk factors in adults on weight-loss treatment: a randomized controlled three-arm trial (Br... by Talitha Silva Meneguelli (18885979)