Image2_Deciphering the Active Compounds and Mechanisms of HSBDF for Treating ALI via Integrating Chemical Bioinformatics Analysis.TIF by Yanru Wang (187231)

“…<p>The Huashi Baidu Formula (HSBDF), a key Chinese medical drug, has a remarkable clinical efficacy in treating acute lung injury (ALI), and it has been officially approved by the National Medical Products Administration of China for drug clinical trials. …”

Image1_Deciphering the Active Compounds and Mechanisms of HSBDF for Treating ALI via Integrating Chemical Bioinformatics Analysis.TIF by Yanru Wang (187231)

“…<p>The Huashi Baidu Formula (HSBDF), a key Chinese medical drug, has a remarkable clinical efficacy in treating acute lung injury (ALI), and it has been officially approved by the National Medical Products Administration of China for drug clinical trials. …”

The deamidation of N15 does not depend on deamidation of N71. by Ignacio de la Mora-de la Mora (435666)

“…<p>Native gel electrophoresis of the WT (A) or the N71D mutant (B) after incubation at 1mg/mL in TE buffer at 37°C with 3.5 mM GAP in a temporal course of 5 hours. …”

The morphogenesis and development of VM dopaminergic neurons is disturbed in <i>Dkk1^{<b>−/−</b>}</i> embryos. by Diogo Ribeiro (230483)

“…<p>(A) <i>Dkk1^−/−</i> embryos at E17.5 revealed an absence of most facial and head structures. …”

Representative micrographs of the healing MCL after PBS or IL-1Ra treatment. by Connie S. Chamberlain (440242)

“…In contrast, proliferating cells decrease on day 5 (g–h) after IL-1Ra administration.…”

Expression profiles of osmotic signaling related genes. by Lin Zhang (8926)

“…<p>This figure was modified from transcriptional regulatory networks of abiotic stress signals and gene expression <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0097878#pone.0097878-Shinozaki1" target="_blank">[32]</a>. …”

The interplay of gravity and touch responses. by Ilya Loshchilov (3992330)

“…<p>The sensitivity to gravitropic (<i>w</i>_<i>g</i>) and thigmotropic (<i>w</i>_<i>t</i>) signals was set at (a) 0.5 and 0.5, (b) 0.1 and 0.9, and (c) 0.9 and 0.1, respectively. …”

DNA microarray analysis of clinostat-induced gene expression in <i>E. coli.</i> by Kotakonda Arunasri (385358)

“…The x-axis represents the fold change and the dark vertical lines represent cut-offs at 1.5 fold decrease and increase. The y-axis represents the p-values and the dark horizontal line indicates a p value cut-off of 0.05.…”

Identifying optimal cluster numbers in hierarchical cluster analysis. by Dolores Bernenko (16528426)

“…<p>(a) Reverse-ordered linkage values on a logarithmic scale. …”

First coronal temperature slice was compared against first coronal temperature slices at different sonication parameters. by Avinash Eranki (3842191)

“…Temperature curves obtained while sonicating at 0.5, 2, and 5 Hz PRF. The peak temperatures obtained were 50°C, 72°C, and 95°C for PRF of 0.5, 2, and 5 Hz, respectively.…”

Data_Sheet_1_Interplay Between Nanoplastics and the Immune System of the Mediterranean Sea Urchin Paracentrotus lividus.pdf by Carola Murano (10302947)

“…Upon transfer to PS NP-free CF, a significant decrease in fluorescence signal is observed, suggesting a fast cell clearance. …”

TRPV4 mediated calcium influx after stretch. by N. Pairet (5109128)

“…(B) Summary of the mean % Ca²⁺ response from the 60 sec after stretch, a 2.5 fold increase in the [Ca2+]_i was observed that was significantly decreased by 26% with the TRPV4 antagonist (1 <b>μ</b>M) GSK2193874 (184.5 ± 5.07 vs 248.6 ± 10.17). …”

Cytoprotective gene regulation is essential to lifespan extension by diverse mechanisms. by David E. Shore (123998)

“…Lifespan was measured in three replicates comprising an average of 103 worms per condition. Data is presented as mean lifespan (columns 1–4), change mean lifespan in comparison to an empty vector RNAi control (column 5), or as the change in the extension of lifespan induced by each long-lived mutant (columns 6–8; for clarity, only decreases >15% are shown). …”

Actin polymerization lead to YAP de-phosphorylation and nuclear localization. by Pradeep Reddy (371909)

“…<p>A. The levels of pYAP are decreased after treatment with jasplakinolide. …”

Determinants of Renal Tissue Oxygenation as Measured with BOLD-MRI in Chronic Kidney Disease and Hypertension in Humans by Menno Pruijm (541636)

“…The mean cortical and medullary R2* values ( = 1/T2*) were calculated before and after administration of IV furosemide, a low R2* indicating a high tissue oxygenation. …”

Autophagy is associated with viral antigen presentation. by Sarah R. Klein (336437)

“…Data are shown as percentage of positive cells (mean ± SD). The decrease in the percent of positive adenovirus-infected, siMHCII-transfected cells compared with adenovirus-infected, siNC-transfected cells was statistically significant. ** <i>P</i> < 0.01 (unpaired, two-tailed Student’s <i>t-test)</i>.…”

Changes in lacrimal tear and ocular surface parameters preoperatively, 1 day, 1 and 2 months postoperatively from preoperative value. by Yuli Park (772773)

“…(C) Change in corneal staining score from preoperative value. There was a statistically significant decrease in the corneal staining score at 1 and 2 months postoperatively but the dry eye group showed higher score than the no dry eye group (<i>P</i> <0.05). …”

Rer1 loss reduces γ-secretase activity, leading to abnormal Notch signaling and neural stem cell proliferation. by Taichi Hara (46246)

“…(M) Light microscopy of neurospheres (secondary) derived from the cerebral cortex of control and forebrain specific Rer1 cKO mice on E14.5. Scale bar, 250 μm. (N) Mean values of secondary neurospheres formed by 200 dissociated cells from control and forebrain-specific Rer1cKO mice in 8 independent wells in a 96-well plate. …”

Depressive- and anxiety-like behaviors were measured in WT and HIV-1 tg rats receiving daily oral dosing of meloxicam. by Christina L. Nemeth (561625)

“…<i>E,F</i>) In the open field test, meloxicam treated HIV-1 tg rats showed no differences in overall locomotion (<i>p</i>>0.05), but did show a significant decrease in distance traveled in the center of the open field, as compared to WT rats (*<i>p</i><0.05). …”

Biological interpretation of the chromatin models based on feature importance. by Remo Monti (4379632)

“…<p>For each macro-category (on the far left), each dataset considered is indicated (stage, structure and reference publication are specified), followed by three distinct plots showing (left to right): (1) a box plot overlaid to a violin plot showing the distribution of the coefficients assigned to each particular feature by LASSO; (2) the selection probability as estimated by <i>Bootstrap LASSO</i> (darker shades of green indicating higher probability); (3) the feature importance estimated as mean decrease in accuracy by RF (separately for the positive and the negative classes, indicated by red and light blue bars, respectively).…”