Image1_Identification of miRNAs related to osteoporosis by high-throughput sequencing.jpeg by Jiachun Huang (19350616)

“…The qRT-PCR results showed that miR-140-5p, miR-127-3p, miR-199b-5p, miR-181a-5p, miR-181d-5p, and miR-542-3p exhibited a decrease of 2.27-, 3.00-, 3.48-, 2.67-, 2.41-, and 1.98-fold (all P < 0.05) in osteoporosis compared to controls. …”

Synaptic potentiation reduces AP onset, threshold and AHPs. by Sung-Cherl Jung (261358)

“…Examples of APs traces recorded before (black) and 30 min (red) after conditioning stimulation are given for paired and unpaired conditions. Scale bars: 40 mV, 200 ms. (right panel) Pooled data. The threshold to fire the first AP was lowered initially after LTP induction and this decrease persisted throughout the recording episode. …”

Assessments of the Inhibitory Effects of YC-1 on hRMVECs. by Michael DeNiro (297385)

“…The effects of addition of VEGF, DMSO, SN50M, SN50, and YC-1 on EC lumen formation over the time course of 24 hours, with the bar graph highlighting EC lumens per high power field [HPF] at 24 hour time point. SN50 and YC-1 treatments significantly [***P<0.001] decreased the number of lumen formed in hRMVECs as compared to their respective controls, SN50M and DMSO, respectively. …”

Introduction of FOXA1 into AB32 cells alters progestin response. by Christine L. Clarke (169388)

“…Red - increased log fold expression, green - decreased log fold expression. (B) FOXA1 protein expression in AB32 cells and parent MCF-10A cells before and after viral transduction, compared with endogenous expression in T-47D cells. …”

HMGB1 induces Src activation. by Mengchen Zou (725646)

“…EA.hy926 cells were plated in the upper part of transwell chambers until the formation of a tight monolayer. The cells were preincubated with 1, 2.5, 5, 10 or 20μM PP2 (upper) or 0.5, 1, 2.5, 5 or 10 μM CGP77675 (lower) for 1 h, respectively. …”

Immune Profiles to Predict Response to Desensitization Therapy in Highly HLA-Sensitized Kidney Transplant Candidates by Julie M. Yabu (3174753)

“…Responders to desensitization therapy were defined as 5% or greater decrease in cumulative calculated panel reactive antibody (cPRA) levels, and non-responders had 0% decrease in cPRA. …”

Dopamine Neurons Change the Type of Excitability in Response to Stimuli by Ekaterina O. Morozova (3386927)

“…Furthermore, we analyzed how excitability type of the DA neuron model is influenced by changes in the intrinsic current composition. A subthreshold sodium current is necessary for a continuous frequency decrease during application of a negative current, and the low-frequency “balanced” state during simultaneous activation of NMDA and GABA receptors. …”

<i>Helicobacter hepaticus</i> Infection Promotes Hepatitis and Preneoplastic Foci in Farnesoid X Receptor (FXR) Deficient Mice by Alton G. Swennes (625045)

“…A significant decrease in Firmicutes, particularly members of the order Clostridiales, was observed in FXR KO mice (<i>P</i><0.05 and FDR<5%, ANOVA). …”

NGAL-R mediates apical-to-basolateral transcytosis of PC3, MT and Tf in confluent Caco-2 BBE cell monolayers. by Christian Langelueddecke (441233)

“…Means ± SEM of 9-14 experiments are shown. Data are fitted to a one-phase exponential decay function. …”

Contribution of <i>hlgABC</i> to USA300 virulence in mouse infection models and survival in human blood. by Natalia Malachowa (224375)

“…(C) Survival of wild-type and Δ<i>hlgABC</i> strains in heparinized human blood. There were 1.5×10⁷ LAC wild-type CFUs at 0 min and this number decreased to 2.4×10⁶ CFUs by 120 min. …”

Bifurcation diagram of one node of the model with respect to . by Emre Baspinar (19369102)

“…<p>Blue and red dots show the maximum and minimum values of during the course of simulation. We see that as we decrease to the values lower than 1.5, the system goes through a bifurcation (black dot) and switches to a regime with propagation waves. …”

Spatio-temporal changes in expression of pluripotency markers and self-organization of stem cell-derived aggregates in 3D culture. by Rachel E. DeJonge (3109986)

“…<p>(A-D) Expression of the pluripotency marker Nanog decreases as vesicles mature between differentiation days 5–8. …”

Flow cytometry of 24 hrs infected corneas shows reduced inflammatory cell percentages in <i>Lum</i>^−/− corneas. by Hanjuan Shao (276852)

“…<p>Total cells from control and infected corneas per genotype (n = 5) were subjected to FACS analysis. Cells were immunostained with F4/80 (macrophage or MΦ marker), Gr-1 (neutrophil or PMN marker) (A) and with APC-Annexin V for detecting apoptotic cells (B). …”

Cell viability for HaCaT cells exposed to cobalt chloride under low-calcium and high-calcium growth conditions. by Maria Klasson (10924075)

“…The cell viability was measured with Cell Titer Blue viability assay and a dose- and time dependent decrease in viability was seen for low-calcium (A) and high calcium (B) growth conditions.…”

Figure S3 from Inhibition of <i>MCL-1</i> and MEK Overcomes MEK Inhibitor Resistance in Triple-Negative and Inflammatory Breast Cancers by Mohd Mughees (15998547)

“…The SUM149-R cells showed a decrease in viability after treatment with the constant doses of AZD5991 (0.5, and 1µM) followed by the different doses of AZD6244.…”

Scatter-plots representing the relative expression levels of 21 miRNAs. by Patrícia M. Pereira (156295)

“…<p>The relative expression of the 21 miRNAs that were deregulated are represented for normal cervix (red), CINI-cervical intraepithelial lesion grade I (green), CINIII-cervical intraepithelial lesion grade III (blue) and squamous cervical carcinoma (black) samples. <b>A</b>) 8 miRNAs that showed relative decrease in expression in the transition from normal cervix through premalignant dysplasia to cancer. …”

Percent changes (Δ-values) in regulator levels of Separase proteolytic activity after IM treatment when compared to the corresponding untreated cells.¹ by Wiltrud Haaß (312818)

“…1<p>for representative corresponding immunostained Western blots see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042863#pone-0042863-g005" target="_blank">Figure 5</a> panels B and C.…”

Increased spleen weight in myrAkt1 overexpressing animals is due to increased erythropoiesis. by Rebekah K. O’Donnell (286522)

“…<p>An increased percentage of reticulocytes was found in the blood at 3–4 weeks (<b>A</b>) p<0.02. Staining against TER119 revealed an increase in red cell area in the spleens of endothelial myrAkt1 compared with control mice (<b>B</b>) (5x). …”

Anti-proliferative effects of neuregulin on MCF10AT cells by Bin Yao (4375)

“…</p> Quadruplicate cultures of MCF10AT cells were treated with and without 1 nM neuregulin 3 days after plating and cell counts were performed demonstrating a significant decrease in their growth 24 and 48 hours after treatment. …”

Data Fluency Digital Toolkit Poster - Minor Prize by Rachelle Orodio (1223955)