Direct Visualization of the Feedback Pulse by Leor S Weinberger (274196)

“…Performing the same exogenous Tat incubation with cells in which SirT1 is overexpressed from a retrovirus vector decreases the upward slope of the pulse (orange). …”

Myotonia-causing mutations and the putative binding pocket of the 9-AC inhibitor. by Kaituo Wang (6193994)

“…Therefore, the phenotype may reflect a decreased chloride affinity of an extracellularly accessible site. …”

Immunohistochemical analysis of transplanted tumors for examination of stromal reaction and angiogenesis. by Takeshi Takasago (12261918)

“…<p>(a and b) The area positive for αSMA, type1 collagen, fibronectin, and CD31 decreased in the anti-TNFα mAb group. …”

Effect of Oxidative Phosphorylation Inhibitors on <i>In Vivo</i> Tat Transport and Sensitivity of Fluorescence Detection on Plates. by Umesh K. Bageshwar (2271628)

“…Valinomycin (V; 50 μM) is a K⁺ ionophore, which collapses the Δψ. …”

VDR and the MEK/ERK signaling pathway are involved in cathelicidin induction by vitamin D analogs. by Mark Peric (261717)

“…Silencing of ERK1 and ERK2 was confirmed by qPCR (C; left panel). siRNA suppression of ERK1 and ERK2 resulted in reduced induction of cathelicidin mRNA by vitamin D analogs (C; right panel). Data are means±SD of a single experiment performed in triplicate and are representative of 2 to 3 independent experiments (*<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001; Student's <i>t</i> test).…”

Dephosphorylation of ERK1/2 is involved in the WIN-induced down regulation of MMP-9 mRNA, but not in the effect of WIN on MMP-9 protein. by Svantje Tauber (121637)

“…WIN treatment resulted in a dephosphorylation of ERK associated with inhibition of secretion, intracellular accumulation and decrease of MMP-9 mRNA (lanes 1 and 2). …”

NER damage recognition proteins DDB2 and XPC are longer-lived in HCEC than NHEK. by Justin D. Mallet (3111555)

“…However, the decrease is faster in NHEK for both CB and NS fractions when compared to HCEC, indicating a greater half-lives of DDB2 and XPC proteins in HCEC. …”

μCT analysis of organotypic cultured embryonic femurs in basal and 1,25(OH)2D3 conditions. by Emma L. Smith (716897)

“…C, μCT morphometric indices of the structure of the E11 embryonic chick femurs either non-cultured (NC) or organotypic cultured in basal and 1α,25(OH)₂D₃ media. Values are means ± s.d. (n = 4 femurs per group) *P < 0.05; **P < 0.01 increase or decrease in μCT bone morphometric indices of basal and 1α,25(OH)₂D₃ cultured femurs compared to non-cultured (NC) femurs. …”

Data Sheet 1_Global trends and future predictions of gastrointestinal ulcers in youth.pdf by Kun He (178646)

“…The projected decline highlights the potential effectiveness of current strategies and offers a positive outlook for future management.</p>…”

mass-spec-data-JCS-259145.zip by Lizbeth de la Cruz (11976157)

“…Human tsA-201 cells were transiently transfected with PI4KIIIα, EFR3B, and TTC7B (PI4KIIIα), PIP5KIγ, or Dishevelled 3 (Dvl3). …”

Properties of <i>Drosophila</i> circadian promoters. by Pål O. Westermark (3140802)

“…From top to bottom, left to right: p = 0.0023, p = 0.16, p = 0.29, p = 0.066, rank sum tests. The last p value (mean for CLK vs. no CLK) became much smaller when considering all expressed transcripts: p = 2.5×10⁻¹⁷, median ratio 1.4 CLK vs. no CLK (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006231#pgen.1006231.s008" target="_blank">S3 Table</a>). …”

Aspirin increases lipid hydrolysis. by Xiao-Bing Huang (4436575)

“…For box-and-whisker plots, the whiskers show the minima and the maxima within a 1.5 IQR. (G) The mRNA level of the expression of enzymes in fatty acid β-oxidation of wild-type worms treated with or without 100 μM aspirin. …”

Phenotype analysis, nephrin expression and evaluation of glomerular function in adriamycin exposed zebrafish. by Benedicte Eneman (4288033)

“…Representative images of the eye from 0, 10 and 30 μM adriamycin treated embryos 5 hours after injection are shown. RIGHT: A diagrammatic representation shows the quantification of the mean fluorescence intensity ± SD recorded in the retinal vascular bed. * P < 0.05 in comparison to condition without the addition of adriamycin.…”

The effect of HuR expression levels on Epi-induced ROS production in SW620 cells. by Guan-Liang Lin (2423170)

“…Cells were then treated with Epi (5 μg/ml) for 24 h. (A) The cellular H₂O₂ level was detected by DCF intensity and analyzed by Flow Cytometry. …”

ATP production vs. substrate limits with low cost respiration. by Philip Möller (646291)

“…<p><i>α</i>₁ = 1, <i>α</i>₂ = 1, <i>α</i>₃ = 10, Γ = 200, and <i>v</i>₁ is capped by a value within the range [0, +∞). …”

Threshold ecological response at Diablas lagoon. by Alistair W. R. Seddon (212860)

“…B) Phase plot to indicate the presence of alternative stable states (mangroves and microbial mat) in the lagoon system. The point at which the threshold between the two states was crossed is marked by a red dashed line. …”

Enhanced quality factor of polyvinyl formal (PVF) based nanocomposites filled with zinc oxide and carbon black nanoparticles for wireless sensing applications by Mohanapriya, M.K.

“…The incorporation of ZnO at 10% decreases Q-factor to 36.1. Incorporation of CBNP at 5% and ZnO at 5% further reduces the Q-factor to 13.7. …”
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Table1_Improved the Activity of Phosphite Dehydrogenase and its Application in Plant Biotechnology.XLSX by Tongtong Liu (2553457)

“…The PtxD_Q showed the highest catalytic efficiency (5.83-fold as compared to PtxD_R4506) contributed by the 41.1% decrease in the K_m and 2.5-fold increase in the k_cat values. …”

Interdependence of Non-Protein Thiols and Metronidazole Toxicity by David Leitsch (33135)

“…<div><p>(A) Metronidazole diminishes non-protein thiol levels in the cell. …”

DataSheet_1_Effects of Soluble and Insoluble Non-Starch Polysaccharides on Growth Performance, Digestive Enzyme Activity, Antioxidant Capacity, and Intestinal Flora of Juvenile Gen... by Yu Liu (6938)

“…Specifically, dietary supplementation with INSP significantly increased pepsin and intestinal lipase activity, while dietary supplementation with SNSP significantly decreased intestinal lipase activity and resulted in a significant decrease in plasma catalase, glutathione peroxidase, and total antioxidant capacity activity. …”