Image 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.tif by Fang Li (41162)

“…Further proteomics and metabolomics analyses revealed that CA significantly affected the tricarboxylic acid (TCA) cycle and protein metabolism, with 167 differentially expressed proteins and 350 altered metabolites identified after 180 min of treatment (FC > 2 or <0.5, p < 0.05, VIP > 1). Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. …”

Table 3_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.xlsx by Fang Li (41162)

“…Further proteomics and metabolomics analyses revealed that CA significantly affected the tricarboxylic acid (TCA) cycle and protein metabolism, with 167 differentially expressed proteins and 350 altered metabolites identified after 180 min of treatment (FC > 2 or <0.5, p < 0.05, VIP > 1). Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. …”

Table 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.xlsx by Fang Li (41162)

“…Further proteomics and metabolomics analyses revealed that CA significantly affected the tricarboxylic acid (TCA) cycle and protein metabolism, with 167 differentially expressed proteins and 350 altered metabolites identified after 180 min of treatment (FC > 2 or <0.5, p < 0.05, VIP > 1). Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. …”

NSL depletion leads to Pol II loss on target genes of the NSL complex. by Kin Chung Lam (157979)

“…<p>(A) The heatmap displays input-normalized Pol II binding signals for 5′ ends of <i>D. melanogaster</i> genes as captured by ChIP-seq of Rbp3 in S2 cells that had been treated with dsRNA against GFP. …”

Preoperative Localization and Robotic ROLL-Guided Biopsy of Internal Mamary Lymph Node by Fernando Ascanio Gosling (10031274)

“…The PET scan in September showed a decrease in the size of the lung nodules but an increase in the hypermetabolism of the lymph nodes on the left internal mammary artery (SUV max 5). …”

ImmTAC-mediated killing capacity is dependent on the levels of target antigen presentation. by Jane Harper (5855927)

“…NRQ = (RQ target gene/geometric mean RQ housekeeping genes) x 10⁴, RQ = Efficiency-CT. n = 3, 4, 5, 3 and 2 for Mel526, Mel624, MeWo, WM266-4 and A375, respectively. …”

DataSheet1_Economics of Crop Rotations With and Without Carinata for Sustainable Aviation Fuel Production in the SE United States.PDF by Omid Karami (11975405)

“…The least risky rotation is cotton-cotton-peanut, with a 58.9% probability of a positive NPV. Carinata can decrease the risk level of crop rotations by 8.1%, only if a contract price of $440.9/t is offered. …”

PTEN regulates β-catenin activity in mammary stem/progenitor cells. by Hasan Korkaya (159560)

“…<p>(A) Effects of the GSK3-β inhibitor (Bio) and the Akt inhibitor (perifosine) on activation of Akt/GSK3-β/β-catenin signaling as assessed by Western blotting using phospho-specific antibodies. …”

Grazing resistance and antiprotozoal activity in biofilm bacteria. by Carsten Matz (220196)

“…Bacteria were considered to be edible or toxic if predator numbers showed a significant increase or decrease relative to the non-food control treatment. …”

Table 3_High-throughput sequencing metabarcoding and network analysis elucidate the effects of soil fumigation and biostimulant on potato yield, rhizoctonia canker, and fungal comm... by Honoré Tekeu (16972074)

“…<p>This study investigated the impact of chloropicrin fumigation and a Bacillus species-based biostimulant applied alone or in combination in soil of potato crop over five key time-points in season. …”

Table 1_High-throughput sequencing metabarcoding and network analysis elucidate the effects of soil fumigation and biostimulant on potato yield, rhizoctonia canker, and fungal comm... by Honoré Tekeu (16972074)

“…<p>This study investigated the impact of chloropicrin fumigation and a Bacillus species-based biostimulant applied alone or in combination in soil of potato crop over five key time-points in season. …”

Table 2_High-throughput sequencing metabarcoding and network analysis elucidate the effects of soil fumigation and biostimulant on potato yield, rhizoctonia canker, and fungal comm... by Honoré Tekeu (16972074)

“…<p>This study investigated the impact of chloropicrin fumigation and a Bacillus species-based biostimulant applied alone or in combination in soil of potato crop over five key time-points in season. …”

Palladin induces SMC marker gene transcription through the myocardin-MRTF-SRF pathway. by Li Jin (40265)

“…Values represent the mean±SEM (n = 3). *, p<0.05; # p<0.01. B) SMA and SM22 promotor transcriptional activities were decreased in palladin null APSCs. …”

DAF-16 contributes to inhibition of <i>mec-4d</i>–dependent AVM degeneration associated with reduced IIS signaling. by Andrea Calixto (16070)

“…Scale bar, 5 µm. (F–G) <i>mec-4d</i> worms were treated from the time of hatching with the ROS scavenger trolox (100 µm) and ascorbic acid (AA, 50 mM); after 72 hours both somas (F) and axons (G) were protected several fold compared to control nematodes (mean value for each category is shown; error bars [<1%] not included; N = 3 of 30 worms each per group; *p<0.005 by Student's t test compared with control for the SoW and AxW category).…”

Blocked NF-κB activation inhibits cytokine-upregulated IgSF molecules expression, and MSC modulates cytokine-induced NF-κB nuclear translocation. by Li Wen (169316)

“…<p>A to C shows FCM analysis of HCE-T cells treated with BMS-345541 (5 µM), a NF-κB pathway inhibitor, significantly inhibited IFN-γ (100 U/ml) and TNF (100 U/ml) induced ICAM-1 (A), HLA-ABC (B), and HLA-DR (C) expression. …”

Applied anatomy of round window and adjacent structures of tympanum related to cochlear implantation by Shraddha Jain (12814967)

“…The dissected bones were photographed by a digital camera of 18 megapixels, which were then imported to a computer to determine various parameters using ScopyDoc 8.0.0.22 version software, after proper calibration and at 1× magnification. …”

Impact of Transcatheter Aortic Valve Implantation on Kidney Function by Rita Calça (7888694)

“…<div><p>Abstract Background: Chronic kidney disease (CKD) is frequently present in patients with aortic valve disease. Decreased kidney perfusion as a consequence of reduced cardiac output may contribute to renal dysfunction in this setting. …”

Impact of Transcatheter Aortic Valve Implantation on Kidney Function by Rita Calça (7888694)

“…<div><p>Abstract Background: Chronic kidney disease (CKD) is frequently present in patients with aortic valve disease. Decreased kidney perfusion as a consequence of reduced cardiac output may contribute to renal dysfunction in this setting. …”

Amino acid composition of cytosolic proteins hot spots and their flanks. by Natalia S. de Groot (366700)

“…A relative frequency of 0 for a given residue at a given position means that the residue occupies that position with a frequency identical to that in natural proteins. …”

Data Sheet 1_Chemopreventive and therapeutic effects of Hippophae rhamnoides L. fruit peels evaluated in preclinical models of breast carcinoma.docx by Dana Dvorska (19809111)

“…Microarray analysis (758 miRNAs) identified beneficial changes in nine oncogenic/tumor-suppressive miRNAs, including miR-10a-5p, miR-322-5p, miR-450a-5p, miR-142-5p, miR-148b-3p, miR-1839-3p, miR-18a-5p, miR-1949, and miR-347. …”