Image_3_GSTT1null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.jpeg by Shahid M. Baba (9766146)

“…This case–control study investigated the association of GST gene polymorphisms with the etiology and therapeutic outcome of B-ALL among Kashmiri population.</p>Methods<p>A total of 300 individuals including 150 newly diagnosed B-ALL patients and an equal number of age and gender matched controls were genotyped for five GST gene polymorphisms by polymerase chain reaction–restriction fragment length polymorphism technique (PCR-RFLP) and multiplex PCR techniques.…”

Table_1_Genomic, phenotypic and demographic characterization of Mycobacterium tuberculosis in Israel in 2021.xlsx by Yelena Losev (17198449)

“…The State of Israel has a very low level of TB endemicity and is at a pre-elimination phase. …”

Image1_Validation of potential RNA biomarkers for prostate cancer diagnosis and monitoring in plasma and urinary extracellular vesicles.PNG by Agnese Brokāne (14561396)

“…</p><p>Results: We found that the levels of NKX3-1 (p = 0.0008) in plasma EVs, and tRF-Phe-GAA-3b (p < 0.0001) tRF-Lys-CTT-5c (p < 0.0327), piR-28004 (p = 0.0081) and miR-375-3p (p < 0.0001) in urinary EVs significantly decreased after radical prostatectomy suggesting that the main tissue source of these RNAs is prostate and/or PCa. …”

Light microscopy localization of pSer9GSK3β in the mouse brain. by Emma Perez-Costas (367514)

“…<p><b>A)</b> Immunoblot of mouse brain lysates showing the specificity of the pSer9GSK3β antibody used and its comparison with an immunoblot for GSK3β. …”

LRRC15 expression is correlated with collagen and antiviral gene signatures. by Lipin Loo (462678)

“…<p><b>(A)</b><i>LRRC15</i>⁺ fibroblasts have an enhanced collagen gene signature. …”

Image_1_Genomic, phenotypic and demographic characterization of Mycobacterium tuberculosis in Israel in 2021.tif by Yelena Losev (17198449)

“…The State of Israel has a very low level of TB endemicity and is at a pre-elimination phase. …”

Impact of COVID-19 lockdown on smoking (waterpipe and cigarette) and participants' BMI across various sociodemographic groups in Arab countries in the Mediterranean Region by Al Sabbah, Haleama

“…RESULTS: Overall, the prevalence rate of smoking decreased significantly during the lockdown from 29.8% to 23.5% (p<0.05). …”
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DataSheet_3_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.docx by Siawosh K. Eskandari (12858206)

“…<p>Regulatory T cells (T_regs) have shown great promise as a means of cellular therapy in a multitude of allo- and auto-immune diseases—due in part to their immunosuppressive potency. …”

DataSheet_2_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.docx by Siawosh K. Eskandari (12858206)

“…<p>Regulatory T cells (T_regs) have shown great promise as a means of cellular therapy in a multitude of allo- and auto-immune diseases—due in part to their immunosuppressive potency. …”

DataSheet_1_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.xlsx by Siawosh K. Eskandari (12858206)

“…<p>Regulatory T cells (T_regs) have shown great promise as a means of cellular therapy in a multitude of allo- and auto-immune diseases—due in part to their immunosuppressive potency. …”

DataSheet_1_Histone lysine-specific demethylase 1 regulates the proliferation of hemocytes in the oyster Crassostrea gigas.docx by Xiaoyu Gu (576058)

“…</p>Methods<p>We conducted a comprehensive analysis by various means to verify the function of CgLSD1 in hematopoietic process, including quantitative real-time PCR (qRT-PCR) analysis, western blot analysis, immunofluorescence assay, RNA interference (RNAi) and flow cytometry.…”

Table_1_Farm-related determinants of food insecurity among livestock dependent households in two agrarian districts with varying rainfall patterns in Ghana.DOCX by Francis Sena Nuvey (6458915)

“…In an adjusted model, households raising cattle in the dry district [adjusted Odds Ratio (aOR) = 5.43, 95% CI: 1.94, 15.2] and being married (aOR = 9.48, 95% CI: 2.35, 38.3) were associated with moderate food insecurity. …”

Data Sheet 1_Pyrogenic carbon and carbonating minerals for carbon capture and storage (PyMiCCS) part II: organic and inorganic carbon dioxide removal in an Oxisol.zip by Maria-Elena Vorrath (21766673)

“…A 20-year forecast suggests net C-Sinks between 0.5 t and 28.7 t CO₂ ha⁻¹, driven by increased contributions from weathering, alongside a C-Sink loss of carbon due to biochar mineralization. …”

The USP7 DUB regulates FLCN protein levels. by Lene Clausen (9592329)

“…Briefly, either wild-type FLCN or the ΔE510 FLCN variant is fused to the C-terminus of a HA-tagged Ura3-reporter protein. In case of the ΔE510 FLCN variant, we expect the protein to be destabilized and degraded (Pac-Man), leading to reduced levels of the Ura3 protein and thereby a decreased growth in the absence of uracil. …”

Root Exudation of Phytochemicals in Arabidopsis Follows Specific Patterns That Are Developmentally Programmed and Correlate with Soil Microbial Functions by Jacqueline M. Chaparro (130585)

“…Cumulative secretion levels of sugars and sugar alcohols were higher in early time points and decreased through development. In contrast, the cumulative secretion levels of amino acids and phenolics increased over time. …”

Presentation_1_Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages.pptx by Charles Drummer (4533508)

“…</p>Results and Discussion<p>Our results showed that 1) HFD increases body wight, liver wight, plasma cholesterol levels, liver fat deposition, and NAFLD activity score (NAS score) in wild-type (WT) mice; 2) HFD increases the expression of caspase-11, GSDMD, interleukin-1β, and guanylate-binding proteins in WT mice; 3) Caspase-11 deficiency decreases fat liver deposition and NAS score; 4) Caspase-11 deficiency decreases bone marrow monocyte-derived macrophage (MDM) pyroptosis (inflammatory cell death) and inflammatory monocyte (IM) surface GSDMD expression; 5) Caspase-11 deficiency re-programs liver transcriptomes and reduces HFD-induced NAFLD; 6) Caspase-11 deficiency decreases extracellular acidification rates (glycolysis) and oxidative phosphorylation (OXPHOS) in inflammatory fatty acid palmitic acid-stimulated macrophages, indicating that caspase-11 significantly contributes to maintain dual fuel bioenergetics—glycolysis and OXPHOS for promoting pyroptosis in macrophages. …”

Image_1_Exposure to strong irradiance exacerbates photoinhibition and suppresses N resorption during leaf senescence in shade-grown seedlings of fullmoon maple (Acer japonicum).pdf by Mitsutoshi Kitao (785516)

“…As decreased F_v/F_m indicates photoinhibition, leaves in LH2 condition suffered the most severe photoinhibition. …”

Tuberculosis Therapy Modifies the Cytokine Profile, Maturation State, and Expression of Inhibitory Molecules on <i>Mycobacterium tuberculosis</i>-Specific CD4⁺ T-Cells by Kapil K. Saharia (3160167)

“…</p><p>Conclusion</p><p>TB treatment alters the functional profile of Mtb-specific CD4 T-cells reflecting shifts towards a less differentiated maturational profile and decreases PD-1 and CTLA-4 expression. …”

DataSheet1_Nanoscale Porphyrin Metal-Organic Frameworks Deliver siRNA for Alleviating Early Pulmonary Fibrosis in Acute Lung Injury.docx by Changmei Weng (7911851)

“…Zinc finger E-box binding homeobox 1 and 2 (ZEB1/2) are highly expressed in the early stage of ALI and are positively correlated with the progression of pulmonary fibrosis. Herein, we developed a nanoscale Zr(IV)-based porphyrin metal-organic (ZPM) framework to deliver small interfering ZEB1/2 (siZEB1/2) to alleviate early pulmonary fibrosis during ALI. …”

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway by Chakrabhavi Dhananjaya Mohan (773464)

“…<div><p>Overactivation of PI3K/Akt/mTOR is linked with carcinogenesis and serves a potential molecular therapeutic target in treatment of various cancers. …”