The effects of pravastatin on the normal human placenta: Lessons from <i>ex-vivo</i> models by Adelina Balan (3749380)

“…This data is reassuring and important for clinicians that consider the treatment of high-risk patients with pravastatin, a treatment that exposes some normal pregnancies to the drug.…”

Image1_Ablation Patterns of the Debris Covered Tongue of Halong Glacier Revealed by Short Term Unmanned Aerial Vehicle Surveys.jpeg by Wanqin Guo (450937)

“…The surface ablation rates show a clear negative exponential relationship with the measured debris thicknesses, well in accordance with previous studies. …”

Image1_HR-MS Based Untargeted Lipidomics Reveals Characteristic Lipid Signatures of Wilson’s Disease.TIF by Yixiao Zhi (11736269)

“…<p>Background and Aims: The diagnosis of Wilson’s disease (WD) is challenging by clinical or genetic criteria. A typical early pathological change of WD is the increased liver lipid deposition and lowered serum triglyceride (TG). …”

DataSheet2_Lateral impact response of circular hollow steel tubes with mid-span localized penetrating notches.docx by Xiaoli Huang (309237)

“…Compared with the energy absorption ratio (EAR) of the non-notch model, with increased impact energy, the EAR of the vertical notch model increased by 20.2%, 13.5%, and 17.3% on average. The horizontal and oblique notch models decreased by 28.2%, 61.0%, 42.4%, and 29.1%, 62.7%, and 49.3%, respectively. …”

DataSheet3_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.zip by Xiaowan Wang (9704207)

“…To investigate the effects of SQ, we established the experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum in vivo and doxorubicin hydrochloride (ADR)-injured apoptotic podocyte model in vitro. …”

DataSheet1_Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption.DOC by Qinglian Tang (9162473)

“…</p>Results<p>Gavage of Scu significantly decreased the DAI score, improved colon shortening, ameliorated the pathological score in DSS-treated mice with better efficacy than the positive drug, 5-aminosalicylic acid. …”

DataSheet4_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

“…To investigate the effects of SQ, we established the experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum in vivo and doxorubicin hydrochloride (ADR)-injured apoptotic podocyte model in vitro. …”

DNA Hypermethylation of <i>CREB3L1</i> and <i>Bcl-2</i> Associated with the Mitochondrial-Mediated Apoptosis via PI3K/Akt Pathway in Human BEAS-2B Cells Exposure to Silica Nanopart... by Yang Zou (102732)

“…In this study, the epigenetic regulation of low-dose exposure to SiNPs was evaluated in human bronchial epithelial BEAS-2B cells over 30 passages. Cell viability was decreased in a dose- and passage-dependent manner. …”

Image_2_Changes in Thoracic Cavity Volume After Bilateral Lung Transplantation.TIF by Woo Sik Yu (6551513)

“…</p>Methods<p>We reviewed 89 patients who underwent a pre-LTx pulmonary function test (PFT), chest computed tomography (CT) scan, and 1-year follow-up CT after LTx. …”

Table_9_Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis.xlsx by Jipeng Yan (8473710)

“…With a median follow-up of 19.0 months, further subgroup analysis also demonstrated some key gut microbial markers were related to disease severity, treatment response, and even prognosis of patients with AL amyloidosis.…”

DataSheet1_Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice.docx by Lu Xia (1509745)

“…Dimethyl fumarate (DMF) was used as the GSDMD N-terminal fragments (GSDMD-N) inhibitor and suspended in 0.5% sodium carboxymethyl cellulose (CMC) for orally administration. …”

DataSheet3_Lateral impact response of circular hollow steel tubes with mid-span localized penetrating notches.docx by Xiaoli Huang (309237)

“…Compared with the energy absorption ratio (EAR) of the non-notch model, with increased impact energy, the EAR of the vertical notch model increased by 20.2%, 13.5%, and 17.3% on average. The horizontal and oblique notch models decreased by 28.2%, 61.0%, 42.4%, and 29.1%, 62.7%, and 49.3%, respectively. …”

Table_7_Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis.xlsx by Jipeng Yan (8473710)

“…With a median follow-up of 19.0 months, further subgroup analysis also demonstrated some key gut microbial markers were related to disease severity, treatment response, and even prognosis of patients with AL amyloidosis.…”

Data_Sheet_1_iCa2+ Flux, ROS and IL-10 Determines Cytotoxic, and Suppressor T Cell Functions in Chronic Human Viral Infections.pdf by Subhasmita Mohanty (8542353)

“…Importantly treatment with an antioxidant led to increased IFN-γ and reduced IL-10 production in human chronic Hep-B/C samples suggesting overall a proximal regulatory role for iCa²⁺ influx, ROS, and IL-10 in determining the effector/ suppressive axis of CD8⁺ T cells.…”

Table_6_Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis.xlsx by Jipeng Yan (8473710)

“…With a median follow-up of 19.0 months, further subgroup analysis also demonstrated some key gut microbial markers were related to disease severity, treatment response, and even prognosis of patients with AL amyloidosis.…”

Enhanced cell death in Ku70 KD cells is caspase-dependent. by Mohamed K. Hassan (550762)

“…<p><b><i>A</i></b>. Ku70 KD and control PC-10 cells were treated with hyperthermia (42.5°C) for 6 h in presence or absence of caspase inhibitor (Z-VAD; 50 nM). …”

Image3_Ablation Patterns of the Debris Covered Tongue of Halong Glacier Revealed by Short Term Unmanned Aerial Vehicle Surveys.jpeg by Wanqin Guo (450937)

“…The surface ablation rates show a clear negative exponential relationship with the measured debris thicknesses, well in accordance with previous studies. …”

Supplementary file 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.pdf by Yulia Dwi Setia (21590591)

“…Parasite burden was assessed by histological analysis (H&E staining) and qPCR targeting 5S rRNA. Goblet cells were visualized using PAS-Alcian Blue staining and Muc2 immunohistochemistry. …”

Table_1_Metabolomics analysis of the effect of acidification on rhizosphere soil microecosystem of tea tree.xlsx by Jianghua Ye (13951983)

“…In this study, we analyzed the effects of acidification on the physicochemical properties, microorganisms and metabolites of tea rhizosphere soils with different pH values, and the results showed that with the increase of soil pH, the organic matter content, cation exchange capacity, microbial biomass carbon, microbial biomass nitrogen, microbial respiration intensity, bacterial number and actinomyces number in tea rhizosphere soil all showed an increasing trend, while the fungi number decreased. The results of soil metabolite analysis showed that 2376, 2377 and 2359 metabolites were detected in tea rhizosphere soil with pH values of 3.29, 4.74 and 5.32, respectively, and the number of similar compounds reached 2331, accounting for more than 98%. …”

Table_1_Mendelian randomization in blood metabolites identifies triglycerides and fatty acids saturation level as associated traits linked to pancreatitis risk.xlsx by Jiarui Mi (11170284)

“…The summary statistics of four pancreatitis datasets from FinnGen R5 and two pancreatitis datasets from UK Biobank were exploited as the outcome. …”