Anti-inflammatory and antinociceptive effects of the isatin derivative (Z)-2-(5-chloro-2-oxoindolin-3-ylidene)-N-phenyl-hydrazinecarbothioamide in mice by L.L.S.F.R. Dantas (10461438)

“…The number of abdominal writhings decreased with the increasing dose, but only 5.0 mg/kg COPHCT exhibited a significant response, with a reduction of 24.88%. …”

Promising Nanostructured Materials against Enveloped Virus by GABRIEL G. DE TOLEDO (10365557)

“…In the past years, coronaviruses have been a threat to humanity, causing severe epidemics of respiratory infections such as severe acute respiratory syndrome (SARS), in 2003, and Middle East respiratory syndrome (MERS) in 2012, and presently the SARS-CoV2 is causing the COVID-19 pandemic. …”

Heatmaps of the predicted [<i>POA</i>_<i>T</i>]_<i>i</i> at equilibrium for the five scenarios studied. by David Requena (498200)

Data_Sheet_1_miR-181b-5p May Regulate Muscle Growth in Tilapia by Targeting Myostatin b.docx by Zaoya Zhao (8071304)

“…</p><p>Conclusion: Taken together, our results suggested that miR-181b-5p could promote the growth of skeletal muscle by decreasing the MSTNb protein level in tilapia.…”

Effect of Pressure on the Vibrational Structure of Insensitive Energetic Material 5-Nitro-2,4-dihydro-1,2,4-triazole-3-one by Reiko I. Hiyoshi (2385688)

“…The Raman spectra of α form 5-nitro-2,4-dihydro-1,2,4-triazole-3-one (α-NTO, space group <i>P</i>1̄) were measured in a high-pressure vessel diamond anvil cell (DAC). …”

Table_5_Screening of Key Proteins Affecting Floral Initiation of Saffron Under Cold Stress Using iTRAQ-Based Proteomics.xls by Jing Chen (4762)

“…</p>Results<p>Protein expression profiles in flowering and non-flowering saffron buds were established using isobaric tags for relative or absolute quantitation (iTRAQ). A total of 5,624 proteins were identified, and 201 differentially abundant protein species (DAPs) were further obtained between the flowering and non-flowering groups. …”

Image_5_Screening of Key Proteins Affecting Floral Initiation of Saffron Under Cold Stress Using iTRAQ-Based Proteomics.JPEG by Jing Chen (4762)

“…</p>Results<p>Protein expression profiles in flowering and non-flowering saffron buds were established using isobaric tags for relative or absolute quantitation (iTRAQ). A total of 5,624 proteins were identified, and 201 differentially abundant protein species (DAPs) were further obtained between the flowering and non-flowering groups. …”

Table 5_Inoculation frequency and maize genotype influence plant growth-promoting effects of soil bacteria under low nitrogen conditions.xlsx by Lexie R. Foster (22235653)

Variations in the organization of nuclear content between normal (left), fibrocystic (middle) and metastatic (right) mammary epithelial cells (scale bar = 5 microns). by Vivek Nandakumar (189376)

“…Opacity of nuclear membrane (in blue) has been deliberately decreased to enable viewing of nuclear interior. Corresponding videos of these renderings are available in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0029230#pone.0029230.s008" target="_blank">Movies S3</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0029230#pone.0029230.s009" target="_blank">S4</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0029230#pone.0029230.s010" target="_blank">S5</a>.…”

DataSheet_5_Antibodies Against Pseudomonas aeruginosa Alkaline Protease Directly Enhance Disruption of Neutrophil Extracellular Traps Mediated by This Enzyme.pdf by Chendi Jing (5957117)

Table_5_Integration of transcriptome and metabolome analyses reveals sorghum roots responding to cadmium stress through regulation of the flavonoid biosynthesis pathway.xlsx by Zhiyin Jiao (14667626)

Image_5_Synergistic Antibacterial Activity of Designed Trp-Containing Antibacterial Peptides in Combination With Antibiotics Against Multidrug-Resistant Staphylococcus epidermidis.... by Dejing Shang (8037545)

“…In addition, the antibiotics in combination with the peptide significantly inhibited biofilm formation by MRSE 1208. A mechanistic study demonstrated that the Trp-containing peptides, especially I1WL5W and I4WL5W, which contain two tryptophan residues, disrupted bacterial inner and outer membranes, which promoted antibiotic delivery into the cytoplasm and access to cytoplasmic targets; however, L11W and L12W may have increased intracellular antibiotic concentrations by decreasing blaZ, tet(m) and msrA expression. …”

Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5 by Hansjörg Schwertz (197301)

“…Similar phenotypes were also observed in platelets isolated from a patient with Vici syndrome: an inherited condition caused by a naturally occurring, loss-of-function mutation in EPG5. …”

Data_Sheet_5_Exploring the potential mechanism of Xiaojin Pill therapy for benign prostatic hyperplasia through metabolomics and gut microbiota analysis.zip by Yuying Yang (4111534)

“…L-arginine plays a pivotal role in metabolic pathways encompassing pyrimidine metabolism, arginine biosynthesis, and the mammalian target of rapamycin (mTOR) signaling pathway. 16S rRNA sequencing revealed that XJP optimized the diversity and balance of intestinal flora in BPH rats by decreasing the Bacteroidetes/Firmicutes (B/F) ratio, enhancing the beneficial bacteria, such as Eggerthellaceae, Anaerovoracaceae, and Romboutsia, and suppressing the dysfunctional bacteria, such as Atopobiaceae, Prevotellaceae_NK3B31_group, Dorea, and Frisingicoccus. …”

Table_5_The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.xlsx by Yi Zhou (2723)

“…This study aims to elucidate the mechanism by which Lactobacillus plantarum G201683 (L. plantarum G83), a promising panda-derived probiotic, exerts a protective effect on intestinal inflammation in the dextran sulfate sodium- (DSS) induced panda microbiota-associated (DPMA) mouse model. …”

Table_3_Inhibition of Osteoblast Differentiation by JAK2V617F Megakaryocytes Derived From Male Mice With Primary Myelofibrosis.docx by Aikaterini Karagianni (13018905)

“…A mouse mRNA osteogenesis array showed increased expression of Noggin, Chordin, Alpha-2-HS-glycoprotein, Collagen type IV alpha 1 and Collagen type XIV alpha 1 (mostly known to inhibit bone differentiation), and decreased expression of alkaline phosphatase, Vascular cell adhesion molecule 1, Sclerostin, Distal-less homeobox 5 and Collagen type III alpha 1 (associated with osteogenesis) in JAK2^V617F megakaryocytes, compared to controls. …”

Table_1_Inhibition of Osteoblast Differentiation by JAK2V617F Megakaryocytes Derived From Male Mice With Primary Myelofibrosis.docx by Aikaterini Karagianni (13018905)

“…A mouse mRNA osteogenesis array showed increased expression of Noggin, Chordin, Alpha-2-HS-glycoprotein, Collagen type IV alpha 1 and Collagen type XIV alpha 1 (mostly known to inhibit bone differentiation), and decreased expression of alkaline phosphatase, Vascular cell adhesion molecule 1, Sclerostin, Distal-less homeobox 5 and Collagen type III alpha 1 (associated with osteogenesis) in JAK2^V617F megakaryocytes, compared to controls. …”

Table_2_Inhibition of Osteoblast Differentiation by JAK2V617F Megakaryocytes Derived From Male Mice With Primary Myelofibrosis.docx by Aikaterini Karagianni (13018905)

“…A mouse mRNA osteogenesis array showed increased expression of Noggin, Chordin, Alpha-2-HS-glycoprotein, Collagen type IV alpha 1 and Collagen type XIV alpha 1 (mostly known to inhibit bone differentiation), and decreased expression of alkaline phosphatase, Vascular cell adhesion molecule 1, Sclerostin, Distal-less homeobox 5 and Collagen type III alpha 1 (associated with osteogenesis) in JAK2^V617F megakaryocytes, compared to controls. …”

Body temperature dependent platelet count of functional platelets during torpor and arousal in natural hibernating Syrian hamster at 5°C ambient temperature. by Edwin L. de Vrij (550179)

“…C) Normal platelet count in summer-euthermic Syrian hamster (n = 5, open dots; n = 7, black dots). D) Platelet count decreases with lower body temperature from euthermic stage to deep torpor in the Syrian hamster (n = 31), both during natural hibernation as well as during forced hypothermia (n = 8, multiple sampling). …”

Exposure to trips and slips with increasing unpredictability while walking can improve balance recovery responses with minimum predictive gait alterations - Fig 5 by Yoshiro Okubo (589967)