SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during <i>Trypanosoma cruzi</i> Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Di... by Xianxiu Wan (101988)

“…SRT1720 treatment preserved the myocardial SIRT1 activity and PGC1α deacetylation (active-form) that were decreased by 53% and 9-fold respectively, in chagasic mice. …”

Misclassification risk and threshold noise. by Arne F. Meyer (546624)

“…(<b>B</b>) Receiver operating characteristic (ROC) analysis of classification performance for one estimated RF filter, obtained by varying the decision threshold applied to projection and subsequent plotting of resulting true positive and false positive classification rates, i.e. threshold varies along the curve. The (0, 1) point indicates optimal performance and corresponds to vanishing noise around the threshold. …”

TMT exposure differentially affects PER2 and c-Fos in the central amygdala (CE) based on time of exposure. by Harry Pantazopoulos (350654)

“…Photomicrographs depicting increased c-Fos expression at ZT 0 for a TMT0 animal (E) in comparison to a TMT12 animal (F). *significantly different from control group at that time point (p<0.05) **significantly different from control and experimental group at that timepoint (p<0.05). …”

Inhibition of GSK-3 influenced directional persistence and locomotion speed of human glioma cell migration. by Qifei Zou (492288)

“…(E) The relative step angle of representative four migrating cells in the presence or absence of LiCl. …”

Fig 2 - by Azam Shahvaroughi-Farahani (10924390)

Dynamics of Th1 cell population. by Beatriz Almolda (197655)

“…D) Histogramme showing the IFNγ protein levels detected by ELISA assay at the representative scores during the induction, peak and recovery phases of EAE (ANOVA and Tukey's post-hoc test). E<b>–</b>G) Photographs of double immunostained sections showing a representative CD4+Tbet+ cell found around blood vessels (BV) (arrows point to double-immunolabelled cell). …”

GSNO reduces fibrin branchpoint density, but does not alter the fiber density/branchpoint ratio. by Ryon M. Bateman (141170)

“…As GSNO concentration increased, branch junctions per area decreased, panel D. However, the ratio of fiber density to branch point density was insensitive to GSNO concentration, panel E. …”

Table 3_COVID-19 and the impact of physical activity on persistent symptoms.docx by Lauren E. Opielinski (21171152)

“…</p>Results<p>Physical activity (IPAQ-SF) declined in COVID-19 survivors from pre-COVID-19 infection to 8.5 ± 4.7 months after infection [3,656 vs. 2,656 metabolic equivalent of task (MET) min/week, 27% decrease, p < 0.001, n = 64] and rebounded to levels similar to pre-COVID-19 infection at 4.25 years after infection (p = 0.068, n = 43). …”

Table 2_COVID-19 and the impact of physical activity on persistent symptoms.docx by Lauren E. Opielinski (21171152)

“…</p>Results<p>Physical activity (IPAQ-SF) declined in COVID-19 survivors from pre-COVID-19 infection to 8.5 ± 4.7 months after infection [3,656 vs. 2,656 metabolic equivalent of task (MET) min/week, 27% decrease, p < 0.001, n = 64] and rebounded to levels similar to pre-COVID-19 infection at 4.25 years after infection (p = 0.068, n = 43). …”

Table 1_COVID-19 and the impact of physical activity on persistent symptoms.docx by Lauren E. Opielinski (21171152)

“…</p>Results<p>Physical activity (IPAQ-SF) declined in COVID-19 survivors from pre-COVID-19 infection to 8.5 ± 4.7 months after infection [3,656 vs. 2,656 metabolic equivalent of task (MET) min/week, 27% decrease, p < 0.001, n = 64] and rebounded to levels similar to pre-COVID-19 infection at 4.25 years after infection (p = 0.068, n = 43). …”

Datasheet1_Identification and analysis of differential miRNA–mRNA interactions in coronary heart disease: an experimental screening approach.docx by Jie Wang (16762)

“…In addition, the expression levels of complement C4 and C5 were found to be decreased, which provided a research basis for the prevention and treatment of this disease.…”

Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus. by Md Rezaul Islam (19649494)

“…<p><b>A)</b> Experimental scheme for the single nuclei RNA-seq experiment in Ts65Dn mice <b>B)</b> Unbiased clustering of hippocampal snRNA-seq data for 15884 nuclei represented on a UMAP. …”

Adoptive transfer of wild-type macrophages reduces lung fibrosis in myFoxm1^-/- mice. by Chinmayee Goda (8694597)

“…<p><b>(A)</b> Overexpression of <i>Dusp1</i> decreases expression of <i>Tnf</i>, <i>Il6</i> and <i>Il1b</i> in FOXM1-deficient macrophages. …”

Functional consequences of endogenous BST2 overexpression in high grade primary breast cancer cells. by Aejaz Sayeed (220486)

“…<b><i>Middle panel</i></b> - Data plots represent the fraction of BrdU positive proliferating cells in control (>100) and <i>BST2</i> knockdown cultures averaged from 5 optical fields scanned with a 20× objective. …”

Synthesis and Structure of (Ph₄P)₂MCl₆ (M = Ti, Zr, Hf, Th, U, Np, Pu) by Stefan G. Minasian (1904887)

“…While a reaction between MCl₄ (M = Zr, Hf, U) and 2 equiv of Ph₄PCl provided <b>3</b>, <b>4</b>, and <b>6</b>, syntheses for <b>1</b>, <b>2</b>, <b>5</b>, <b>7</b>, and <b>8</b> required multistep procedures. …”

Spiral-wave instability. by Soling Zimik (763123)

“…<p>Pseudocolor plots of the transmembrane potential <i>V</i>_<i>m</i> illustrating spiral-wave instabilities from our numerical simulations of the 2D ORd model for human ventricular tissue, with spatial gradients in (a) <i>G</i>_<i>Kr</i>, (b) <i>G</i>_<i>K</i>1, and (c) <i>G</i>_<i>NaCa</i> (because <i>G</i>_<i>NaCa</i> decreases with <i>g</i> (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230214#pone.0230214.g002" target="_blank">Fig 2</a>), the gradient in <i>G</i>_<i>NaCa</i> must be chosen to be the negative of that in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0230214#pone.0230214.e006" target="_blank">Eq (5)</a>); in (a)-(c) the local value of <i>ω</i> decreases from the top of the simulation domain to its bottom. …”

hyperfast.ckpt by David Bonet (17583906)

<i>Supporting data for “Microstructure and deformation mechanisms of ultrahigh-strength high-alloyed medium-carbon steel”</i> by Shuai Pan (9151349)

Splenic DCs remain quiescent following interaction with donor apoptotic cells in vivo. by Zhiliang Wang (373762)

“…<p>A) B6 mice were left untreated or injected i.v. with PKH67-labeled BALB/c apoptotic splenocytes. …”

Effect of concurrent training on gender-specific biochemical variables and adiposity in obese adolescents by Barbara de Moura Mello Antunes (6146822)

“…<div><p>Objective The purpose of the present study was to analyze the effects of a 20-week concurrent training (20 WCT) intervention program on gender-specific body composition and metabolic variables in obese adolescents.Subjects and methods Sample was composed of twenty-five obese adolescents, aged between 12 and 15 (13.4 ± 0.96) years. …”