An <i>in</i>-<i>silico</i> human cell model reveals the influence of spatial organization on RNA splicing - Fig 4 by Zhaleh Ghaemi (1507558)

“…C) This enhancement in mRNA production is highly sensitive to the localization of splicing particles in speckles; with only a 10% localization of splicing particles in speckles, the splicing reaction is enhanced ∼ 250-fold relative to the case with no speckles. D) Noise estimated as coefficient of variation (CV), decreases as a greater percentage of splicing particles are localized in speckles. …”

Heatmaps of GPCR expression and DE in solid tumors. by Krishna Sriram (5073854)

“…(C–D) The GPCRs that most frequently (i.e., in most tumor types) show increases (C) or decreases (D) in expression among the 45 tumor subtypes. …”

Comparison of methods for codon usage analysis. by Fran Supek (105927)

“…</i> Number of genomes (out of 461) where the column method outperforms the row method based on the area-under-ROC (AUC) statistic, and the rank correlation of the classifiers' per-gene class probabilities with experimental measurements of <i>E. coli</i> cytoplasmic protein abundances. All results were obtained in 4-fold crossvalidation. …”

Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrP^Sc Glycoform and Prion Infectivity by Elizaveta Katorcha (628696)

Alterations in nuclear-encoded OXPHOS sub-units in trophoblasts upon hypoxia. by Philippe Vangrieken (5683748)

“…<p>Protein levels of nuclear-encoded OXPHOS sub-units (Ndufb8, Sdhb, UQCRC2 and ATP5A respectively Complex I, II, III and V) (<b>A</b>) and mRNA transcript levels of nuclear-encoded OXPHOS sub-units (<i>Ndufb</i>, <i>Cycl-1</i>, <i>COXIV</i> and COXII respectively Complex I, III, IV and IV) (<b>B</b>) assessed in placental villous explants exposed to normoxia (control) or hypoxia for 3 h (n = 3) and protein levels of nuclear-encoded OXPHOS sub-units (Ndufb8, Sdhb, UQCRC2 and ATP5A respectively Complex I, II, III and V) (<b>C</b>) and mRNA transcript levels of nuclear-encoded OXPHOS sub-units (<i>Ndufb</i>, <i>Cycl-1</i>, <i>COXIV</i> and COXII respectively Complex I, III, IV and IV) (<b>D</b>) assessed in trophoblasts exposed to normoxia (control) or hypoxia for 24 h (n = 3-6/experimental condition (n = 3 experiments)). …”

Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins by Chunxiang Yao (834346)

MiR-150 expression promotes myeloid differentiation of CD34+ PBMCs from healthy donors. by Valerie A. Morris (462679)

“…MiR-150 transduced cells had significantly lower colony numbers compared to control transduced cells, with decreased erythroid colonies (BFU-E and CFU-E), decreased CFU-G and CFU-GM, but increased monocyte/macrophage colonies (CFU-M) (<i>P≤0.05</i> for comparisons, Student’s t-test). …”

Supplementary Material for: Clinical Utility of KidneyIntelX in Early Stages of Diabetic Kidney Disease in the CANVAS Trial by Lam D. (11931392)

“…<b><i>Results:</i></b> We included 1,325 CANVAS participants with concurrent DKD and available baseline plasma samples (mean eGFR 65 mL/min/1.73 m² and median UACR 56 mg/g). During a mean follow-up of 5.6 years, 131 participants (9.9%) experienced the composite kidney outcome. …”

Supplementary Material for: Phase angle as an indicator of depression in maintenance hemodialysis patients by Li X. (3218241)

“…There was a significant decrease in the prevalence of depression with increasing quartiles of PhA levels. …”

Quantification of group size effect for fish. by Jacques Gautrais (135854)

“…<p>(A) The five parameters , , , and are reported for each replicate, as a function of group size. …”

Simulating melodic and harmonic expectations for tonal cadences using probabilistic models by David R. W. Sears (4421653)

“…Using the Information Dynamics of Music model (or IDyOM) to simulate the formation of schematic expectations—a finite-context (or <i>n</i>-gram) model that predicts the next event in a musical stimulus by acquiring knowledge through unsupervised statistical learning of sequential structure—we predict the terminal melodic and harmonic events from 245 exemplars of the five most common cadence categories from the classical style. …”

Contraction of porous 70:30 col/PCL scaffolds containing seeded fibroblasts. by Paul P. Bonvallet (708039)

“…<p>Scaffold diameters were measured at each time interval to quantify contraction (plotted as percent decrease in scaffold diameter). Values represent means and standard deviation for five scaffolds per time point. …”

Loss of <i>Nf1</i> results in reduced bone mineral density (BMD), volume (BV), and trabecular architecture in <i>Col2.3Cre⁺;Nf1^flox/−</i> mice <i>in vivo</i>.... by Xiaohua Wu (120920)

“…<p>BMD was measured with pDEXA scans at 8 weeks (<b>A</b>) (*p<0.05) and 24 weeks (<b>B</b>) (*p<0.05, **p<0.01). …”

Table_11_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization anal... by Pei He (836326)

“…The multivariable logistic regression model showed that the decrease in CCR was associated with a higher risk of osteoporosis/fracture in all models (all P<0.05). …”

Dimolybdenum Paddlewheel Complexes with Cation Binding Sites as Electrolyte Additives to Manipulate the Solid-Electrolyte Interphase at Lithium Metal Anodes by Simon G. Gersib (21432741)

Image_3_Profiling the Urinary Microbiota in Male Patients With Bladder Cancer in China.TIF by Peng Wu (210686)

“…We observed increased bacterial richness (Observed Species, Chao 1 and Ace indexes; cancer vs. control; 120.0 vs. 56.0; 134.5 vs. 68.3; and 139.6 vs. 72.9, respectively), enrichment of some bacterial genera (e.g., Acinetobacter, Anaerococcus, and Sphingobacterium) and decrease of some bacterial genera (e.g., Serratia, Proteus, and Roseomonas) in cancer group when compared to non-cancer group. …”

Validation of <i>N</i>-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of <i>Trypanosoma cruzi</i> by Linda J. Herrera (2634154)

“…Moreover, metabolic labeling using myristic acid, azide showed a considerable decrease in the myristoylation of proteins in parasites treated with NMT inhibitors, providing evidence of the on-target activity of the inhibitors.…”

Inter-county mobility patterns reflect social distancing and travel restrictions. by Hengfang Deng (7003667)

“…The proportion of short-distance travel increases significantly to 37.5% after the social distancing rules. The fractions of mid and long-distance travel experienced about a 9.9% and 7.3% decrease, respectively. …”

Supplementary Material for: Polypharmacy and the Progression of Chronic Kidney Disease: Korean Cohort Study for Outcome in Patients with Chronic Kidney Disease by Min H.K. (10922121)

“…<b><i>Objective:</i></b> We aimed to analyze the renal hazard of polypharmacy in predialysis CKD patients with stage 1–5. <b><i>Method:</i></b> The data of 2,238 patients from a large-scale multicenter prospective Korean study (2011–2016), excluding 325 patients with various missing data, were reviewed. …”

Table_8_Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analy... by Pei He (836326)

“…The multivariable logistic regression model showed that the decrease in CCR was associated with a higher risk of osteoporosis/fracture in all models (all P<0.05). …”