A visual summary of the key study findings. by Joachim Worthington (8394213)

“…Modelling was used to estimate short- and long-term effects on colorectal cancer incidence and mortality, including ongoing impact of patient backlogs. A hypothetical mitigation strategy was simulated, with diagnostic and treatment capacities increased by 5% from 2022 to address backlogs. …”

A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

A shows the week of vehicle/dFBr injections dFBr in the IA2BC timeline followed by 1 week post-treatment washout period. by Steven Decker (13767223)

“…E. dFBr significantly decreases voluntary 20% ethanol consumption at the 4 hr time-point in female SD rats (n = 12/group). …”

Small Open Reading Frames, Non-Coding RNAs and Repetitive Elements in <i>Bradyrhizobium japonicum</i> USDA 110 by Julia Hahn (3279486)

“…We found that BjsR1 and BjsR3 have homologs outside the genus <i>Bradyrhizobium</i>, and BjsR5, BjsR6, BjsR7, and BjsR10 have up to four imperfect copies in <i>Bradyrhizobium</i> genomes. …”

Example IRT images from a meloxicam-treated (a) and placebo-treated control piglet (b) after castration. by Jessica L. Bates (667627)

Persistent HIV-1 suppression after deferiprone cessation in treatment-naive HIV-infected subjects. by Deepti Saxena (462177)

“…<p>Discontinuation trial design (DTD) is used to analyze long-term rebound following HIV-1 RNA—based segregation into a ‘Decrease’ and a ‘No decrease’ cohort, defined by viral load post-drug on Day 7 relative to viral load pre-drug on Day 1. …”

Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7) by Xiaodan Ding (838408)

“…Depletion of OGT in cells led to a decrease in the MLL5 protein level through ubiquitin/proteasome-dependent proteolytic degradation, whereas ectopic expression of OGT protein suppressed MLL5 ubiquitylation. …”

vRNP export-independent SG inhibition by influenza virus coincides with depletion of cytoplasmic poly(A) RNA and nuclear relocalization of PABP1. by Denys A. Khaperskyy (596268)

“…At 18 hpi, many PR8-infected cells have decreased cytoplasmic and increased nuclear poly(A) signal. …”

Table_1_Effects of Early Changes in Blood Pressure During Intravenous Thrombolysis on the Prognosis of Acute Ischemic Stroke Patients.docx by Zhong-Xiu Wang (9729359)

“…Patients with a lower baseline National Institute of Health Stroke Scale (NIHSS) score (8.25 ± 5.57 vs. 13.51 ± 7.42, P < 0.001), a higher Alberta Stroke Program Early CT Score (ASPECTS; 8.65 ± 1.82 vs. 8.13 ± 2.00, P = 0.005), decreased BP during thrombolysis (69.4% vs. 59.8%, P = 0.037), and steady BP (SD < 10 mmHg) were more likely to have a favorable outcome (73.9% vs. 60.6%, P = 0.019). …”

The influence of MTA1 expression on the malignant phenotypes of 1E8 cells. by Hongyan Wang (41596)

“…<p>(A) Treatment with MTA1 siRNA decreased MTA1 expression efficiently and enhanced E-cadherin expression. …”

Image5_Transferability of the PRS estimates for height and BMI obtained from the European ethnic groups to the Western Russian populations.JPEG by E. A. Albert (14430201)

Cluster-centroid profile analysis of the right V1 (cluster II) in healthy controls (blue) and patients with Leber's Hereditary Optic Neuropathy (LHON) (red). by Maria A. Rocca (356197)

“…In addition, compared to controls, the right V1 of LHON patients had an increased structural connectivity with the temporal occipital fusiform cortex and a decreased structural connectivity with the lateral occipital cortex and the occipital fusiform gyrus. …”

Table_5_A Specific IL6 Polymorphic Genotype Modulates the Risk of Trypanosoma cruzi Parasitemia While IL18, IL17A, and IL1B Variant Profiles and HIV Infection Protect Against Cardi... by Alexandra Gomes dos Santos (9449003)

Chronic hyperpolarization of dFB^23E10Ո^84C10 neurons promotes sleep and impairs sleep homeostasis. by Joseph D. Jones (13883524)

“…The raw data underlying parts A, B, C, D, E, G, H, I, and J can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003014#pbio.3003014.s033" target="_blank">S1 Data</a>. …”

Under-five mortality in the Rongo Sub-County of Migori County, Kenya: Experience of the Lwala Community Alliance 2007-2017 with evidence from a cross-sectional survey by Joseph R. Starnes (5729039)

“…</p><p>Conclusions</p><p>There was a significant decrease in under-five mortality before and after the presence of the Lwala Community Alliance. …”

Representative scatter plots of leukocyte populations during 1A8 neutrophil depletion. by Andrew S. Wagner (11331477)

“…Myeloid populations were assessed via staining using myeloid markers (α-Ly6C: HK1.4, APC, BioLegend) (α-Ly6G: 1A8, PerCP-Cy5.5, BioLegend) (α-CD11b: M1/70 clone, BV421, BioLegend) (α-F4/80: BM8, PE, BioLegend) (Fixable NIR Live-Dead: APC-Cy7, Invitrogen; cat #:L34975). …”

Supplementary Material for: Monoclonal Antibodies against the Human Somatostatin Receptor Subtypes 1–5: Development and Immunohistochemical Application in Neuroendocrine Tumors by Schmid H.A. (4126171)

“…Immunoreactivity of sstr1, sstr2a and sstr4 tended to decrease as tumor aggressiveness increased. sstr5 showed an opposite pattern, with higher staining in well-differentiated carcinomas compared with well-differentiated tumors. sstr5 immunoreactivity was correlated with the presence of metastases and angioinvasion, suggesting a possible association with more aggressive behavior. …”

Efflux potentiation by 4′,5′-<i>O</i>-dicaffeoylquinic acid in <i>S. aureus</i> (A), <i>E. faecalis</i> (B). by Yiannis C. Fiamegos (225675)

“…Cells were loaded with berberine at a concentration of 100 µg/ml, and then resuspended in buffer in the absence or presence of 4′,5′-<i>O</i>DCQA, at the same final concentrations used for the MIC determinations.…”

Detection of circ_0000006 and circ_0000160/hsa-let-7e-5p/UBQLN4 ceRNA network during the progression from AA to AD. by Yong Liu (6908)