Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of [¹⁸F]ENL30: A Potential PET Radiotracer for the 5‑HT₇ Receptor by Elina Tampio L’Estrade (6619937)

“…The 5-HT₇ receptor (5-HT₇R) is involved in a broad range of physiological conditions and disorders. …”

Flow diagram of the study. by Yoonjee Cho (15453454)

“…A total of 162 patients were included. The SOFA score on POD 5 was significantly higher in the High-decrease group compared with the Low-decrease group (5.2 ± 2.6 vs. 4.1 ± 2.3; mean difference: 1.1, 95% CI: 0.3 to 1.8; P = 0.005). …”

Baseline characteristics of patients. by Yoonjee Cho (15453454)

“…A total of 162 patients were included. The SOFA score on POD 5 was significantly higher in the High-decrease group compared with the Low-decrease group (5.2 ± 2.6 vs. 4.1 ± 2.3; mean difference: 1.1, 95% CI: 0.3 to 1.8; P = 0.005). …”

Ca²⁺ supplementation <i>in vitro</i> modulates cytokine production by primary human <i>i</i>NKT cells, Vδ2⁺ T cells, and MAIT cells. by Yusuf Cem Eskiocak (10789281)

Table 5_Effects of mind-body exercise in chronic cardiopulmonary dyspnoea patients—a network meta-analysis of randomized controlled trials.docx by Yilin Li (507257)

Neuroimaging findings. by Irene Flønes (849434)

“…C (upper lane): FDG-PET scan of the brain of patient 1 taken ~5 years later shows multiple foci of decreased glucose metabolism that correlate to the localization of the transient cortical signal changes on MRI. …”

<i>Prss21</i>^<i>-/-</i> mice display increased vascular permeability during luteal angiogenesis and decreased endothelial VE-cadherin expression. by Raymond J. Peroutka (8946971)

Paired t test for the (A) Slow-4 and (B) Slow-5 frequency band, <i>p</i> < 0.05, AlphaSim corrected. by Lei Gao (6566)

<b>Data and R Code for Reproducibility of </b><i>"Forest productivity decreases in response to recent changes in vegetation structure and climate in the latitudinal extremes of the... by Julián Tijerín-Triviño (20377161)

A) Calcium carbonate crystal size versus ferric ion concentration; B) SEM image at ferric ion concentration of 0.03 M; C) Ferric hydroxide colloid. by Jin Zhu (164147)

SAHA treatment decreases HDAC2 protein levels but does not affect the protein levels of other class I and IIa HDACs – 2^nd trial. by Michal Mielcarek (195209)

The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation by Ju-Hee Lee (135452)

“…In MCF7 human breast cancer cells, plumbagin significantly decreased the level of a human ortholog, 1, 4-phopshatidylinositol 5-kinase (PI5K)-1B, of yeast its3, and knockdown of PI5K-1B using siPI5K-1B increased the ROS level and decreased cell viability. …”

Table_5_Which Factors Affect the Occurrence of Off-Target Effects Caused by the Use of CRISPR/Cas: A Systematic Review in Plants.XLSX by Dominik Modrzejewski (5639621)

“…In addition, we ran a binary logistic regression analysis to verify five factors that may affect the occurrence of off-target effects: (1) Number of mismatches (2) Position of mismatches (3) GC-content of the targeting sequence (4) Altered nuclease variants (5) Delivery methods. …”

Image_5_Effects of dietary supplement with a Chinese herbal mixture on growth performance, antioxidant capacity, and gut microbiota in weaned pigs.PDF by Qinglei Xu (8497341)

“…A total of 400 weaned pigs [Duroc × (Landrace × Yorkshire)] were randomly allocated into one of four treatments: the CON group, fed with basic diet; the HM1 group, fed with basal diet supplemented with 0.5 g herbal mixture/kg diet; the HM2 group, fed with basal diet supplemented with 1.0 g herbal mixture/kg diet; or the HM3 group, fed with basal diet supplemented with 1.5 g herbal mixture/kg diet. …”

Impaired fibronectin and fibrinogen-cleaving activities of the E143A and H146A Zmp1 mutants. by Valeria Cafardi (490077)

“…(<b>C</b>) Decreased ability of E143A and H146A Zmp1 mutants to cleave fibronectin. 1 µM fibronectin from human plasma was incubated for 24 h at 37°C with no Zmp1 (control) or with 7.7 µM of wild type (WT), E143A or H146A Zmp1 in the presence of 0.5 mM ZnCl₂. 1 µg of fibronectin was analyzed by SDS-PAGE and Coomassie-blue staining. …”

FIGURE 5 from Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor by Shruti Lal (16805936)

“…<p>Phosphoproteomic screen identifies MCM2 Ser108 phosphorylation decreased by ZL-2201. <b>A,</b> Simple Western showing inhibition of pDNA-PK upon treatment with PRKDC siRNA, 300 nmol/L and 3.5 μmol/L of ZL-2201 ± 10 μmol/L bleomycin used in phospho-MS screen analysis. …”

<i>Trem1^−/−</i> mice develop smaller inflammatory lesions and show decreased cellular infiltrates at <i>L. major</i> infection sites. by Benjamin Weber (509906)

Decreased NK1.1^pos iNKT cell numbers in the peripheral organs of T cell-specific <i>Gfi1</i>-deficient mice. by Toshiaki Yasuoka (2827457)

Underlying data for Figs 6, S5, and S6. by Kun Wu (286745)

Flow chart. by Raphaele Houlbracq (20558509)

“…The difference in overall prevalence of OASI between 2010 (0.7%) and 2021 (1.0%) was not statistically significant after adjustment (aRR 1.24, 95% CI 0.91 to 1.68). By groups of classification, the prevalence of OASI increased significantly only in Group 2b [nulliparous term cephalic singleton with spatula delivery] from 2.6% (95% CI 1.2 to 5.6) in 2010 to 9.6% (95% CI 6.2 to 14.7) in 2021 (aRR 3.69, 95% CI 1.50 to 9.09), and did not differ statistically significantly in Group 2a [nulliparous term cephalic singleton with forceps delivery] from 3.2% (95% CI 1.8 to 5.7) in 2010 to 5.7% (95% CI 3.4 to 9.5) in 2021 (aRR 1.78, 95% CI 0.81 to 3.90).…”