Cardamonin inhibited tumor growth and decreased FASN and Raptor. by Peiguang Niu (17044532)

“…Cardamonin reduces the protein expression of Raptor, thereby inhibiting the mTORC1-regulated DNL pathway. This leads to a decrease in free fatty acid levels. Subsequently, the reduced levels of free fatty acids inhibit the activity of mitochondrial CPT-1 and induces mitochondrial dependent apoptosis. …”

HSV-1 infection modulates the fatty acid synthase. by Camilla Albano (16446679)

Recombinant Wnt5a reduces migration. by Martin Crozier (13804275)

Raw data for Fig 5 EdU and S phase assay. by Gokul Gopinathan (7930679)

Diagnostic performance of point-of-care and central laboratory cardiac troponin assays in an emergency department by Petra Wilke (4624219)

“…The ROC-derived optimal cut-off (OCO) levels for the different cTn assays clearly changed with decreasing kidney function. Impaired kidney function required OCO to be three to five times higher to achieve a comparable performance. …”

Preservation of the input genome (reservoir) and relationship of DNA meltdown to mutation rate (μ). by Zackery E. Plyler (18570572)

Predicted loss of function (pLOF) variants per exonic base pair versus non-synonymous to synonymous SNP ratio. by Zackery E. Plyler (18570572)

Schematic of the distorted flow generator and a 5-hole probe to measure the flow speed. by Elliott Donghyun Kim (19469973)

Kv7.2-Kv7.5 channel opener retigabine decreased spontaneous phasic contractions in guinea pig DSM isolated strips. by Serge A. Y. Afeli (431004)

Summary of miRNAs sequencing data quality. by Zhaowen Tan (12283502)

“…</p><p>Results</p><p>1) Hemodynamic tests revealed that the blood pressure of SHRs in the BFRT decreased significantly and that the blood pressure level of SHRs in the BFRT decreased more significantly than that of the simple resistance training groups did (P < 0.05). 2) Cardiac function tests revealed that the EF, FS, and MV E/A of SHRs in the BFRT significantly increased, whereas the HR, IVSd, IVSs, LVIDd, LIVDs, LVPWd, LVPWs and LV mass significantly decreased (P < 0.05). 3) Transcriptome sequencing revealed 9 differentially expressed miRNAs in the BFRT group compared with the SHR-SED group (2 miRNAs were significantly upregulated, and 7 miRNAs were significantly downregulated), with P < 0.05 and |log2FoldChange| ≥ 1 used as the criteria for differential significance. …”

The miRNA target genes. by Zhaowen Tan (12283502)

“…</p><p>Results</p><p>1) Hemodynamic tests revealed that the blood pressure of SHRs in the BFRT decreased significantly and that the blood pressure level of SHRs in the BFRT decreased more significantly than that of the simple resistance training groups did (P < 0.05). 2) Cardiac function tests revealed that the EF, FS, and MV E/A of SHRs in the BFRT significantly increased, whereas the HR, IVSd, IVSs, LVIDd, LIVDs, LVPWd, LVPWs and LV mass significantly decreased (P < 0.05). 3) Transcriptome sequencing revealed 9 differentially expressed miRNAs in the BFRT group compared with the SHR-SED group (2 miRNAs were significantly upregulated, and 7 miRNAs were significantly downregulated), with P < 0.05 and |log2FoldChange| ≥ 1 used as the criteria for differential significance. …”

A New Rotane Family:  Synthesis, Structure, Conformation, and Dynamics of [3.4]-, [4.4]-, [5.4]-, and [6.4]Rotane¹ by Lutz Fitjer (2466634)

“…This is the highest barrier of inversion ever reported for a cyclohexane. Promising candidates for even higher barriers are [6.5]rotane (<b>32</b>) and [6.6]rotane (<b>33</b>).…”

Supplementary Material for: Blood Outgrowth Endothelial Cells Reduce Hypoxia-Mediated Fibroblast to Myofibroblast Conversion by Decreasing Proangiogenic Cytokines by Nieves Torres E.C. (3643015)

Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers by Madisa V.G., Varaprasad

“…When the converter switch comes under active state two capacitors are discharged in series, similarly when the converter switch under inactive state those two capacitors are charged in parallel through the coupled inductor (CI) energy so, to get a high voltage at the converter output side. To reuse the leakage-inductor (LI) energy of the CI with the help of a passive clamp circuit for reducing the voltage stress across the switch, similarly switch has less resistance so conduction losses also decreased. …”
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Possible model of AVT system in mate-guarding, aggressive and courtship behaviors. by Saori Yokoi (430681)

“…(D) The homozygote <i>V1a2</i> mutant males exhibited decreased courtship displays and low aggression (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005009#pgen.1005009.g004" target="_blank">Figs. 4A and 4B</a>). …”

An Essential Role of the Arginine Vasotocin System in Mate-Guarding Behaviors in Triadic Relationships of Medaka Fish (<i>Oryzias latipes</i>) by Saori Yokoi (430681)

“…In contrast, heterozygote <i>V1a2</i> mutant males displayed decreased aggression, but normal mate-guarding and courtship behavior. …”

Effect of the AVT system on mate-guarding behavior. by Saori Yokoi (430681)

“…<p>(A) Manning compound injection decreased the guarding index. …”

Increased B-ADAM10 and decreased ADAM17 and TNF in Th2 biased strains. by Lauren Folgosa Cooley (733432)

Expression level of MiR-199a-5p, Claudin-5 mRNA, VEGF-A mRNA, in Serum, penumbra, and infarcted area between groups. by Guangxiao Ni (19713106)

Synonymous mutation frequencies and survival rates at imposed values of μ and λ are in conflict with traditional models of eukaryotic evolution and constraint. by Zackery E. Plyler (18570572)