Image_5_COVID-19 patients display changes in lymphocyte subsets with a higher frequency of dysfunctional CD8lo T cells associated with disease severity.tif by Luisina Ines Onofrio (17018217)

“…In addition, these patients showed a decreased frequency in IL-2-producing T conv cells. …”

Image_5_COVID-19 patients display changes in lymphocyte subsets with a higher frequency of dysfunctional CD8lo T cells associated with disease severity.tif by Luisina Ines Onofrio (17018217)

“…In addition, these patients showed a decreased frequency in IL-2-producing T conv cells. …”

Data_Sheet_1_Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos.PDF by Werner Giehl Glanzner (6859313)

“…The relative mRNA abundance of EIF1AX and EIF2A on D3 embryos, and the proportion of D4 embryos presenting a fluorescent signal for uridine incorporation were severely reduced in both KDM5B- and KDM5C-attenuated compared to control embryos, which indicate a delay in the initiation of the embryo transcriptional activity. …”

TAT.ARC protein administration in the contralateral ventricle decreased lesion volume in subregions of the ischemic territory after 24 h and 72 h after 60 min middle cerebral arter... by stefan donath (2809384)

Identification of yolk sac-born QH1⁺ cells in E5.5 chick embryos isolated from yolk sac chimeras. by Luc Pardanaud (201021)

“…<p>Transverse sections. A) Around the aorta (Ao) a population of QH1⁺ cells was present: the majority is LEP 100⁺ macrophages (arrowheads), but some QH1⁺/LEP100⁻CEC are present (dotted areas, arrow). …”

Analysis of gene expression during neurite outgrowth and regeneration-5 by Moriah L Szpara (67982)

“…</p><p>Published online 23 Nov 2007</p><p>PMCID:PMC2245955.</p><p></p>e points of DRG outgrowth (2, 5, 12, 24, and 40 hours) and 6 time points of SCG outgrowth (same as DRG plus 65 hour endpoint), for the 712 probe sets found to change more than 1.5 fold (p ≤ 0.05) in both datasets. …”

Proteasome-Mediated Proteolysis of SRSF5 Splicing Factor Intriguingly Co-occurs with SRSF5 mRNA Upregulation during Late Erythroid Differentiation by Osman Breig (388133)

“…In this study, we show that SRSF5 protein decreases drastically during erythroid cell differentiation, contrasting with a concomitant upregulation of SRSF5 mRNA level. …”

Table_5_Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus.xlsx by Gangqiang Guo (3278922)

“…Eleven methylation modifications (including elevated Am, 3′OMeA, m¹A, and m⁶A and decreased Ψ, m³C, m¹G, m⁵U, and t⁶A levels) were detected in CD4⁺ T cells of patients with SLE. …”

Video5_Magnetospheric responses to solar wind Pc5 density fluctuations: Results from 2D hybrid Vlasov simulation.MP4 by Hongyang Zhou (2352637)

“…With the new time-varying boundary setup, we introduce a monochromatic Pc5 range periodic density variation in the solar wind. …”

DAS and Y27632 down-regulated the mRNA and protein expression of CK8-RhoA/ROCK1 pathway and up-regulated TJs expression in intestines of infected mice. by Wen Wen Zheng (17721404)

Reducing SIRT1 activity increases, and increasing SIRT1 expression decreases, mitochondrial enzymes in C₂C₁₂ myotubes and rat skeletal muscle. by Kazuhiko Higashida (351645)

“…Values are means ± SE for 6–10 experiments per group. <i>p</i><0.5 versus control. (B) Suppression of SIRT1 activity by expression of dominant-negative SIRT1 H355A in rat triceps muscle by electroporation resulted in increases in mitochondrial proteins. …”

Peroxidase immunohistochemistry illustrating the changes in distribution pattern of SSTR1-5 in striatum of R6/2 and SSTR1/5^−/− mice. by Padmesh S. Rajput (206935)

“…<p>SSTR1(53 kDa) like immunoreactivity increased in striatum of R6/2 mice and abolished completely in SSTR1/5^−/− mice (<b>a</b>). SSTR2 (57 kDa) like immunoreactivity was increased in R6/2 and SSTR1/5^−/− mice (<b>b</b>). …”

The N-terminus of E1A specifically requires hBre1 for full activation of transcription. by Gregory J. Fonseca (421739)

“…Cells were then transfected with a constitutive β-galactosidase reporter, a Gal4 responsive luciferase reporter and a vector expressing the Gal4 DNA binding domain (DBD) alone, the Gal4 DBD fused to the N-terminus of E1A, or the Gal4 DBD fused to E1A CR3. Luciferase activity was measured. …”

Loss of FAM83A expression induces apoptosis and inhibits PI3K/Akt signaling. by Courtney A. Bartel (3993173)

“…(C) Live cells were stained with an antibody detecting the early apoptosis marker Annexin V. Knockdown of FAM83A resulted in elevated expression of Annexin V. …”

SRSF5 expression in primary ex-vivo erythroid precursors. by Osman Breig (388133)

“…After 2 days of maturation, these cells display a cell size decrease (low FSC), and cell surface phenotype changes, including Kit decrease and higher levels of CD71 and Ter119.B. …”

HMBOX1 reverses autophagy mediated 5-fluorouracil resistance through promoting HACE1-induced ubiquitination and degradation of ATG5 in colorectal cancer by Yan Gao (93649)

“…This results in decreased ATG5 levels, inhibiting autophagy and thus reducing 5-FU resistance in colorectal cancer cells both <i>in vitro</i> and <i>in vivo</i>. …”

Role of the −5 bp in <i>sodB</i> regulation. by Beth M. Carpenter (373215)

“…<p>WT G27, WT 26695, and the “−5 bp swap” strain were grown as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005369#s2" target="_blank">Materials and Methods</a>, and RNA was isolated under iron replete and iron-depletion shock conditions. …”

Flowchart of the steps involved in the high-throughput exoproteome screening assay (HESA). by Marion Schoof (11999106)

<i>In vitro</i> characterization of key marker proteins AQP5, ANO1, α-SMA, and CEACAM5 in cultures of the SG by immunofluorescence staining. by Patricia Klaka (4347595)

“…<p>(A) Stained secretory coil (sc) and duct (du) sections of native human sweat glands were analyzed in axillary skin tissue (a,d,g,j) compared to <i>in situ</i> glands (dashed lines) with outgrowing cells in 2D cultures (b,e,h,k) and 3D models (c,f,i,l). …”

Mitochondrial transport was reduced in A53T α-syn axons. by Li Li (14993)

“…<b>G</b>, Percentage of mobile mitochondria significantly decreased in A53T (~8%) compared to that in wt neurons (>30%). …”