Effect of rec.5S rRNA expression on the heteroplasmy level of KSS mutation. by Romuald Loutre (5410142)

“…<p>(<b>a</b>) Proportion of KSS mtDNA (Y axis) in cybrids cell lines with low expression of rec.5S rRNA versions (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0199258#pone.0199258.t001" target="_blank">Table 1</a>) after 8 weeks of cultivation in high glucose or glucose-free media, as indicated. …”

Inhibitors of 5-LOX block TRPM7-mediated cell rounding. by Hsiang-Chin Chen (247146)

“…<p>(A) Application of the 5-LOX inhibitors NDGA (10 µM), AA861 (10 µM), and MK886 (10 µM) to 293-TRPM7 expressing cells reduced cell rounding. …”

Susceptibility to COPD: Differential Proteomic Profiling after Acute Smoking by Lorenza Franciosi (600602)

“…SerpinB3 and Uteroglobin decreased after acute smoke exposure in young non-susceptible individuals exclusively, whereas Peroxiredoxin I, S100A9, S100A8, ALDH3A1 (Aldehyde dehydrogenase 3A1) decreased both in young susceptible and non-susceptible individuals, changes being significantly different between groups for Uteroglobin with iTRAQ and for Serpin B3 with iTRAQ and ELISA measures. …”

Inhibition of Cdk5 Activity Attenuates Dendritic Spine Formation and Maturation by Sebastian Jessberger (269496)

“…</p> <p>(B) Inhibition of cdk5 activity did not affect the formation but decreased the maturation of dendritic spines on apical dendrites of <i>DNcdk5</i>-expressing granule cells, whereas <i>DNcdk5</i>-expressing neurons with aberrantly targeted basal dendrites (BasalDNcdk5) showed a decrease in both formation and maturation of dendritic spines. …”

Related to Fig 3. by Mohammad Nafees Ansari (22232505)

“…(<b>Q</b>) Tumor growth kinetics recorded a significantly higher growth of BT-474_ZFX^OE (mean ± SEM, <i>n</i> = 5) than BT-474_VECT^OE tumors. …”

The relative frequency of AD patients as a function of the concentration of CSF-Aβ42 in subpopulations with low and high amyloid deposition density (amyloid load). by Dmitry V. Zaretsky (14034897)

Human glaucomatous trabecular cells produce SDF-1(5-67). by Alexandre Denoyer (160189)

“…MMP inhibitors batimastat (100 nM) and TIMP-1 (0.5 nM) induce a decrease in SDF-1(5-67) production, whereas TNF-α (50 ng/mL [2.9 nM]) and TGF-β2 (10 ng/mL [0.8 nM]) enhance the production of SDF-1(5-67). ** <i>P</i><0.01. …”

The diagram of RNF5 inhibition on KSHV lytic replication and PEL tumorigenesis. by Xiaojuan Li (351842)

“…In PEL cells with RNF5 silencing, loss, or inhibition (right), RNF5-mediated EphA3 and EphA4 ubiquitination and degradation are inhibited, and the levels of EphA3 and EphA4 are increased, probably facilitating dimerization and oligomerization, which decrease ERK and Akt activation and the expression of cell cycle CDK1 and hedgehog gene Smo, resulting in the inhibition of KSHV lytic replication and suppression of PEL growth.…”

EMT marker expression in primary tubular cell cultures grown in control (ctrl) and high glucose (HG) medium. by Barbara Torsello (4594873)

Schematic representation of key responses to MERS-CoV related to outcome. by Emmanuel Faure (391756)

“…Right panel: In the absence of recognition, the decrease in IRF 3 is associated to a decreased production of IL 12 and IFNγ. …”

Metascape pathway analysis on differentially expressed genes between progressive familial intrahepatic cholestasis (PFIC) and Alagille (ALGS) samples. by Alyssa Kriegermeier (4707226)

“…B) There was no decreased ATF6 gene expression in PFIC (n = 5) and ALGS (n = 5) livers compared to pNormal livers (n = 9) (p = 0.07 and p = 0.5 respectively).…”

Downstream molecular effects of knockdown of the expression of 5-HT_1B and 5-HT_1D receptors, on invasion and proliferation biomarkers in PaCa cells. by Nilgun Gurbuz (623605)

“…Knockdown of 5-HT_1B and 5-HT_1D receptors increase the epithelial marker, E-cadherin, and decrease its transcriptional repressor (TWIST).…”

Other bacterial species were not biotinylated by Agr-ID. Agr-ID and ATP, with or without biotin, were incubated with <i>Escherichia coli</i> (A), <i>Pseudomonas aeruginosa</i> (B),... by Lijuan Qian (3131523)

HEK293 cells were not biotinylated by Agr-ID. (A) Agr-ID and ATP, with or without biotin, were incubated with HEK293T cells for 30 min, followed by co-staining with Streptavidin-64... by Lijuan Qian (3131523)

Urinalysis (A-F) and blood chemistry test results related to kidney function (G and H). by Maria A. Colombatti Olivieri (21362615)

“…(B) Urinary pH. Only a significant decrease detected in cow 6878 at time pre-euthanasia (10 days). …”

Restoring large-scale brain networks in PTSD and related disorders: a proposal for neuroscientifically-informed treatment interventions by Ruth A. Lanius (3121746)

PD-1 deficiency does not significantly impact the pathogen load and pathology following <i>S</i>. <i>japonicum</i> infection. by Liaoxun Lu (179293)

Principal components analysis (a) and redundancy analysis (RDA) on 12 soil parameters as influenced by land-use management systems [Agri: Agriculture; Bioen: Bioenergy; CRP: Conser... by Emmanuel Amoakwah (13228938)

Syntaxin 5 Is Required for Copper Homeostasis in <em>Drosophila</em> and Mammals by Melanie Norgate (234832)

“…<div><p>Copper is essential for aerobic life, but many aspects of its cellular uptake and distribution remain to be fully elucidated. A genome-wide screen for copper homeostasis genes in <em>Drosophila melanogaster</em> identified the SNARE gene <em>Syntaxin 5</em> (<em>Syx5</em>) as playing an important role in copper regulation; flies heterozygous for a null mutation in <em>Syx5</em> display increased tolerance to high dietary copper. …”

The effect of low pH on the absorbance spectra of Rtms5^Y67F and Rtms5^Y67F/H146S. by Jion M. Battad (127989)

“…<p>Rtms5^Y67F (A) and Rtms5^Y67F/H146S (B) at a protein concentration of 0.25 mg/ml in 0.1 M potassium phosphate, pH 2.3 were incubated at 21°C and the absorption spectra determined at selected time points. …”