Specific cytolysis of ROR1⁺ tumor cells by CAR⁺ T cells. by Drew C. Deniger (747626)

“…<p>Four-hour chromium release assay was used to assess specific lysis by T cells at decreasing effector to target (E:T) ratios. (a) No DNA (CAR^neg), CD19RCD28⁺, CD19RCD137⁺, ROR1RCD28⁺, or ROR1RCD137⁺ T cells generated from healthy donor PBMC were challenged with EL4-ROR1⁺ cell line (closed squares), EL4 parental (ROR1^neg) cell line (open circles), Kasumi-2 cell line (closed inverted triangles), or NALM-6 cell line (open triangles). …”

Metformin reprograms TAMs and reduces inflammation in tumors. by Joao Incio (834672)

“…Data are presented as mean ± standard error in A, C and E. * p < 0.05, ** p < 0.01 vs. control.…”

HepR21 cells have increased resilience to nutrient deprivation compared to HepG2 cells. by Paramita Saha (473954)

“…A set of cells were kept as control. The survivability of HepR21 cells was found to remain unaffected while HepG2 cells were highly sensitive upon prolonged starvation with an overall 50% decrease in growth after 36 h of starvation. …”

DataSheet_1_Treatment With Lipopolysaccharide Induces Distinct Changes in Metabolite Profile and Body Weight in 129Sv and Bl6 Mouse Strains.docx by Maria Piirsalu (8627697)

“…According to the general linear model analysis (GLM), the 1.5 h LPS challenge in Bl6 caused a decrease of propionylcarnitine (C3), glucogenic amino acids, and acetylornithine (Ac-Orn), whereas the response of 129Sv included decreased concentrations of short-chain acylcarnitines (SCACs), citrulline, and elevation of glycerophospholipid (PCaa C42:0) and sphingolipid [SM(OH)C16:1]. 24 h after LPS administration, robust alterations in lipid profile were observed in both strains. …”

Effects of JNK3-N-Tat on the downstream effectors of JNK3 in PD models. by Jing Pan (95938)

“…<p>(A) Western blotting analysis of p-c-Jun, T-c-Jun and cytochrome c in SH-SY5Y cell extracts after treatment. …”

Serial changes in right ventricular ejection fraction and end-diastolic volume index during septic shock in humans by Olivier Court (55190)

Supplementary Material for: Trends in One-Year Recurrent Ischemic Stroke among the Elderly in the USA: 1994–2002 by Allen N.B. (4121671)

“…After adjustment for changing patient demographics and comorbidities, there was a 4.5% decrease in recurrent stroke rates from 1994–1996 (13.2%) to 2000–2002 (12.6%; p for trend <0.0001). …”

Image_1_Assessment of Epigenetic and Phenotypic Variation in Populus nigra Regenerated via Sequential Regeneration.tif by Weixi Zhang (1626823)

“…We detected a significant difference in methylation levels between first regeneration regenerated plants (G1) and those of the other four generations (G2–G5); there were no significant differences among the four later generations. …”

Data Sheet 1_Mechanical property changes of glial LC and RGC axons in response to high intraocular pressure.docx by Bochao Ma (14572143)

“…</p>Results<p>Compared to the control group, the Young's modulus of the glial LC decreased by 35.5%, 74.2%, and 80.6% at 4, 8, and 12 weeks of elevated IOP, respectively. …”

microRNA-14 as an efficient suppressor to switch off ecdysone production after ecdysis in insects by Kang He (189002)

“…<p>The precise increase and decrease of hormone ecdysone are critical for accurate development in insects. …”

Conditional ablation of <i>Tra2b</i> causes perinatal lethality and disturbed cortical patterning in mice. by Markus Storbeck (191895)

“…Cells of the ventricular and subventricular zones of the cortex show strongest decrease in staining intensity (black arrowhead). Scale bar equals 400 µm; ctx, cortex; th, thalamus; cpt, caudoputamen; cp, cortical plate; iz, intermediate zone; svz, subventricular zone; vz, ventricular zone; sn, septal nuclei; 3v, third ventricle; lv, lateral ventricle; pc, choroid plexus.…”

Antioxidant, genotoxic, antigenotoxic, and antineoplastic activities of apitoxin produced by Apis mellifera in Northeast, Brazil by Geysa Almeida Viana (7888517)

“…Apitoxin promoted a significant reduction in DNA damage index (idDNA) at all concentrations tested. …”

Right Ventricular Dyssynchrony Before and After Pulmonary Thromboendarterectomy in Patients with Chronic Thromboembolic Pulmonary Hypertension by Darrin J. Wong (4230487)

“…</p> <p><b>Conclusions:</b> There was a significant decrease in the standard deviation of the mean peak systolic strain and time to peak strain (dyssynchrony) of the three RV free-wall segments after PTE. …”

Assessment of SnO2 nanoparticles' impact on local Pichoclorum atomus growth performance, cell morphology and metabolites content by Bounnit, Touria

“…The current study investigates the ecotoxicity of SnO2 nanoparticles on a local marine algae isolate. Five different concentrations (1, 5, 25, 50 and 100mg/L) were tested and the culture was followed for 72h. …”
Get full text
Get full text

Table1_Sewage Sludge-Induced Effect on Growth, Enzyme Inhibition, and Genotoxicity can be Ameliorated Using Wheat Straw and Biochar in Pheretima posthuma Earthworms.docx by Hira Khalid (8844602)

“…Similarly, a maximum decrease in length was observed with sewage sludge (2.5%) followed by biochar (0.80%) at a 25% application rate. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”

Monobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells... by Somayeh Fani (2967933)

“…<p><b>(A, B) Quantitative study of gene expression, (C) western blot analysis of protein markers of the apoptosis pathway in MCF-7 treated cells with a concentration of 2.5 μg/mL (IC</b>_<b>50</b><b>) respectively</b>. …”

Human MADD fibroblast cells display similar mitochondrial defects as <i>xav</i> mutants. by Yuanquan Song (238595)

“…The expression of ROS related genes are also altered in Patient 1, with a ca. 20% decrease in <i>catalase</i> and 4.7 and 5.7 fold increase in <i>glutathione reductase</i> and <i>HSPA9</i> expression (N = 3–7 replicates of cells from passage 7–12; Student's t test, * p<0.05, ** p<0.01, *** p<0.001).…”

Supplementary Material for: Effect of SOM230 (Pasireotide) on Corticotropic Cells: Action in Dogs with Cushing’s Disease by Castillo V. (4126174)

“…SOM230 (pasireotide) is a multiligand somatostatin (SRIF) analog able to bind to somatostatin receptor (SSTR) subtypes 1, 2, 3 and 5, and trigger antisecretory and antiproliferative signaling cascades. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”