Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of [¹⁸F]ENL30: A Potential PET Radiotracer for the 5‑HT₇ Receptor by Elina Tampio L’Estrade (6619937)

“…The 5-HT₇ receptor (5-HT₇R) is involved in a broad range of physiological conditions and disorders. …”

Flow diagram of the study. by Yoonjee Cho (15453454)

“…A total of 162 patients were included. The SOFA score on POD 5 was significantly higher in the High-decrease group compared with the Low-decrease group (5.2 ± 2.6 vs. 4.1 ± 2.3; mean difference: 1.1, 95% CI: 0.3 to 1.8; P = 0.005). …”

Baseline characteristics of patients. by Yoonjee Cho (15453454)

“…A total of 162 patients were included. The SOFA score on POD 5 was significantly higher in the High-decrease group compared with the Low-decrease group (5.2 ± 2.6 vs. 4.1 ± 2.3; mean difference: 1.1, 95% CI: 0.3 to 1.8; P = 0.005). …”

Ca²⁺ supplementation <i>in vitro</i> modulates cytokine production by primary human <i>i</i>NKT cells, Vδ2⁺ T cells, and MAIT cells. by Yusuf Cem Eskiocak (10789281)

Tgfβ and p53 response in the SDS pancreas. by Marina E. Tourlakis (751986)

Table 5_Effects of mind-body exercise in chronic cardiopulmonary dyspnoea patients—a network meta-analysis of randomized controlled trials.docx by Yilin Li (507257)

Neuroimaging findings. by Irene Flønes (849434)

“…C (upper lane): FDG-PET scan of the brain of patient 1 taken ~5 years later shows multiple foci of decreased glucose metabolism that correlate to the localization of the transient cortical signal changes on MRI. …”

Paired t test for the (A) Slow-4 and (B) Slow-5 frequency band, <i>p</i> < 0.05, AlphaSim corrected. by Lei Gao (6566)

<b>Data and R Code for Reproducibility of </b><i>"Forest productivity decreases in response to recent changes in vegetation structure and climate in the latitudinal extremes of the... by Julián Tijerín-Triviño (20377161)

A) Calcium carbonate crystal size versus ferric ion concentration; B) SEM image at ferric ion concentration of 0.03 M; C) Ferric hydroxide colloid. by Jin Zhu (164147)

SAHA treatment decreases HDAC2 protein levels but does not affect the protein levels of other class I and IIa HDACs – 2^nd trial. by Michal Mielcarek (195209)

The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation by Ju-Hee Lee (135452)

“…In MCF7 human breast cancer cells, plumbagin significantly decreased the level of a human ortholog, 1, 4-phopshatidylinositol 5-kinase (PI5K)-1B, of yeast its3, and knockdown of PI5K-1B using siPI5K-1B increased the ROS level and decreased cell viability. …”

WSSV infection induces <i>Chi2</i> expression through E75. by Xin-Xin Wang (135520)

“…Results are presented as the mean ± SD from three replicates. (C) Inhibition of the WSSV-caused chitin decrease by <i>E75</i> knockdown, as analyzed by Raman spectroscopy (excitation at 532 nm). …”

Table_5_Which Factors Affect the Occurrence of Off-Target Effects Caused by the Use of CRISPR/Cas: A Systematic Review in Plants.XLSX by Dominik Modrzejewski (5639621)

“…In addition, we ran a binary logistic regression analysis to verify five factors that may affect the occurrence of off-target effects: (1) Number of mismatches (2) Position of mismatches (3) GC-content of the targeting sequence (4) Altered nuclease variants (5) Delivery methods. …”

Image_5_Effects of dietary supplement with a Chinese herbal mixture on growth performance, antioxidant capacity, and gut microbiota in weaned pigs.PDF by Qinglei Xu (8497341)

“…A total of 400 weaned pigs [Duroc × (Landrace × Yorkshire)] were randomly allocated into one of four treatments: the CON group, fed with basic diet; the HM1 group, fed with basal diet supplemented with 0.5 g herbal mixture/kg diet; the HM2 group, fed with basal diet supplemented with 1.0 g herbal mixture/kg diet; or the HM3 group, fed with basal diet supplemented with 1.5 g herbal mixture/kg diet. …”

Impaired fibronectin and fibrinogen-cleaving activities of the E143A and H146A Zmp1 mutants. by Valeria Cafardi (490077)

“…(<b>C</b>) Decreased ability of E143A and H146A Zmp1 mutants to cleave fibronectin. 1 µM fibronectin from human plasma was incubated for 24 h at 37°C with no Zmp1 (control) or with 7.7 µM of wild type (WT), E143A or H146A Zmp1 in the presence of 0.5 mM ZnCl₂. 1 µg of fibronectin was analyzed by SDS-PAGE and Coomassie-blue staining. …”

FIGURE 5 from Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor by Shruti Lal (16805936)

“…<p>Phosphoproteomic screen identifies MCM2 Ser108 phosphorylation decreased by ZL-2201. <b>A,</b> Simple Western showing inhibition of pDNA-PK upon treatment with PRKDC siRNA, 300 nmol/L and 3.5 μmol/L of ZL-2201 ± 10 μmol/L bleomycin used in phospho-MS screen analysis. …”

<i>Trem1^−/−</i> mice develop smaller inflammatory lesions and show decreased cellular infiltrates at <i>L. major</i> infection sites. by Benjamin Weber (509906)

Decreased NK1.1^pos iNKT cell numbers in the peripheral organs of T cell-specific <i>Gfi1</i>-deficient mice. by Toshiaki Yasuoka (2827457)

Underlying data for Figs 6, S5, and S6. by Kun Wu (286745)