Showing 17,121 - 17,140 results of 106,247 for search '(( 5 ((nn decrease) OR (a decrease)) ) OR ( e ((non decrease) OR (point decrease)) ))', query time: 1.70s Refine Results
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    Performance of the intact model. by Yaroslav I. Molkov (542831)

    Published 2015
    “…At lower values of <i>α</i> two distinct regimes exist: the first has a phase difference between flexor centers less than 0.5 (lower branch) which corresponds to the activation pattern shown in <b>A</b> (LF leads, RF activates on LF’s shutdown, then a pause until LF activates again) and the second regime has a phase difference greater than 0.5 (upper branch) when RF activates first and LF activates on RF’s shutdown (not shown on <b>A</b>). …”
  5. 17125

    Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

    Published 2019
    “…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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  6. 17126
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  9. 17129

    The Catalytic Subunit of the System L1 Amino Acid Transporter (<i>Slc7a5</i>) Facilitates Nutrient Signalling in Mouse Skeletal Muscle by Nadège Poncet (527942)

    Published 2014
    “…Thus, SLC7A5 modulates LNAA-dependent muscle mTOR-S6K signalling in mice, although it appears non-essential (or is sufficiently compensated by <i>e.g</i>. …”
  10. 17130

    Influence of chemical components of PVAC during storage of RBC. by Felix Sellberg (8098511)

    Published 2019
    “…In <b>(b)</b> values after 1 month (end of storage) are shown: PVA at 100 μg/mL increased hemolysis while PVAC at 2.5 mg/mL, 500 and, 100 μg/mL decreased the levels of hemolysis compared to the control.…”
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    Hepatic IRE1α/XBP1 pathway of the UPR is decreased in pediatric cholestatic liver disease (pCLD) samples compared to pediatric normal (pNormal) livers. by Alyssa Kriegermeier (4707226)

    Published 2022
    “…<p>A) Hepatic gene expression of IRE1α, XBP1s and downstream targets EDEM1 and ERdj4 were measured via qPCR. pCLD livers (n = 10) had decreases in IRE1α, XBP1, EDEM1 and ERdj4 expression compared to pNormal livers (n = 9). …”
  13. 17133

    Catalytic activity of PP2A following its demethylation by L-homocysteine and adenosine treatment. by Tejasvi Dudiki (827360)

    Published 2015
    “…Demethylation of sperm PP2A by L-homocysteine and adenosine results in decreased total phosphatase and PP2A catalytic activity. …”
  14. 17134

    Histamine 1 Receptor Blockade Enhances Eosinophil-Mediated Clearance of Adult Filarial Worms by Ellen Mueller Fox (774436)

    Published 2015
    “…Although fexofenadine-treated mice had decreased antigen-specific IgE levels as well as lower splenocyte IL-5 and IFNγ production, they exhibited a greater than fourfold rise in eosinophil numbers at the tissue site where adult <i>L</i>. …”
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  16. 17136

    Image_1_Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization.TIF by Emelia A. Assar (9201743)

    Published 2020
    “…We provide evidence suggesting the primary autophagy regulators Atg5 and FIP200 both play a role in cell motility and extracellular matrix adhesion. …”
  17. 17137

    Image_2_Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization.TIF by Emelia A. Assar (9201743)

    Published 2020
    “…We provide evidence suggesting the primary autophagy regulators Atg5 and FIP200 both play a role in cell motility and extracellular matrix adhesion. …”
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  19. 17139

    Programmed Release METTL3-14 Inhibitor Microneedle Protects Myocardial Function by Reducing Drp1 m6A Modification-Mediated Mitochondrial Fission by Boyue Huang (17051857)

    Published 2023
    “…RIP assay and mechanistic investigation confirmed that METTL3 inhibition reduced the translation efficiency of Drp1 mRNA by 5′UTR m6A modification, thus decreasing the Drp1 protein level and mitochondrial fragment after hypoxic-ischemic injury. …”
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