Synthesis, Anti-HIV Activity, and Metabolic Stability of New Alkenyldiarylmethane HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors by Bo-Liang Deng (2046553)

“…Their stabilities in rat plasma have also been investigated. Although introducing 5-chloro-2-methoxyphenyl or 3-fluoro-5-trifluoromethylphenyl groups into alkenyldiarylmethanes does not maintain the antiviral potency, the structural modification of alkenyldiarylmethanes with a 3-cyanophenyl substituent can be made without a large decrease in activity. …”

The MJ RON core complex is disrupted in the absence of RON5. by Josh R. Beck (242399)

“…RON2 levels are similarly reduced following knockdown of RON5. In contrast, only a minor decrease in RON4 and RON8 levels is observed. …”

Decreased macrophage and dendritic cell expression of IL-12 and TNFα in the lungs and spleens of IFNγ-KO mice infected with the epidemic strain <i>M. massiliense</i> CRM-0019. by Shaobin Shang (205922)

DAS and Y27632 down-regulated the mRNA and protein expression of CK8-RhoA/ROCK1 pathway and up-regulated TJs expression in intestines of infected mice. by Wen Wen Zheng (17721404)

Pathological pathways associated with SARS-CoV-2 infection in hamsters and COVID-19 patients were upregulated in hamsters challenged with SARS-CoV-2. by Malika Aid (7303874)

“…<p><b>(A-B</b>) Dot plots of differentially expressed genes increased in infected hamsters at 4 dpi that are upregulated (red) or downregulated (blue) in COVID-19 infected patients or the lung of hamsters infected with SARS-CoV-2. …”

μCT analysis of organotypic cultured embryonic femurs (E11) in basal and TGF-β3 conditions. by Emma L. Smith (716897)

“…<i>***P</i> < 0.01 increase in μCT bone morphometric indices of basal cultured femurs compared to non-cultured femurs ^#<i>P</i> < 0.05, ^###<i>P</i> < 0.001 increase/decrease in μCT bone morphometric indices of TGF-β3 (5 ng/mL and 15 ng/ml) cultured embryonic femurs compared to basal cultured embryonic femurs. …”

Image_5_Impairment of the Cell Wall Ligase, LytR-CpsA-Psr Protein (LcpC), in Methicillin Resistant Staphylococcus aureus Reduces Its Resistance to Antibiotics and Infection in a Mo... by Fan Li (49953)

Dispersion relation for the Hamiltonian hat{mathcal {H}}_0 of the π-flux cubic lattice model for different values of the parameter <em>a</em> (from top to bottom, <em>a</em> = 0, 0... by G Mazzucchi (557358)

“…</strong> Dispersion relation for the Hamiltonian \hat{\mathcal {H}}_0 of the π-flux cubic lattice model for different values of the parameter <em>a</em> (from top to bottom, <em>a</em> = 0, 0.5, 1).…”

Effect of fluoxetine treatment on the awake state, non-REM sleep, spindles, and REM sleep in adolescent and adult rats. by Judith R. Homberg (221999)

“…These states were measured at four time intervals: 17.30–18.30 p.m., 19.30–20.30 p.m., 5.30–6.30 a.m. and 7.30–8.30 a.m. Rats were housed under a reversed 12 hr day/light cycle, with lights on at 19.00 p.m. 14–17 Days following chronic fluoxetine treatment (12 mg/kg) wakefulness was increased and non-REM sleep was decreased in adult, but not adolescent rats during the 17.30–18.30 p.m. interval. …”

Impact of Advanced Hybrid Closed-Loop on Youth with High-Risk Type 1 Diabetes Using Multiple Daily Injections by Alisa Boucsein (14305409)

“…</p> <p>Research Design and Methods: This prospective 3-month single-arm, dual-center study enrolled 20 participants, and all completed the study. </p> <p>Results: HbA1c decreased from 10.5 ± 2.1% (91.2 ± 22.8 mmol/mol) at baseline to 7.6 ± 1.1% (59.7 ± 11.9 mmol/mol) and time spent in target range 70–180 mg/dL (3.9–10.0 mmol/L) increased from 27.6 ± 13.2% at baseline, to 66.5 ± 9.8% after 3 months of AHCL. …”

Dataset for: EGF Regulation of Proximal Tubule Cell Proliferation and VEGF-A Secretion by Diana Zepeda-Orozco (4396639)

17β-estradiol (E₂) combined with anti-AGE treatment pyridoxamine (Pyr) increases ER and decreases TGF mRNA in glomeruli of aged ovariectomized female mice. by Simone Pereira-Simon (325005)

Nearsightedness of Oxygen-Containing Functional Groups by Jonathan Miorelli (1708492)

Time-course studies for claudin-5 in mouse brain and CSF. by Ping-Sung Chiu (386303)

“…<p>Protein bands of (A) brain claudin-5 and (C) CSF claudin-5 from mice (n = 5) infected with <i>A. cantonensis</i>. β-actin and albumin were used as loading control. …”

The presence of consensus 5’SS motifs in various human loci. by Eliza S. Lee (715538)

“…<p>5’SS Motif depletion is based on the percent decrease between the observed number of motifs and the expected number based on tri-nucleotide frequencies (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0122743#pone.0122743.g006" target="_blank">Fig 6C</a>).…”

Western blot analysis of myocardial IRF5 protein expression. by Hao Xu (6530)

Deleterious role of IL-1β during infection with <i>B. thailandensis</i>. by Manoranjan Sahoo (189969)

The percentage of 12 experts participating in a modified Delphi survey that attributed the potential for impact (RS: reduced survival; DNI: decreased nutritional intake; D: displac... by Jennifer K. Fortin (755910)

Background comparison of relative abundance of 12 most abundant taxa. by John B. O’Connor (11529852)

Neutrophil elastase reduces host tolerance to infection with <i>B. thailandensis</i>. by Manoranjan Sahoo (189969)