Comprehensive analysis of non-synonymous missense SNPs of human galactose mutarotase (GALM) gene: an integrated computational approach by T. P. Krishna Murthy (12999761)

“…Structural analysis, PTM analysis and molecular dynamics simulations (MDS) were carried out to understand the effect of these mutations on the structural and physicochemical properties of the GALM protein. The residues R82G and E307G were found to be part of the binding site that resulted in decreased surface accessibility. …”

Knocking down and overexpression of EBI3 by siRNA and plasmid DNA have a constant effect during chondrogenesis of human MSCs. by Tong Zhang (103827)

The change in spatial predictability for 6 pathogens plotted over time for outbreaks introduced to districts with a range of population densities. by John R. Giles (11084573)

Loss of <i>Ramp2</i> leads to a proliferation defect in the labyrinth layer. by Mahita Kadmiel (4262311)

Evolution of R ratio (total consumer biomass change divided by NPP change) in regards to SST increase relative to reference period. by Vianney Guibourd de Luzinais (16871842)

“…<p>Where NPP is expected to decrease (a), or increase (b) under IPSL-SSP5-8.5 combination. …”

Melanoregulin levels influence melanosome characteristics in the choroid of <i>Hps5^ru2J</i> and <i>Oa1</i> mutant mice. by Rivka A. Rachel (137639)

“…<i>Mreg^dsu</i> mice show a significant increase in melanosome area, p<0.05, with melanoregulin over-expression (<i>Mreg^Tg</i>) and a decrease from wildtype in melanoregulin loss of function mice (<i>Mreg^dsu</i>), p<0.05, with no significant change in number of melanosomes in either case, p>0.05. …”

Cdk5 Deficiency Moderately Affects the Survival of Newborn Neurons by Sebastian Jessberger (269496)

“…<div><p>(A) The ratio of control and <i>DNcdk5</i>-expressing cells with correctly targeted dendrites (DNcdk5) was not changed 2, 4, and 8 wk postinjection. …”

Proteasome-mediated proteolysis of SRSF5 in late erythroid differentiation. by Osman Breig (388133)

“…Actin immunoblot was used as a loading control. Note that proteasome inhibition stabilizes SRSF5. …”

Establishment of cyprodinil resistance (CypR) as a novel selection marker for <i>B</i>. <i>cinerea</i>. by Thomas Leisen (9248883)

An in vitro anti-inflammatory effect of Thai propolis in human dental pulp cells by Nutthapong KANTRONG (16029384)

“…Results Stimulation of the pulp cells with IL-1β resulted in the activation of arachidonic acid metabolism via COX-2, but not 5-LOX. Incubation with various non-toxic concentrations of the propolis extract significantly inhibited upregulated COX-2 mRNA and protein expressions upon treatment with IL-1β (p<0.05), resulting in a significant decrease in elevated PGE2 levels (p<0.05). …”

CLAMP promotes nucleosome positioning at 5’ends genome-wide. by Jennifer Urban (313951)

Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation by Huang-Ju Tu (630766)

RNA Sequencing Reveals a Slow to Fast Muscle Fiber Type Transition after Olanzapine Infusion in Rats by Christopher J. Lynch (210400)

“…Male Sprague-Dawley rats were infused intravenously with vehicle or olanzapine for 24h using a dose leading to a mild hyperglycemia. RNA-Seq was performed on gastrocnemius muscle, followed by alignment of the data with the Rat Genome Assembly 5.0. …”

Figure S2: Depletion of RASSF1A alone or with RASSF1C results in disappearance of tight junctions and decrease of adherens junction, replaced by diffuse adherent junctions. from RA... by Fatéméh Dubois (5846192)

<i>T</i>. <i>brucei</i> total lysates impair a hepatic infection by <i>P</i>. <i>yoelii</i>. by Adriana Temporão (7841300)

Role of elastase in IL-1β and IL-18 processing and pyroptosis. by Manoranjan Sahoo (189969)

Comparison of parameter posterior distributions for the time-varying IFR model using <i>δ</i>_<i>p</i> as 7 days (Models 4, 5 and 6), 14 days (Models 7 and 8) and 21 days... by Siyu Chen (278663)

Mechanistic Insights on the Inhibition of C5 DNA Methyltransferases by Zebularine by Christine Champion (243238)

“…First, we observe an increase in the DNA binding when zebularine is incorporated into the DNA, compared to deoxycytidine and 5-fluorodeoxycytidine, together with a strong decrease in the dissociation rate. …”

Inflammation Regulates TMPRSS6 Expression via STAT5 by Delphine Meynard (87311)

“…The downregulation of Tmprss6 by inflammation in mice is not dependent on the Bmp-Smad pathway but occurs through a decrease in Stat5 phosphorylation. Moreover, Stat5 positively regulates Tmprss6 expression directly by binding to a Stat5 element located on the Tmprss6 promoter. …”

Main outputs of the earth system models considered in the current study. by Vianney Guibourd de Luzinais (16871842)