Demonstration that SP-1 and SP-3 negatively regulates the PP2A-Aα promoter. by He-Ge Chen (90952)

“…Expression of the exogenous pCMV-SP-1 in both types of ocular cells attenuated expression of the endogenous gene coding for PP2A-Aα. F. Expression of the exogenous SP-3 in both types of ocular cells induced only slight decrease in the luciferase reporter gene activity within 0 to 500 ng of the pCMV-SP-3 plasmid, which is not statistically significant. …”

Data_Sheet_1_The burdens of poverty during the COVID-19 pandemic.PDF by Julia Petersen (14168841)

“…To test for significant discrepancy, we opted for chi-square- and t-tests.</p>Results<p>The analysis sample compromised N = 8,100 individuals of which 4,2% could be classified as living at-risk-of-poverty. 23% of respondents living at-risk-of-poverty had a decrease in income since the beginning of the pandemic–twice as many as those not living at-risk-of-poverty, who reported more often an increase in income. …”

Metformin induced inhibition of HaCaT cells proliferation. by Fatima Ochoa-Gonzalez (2559499)

Table 5_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic... by Weifeng Zhen (12969341)

“…Ultra-protective ventilation (≤4 mL/kg predicted body weight) has the potential to further decrease ventilator-induced lung injury but may result in severe hypercapnia. …”

LFP changes in the CA1 area during learning sessions using 1:1 ratio schedule. by M. Teresa Jurado-Parras (2155477)

“…Note that peak spectral power values across the 3–8 Hz to the 30–100 Hz bands (<i>C-F</i>) tend to increase with each training session in WT mice, while spectral power values decreased or remained unchanged in GABA_B1a^-/- mice. …”

Cra expression noise increases the probability of fixation of a beneficial allele that is initially at a low frequency. by Michael Schmutzer (6656663)

“…<p>We simulated populations that started with a single cell carrying a beneficial allele (dissociation constant of 0.07 mmol g⁻¹) in a population of 2000 cells. …”

Arl2-K71R mutant causes mitochondrial fragmentation and has no effect on microtubule regrowth. by Dongliang Ma (19415424)

“…Differences were considered significant at **<i>p</i> < 0.01 and ****<i>p</i> < 0.0001, ns = nonsignificance. Scale bars; A = 20 μm; D = 5 μm; F = 100 μm. Source data can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002751#pbio.3002751.s015" target="_blank">S1 Data</a>. …”

DataSheet_5_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…The number of stings ranged from 7 to > 2,000, with a median of 52.5. Symptoms of envenoming were classified as mild, moderate, or severe in 80% (16), 15% (3), and 5% (1) of patients, respectively; patients with mild, moderate, or severe envenoming received 2, 6, and 10 vials of AAV as per the protocol. …”

DataSheet_5_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…The number of stings ranged from 7 to > 2,000, with a median of 52.5. Symptoms of envenoming were classified as mild, moderate, or severe in 80% (16), 15% (3), and 5% (1) of patients, respectively; patients with mild, moderate, or severe envenoming received 2, 6, and 10 vials of AAV as per the protocol. …”

IGF-1 induces an increase in <i>PRNP</i> expression through the PI3K-Akt-FOXO3a pathway. by Ting Liu (45625)

“…(C) and (D) Western blotting showing the relationship between the phosphorylation of FOXO3a and <i>PRNP</i> expression. Treatment with 50 and 100 ng/ml IGF-1 remarkably increased the phosphorylation of FOXO3a in both the SH-SY5Y and HeLa cell lines but caused little variation in the total level of FOXO3a. …”

Structural bioinformatics analysis of the crystallised CMT variants. by Aleksi Sutinen (10039145)

Arl2 KD affects mNPC proliferation in vitro. by Dongliang Ma (19415424)

“…(<b>B</b>) Bar graphs showing Arl2 expression levels at E12, 1.00 ± 0.00 A.U.; E13, 0.91 ± 0.10 A.U.; E14, 0.57 ± 0.17 A.U.; E16, 0.41 ± 0.16 A.U.; P1, 0.24 ± 0.09 A.U.; P7, 0.18 ± 0.06 A.U. …”

A3F translocations on ssDNA are distinct from A3G, but not due to intersegmental transfer. by Anjuman Ara (540372)

“…<p>(A–B) Summary of processivity factors for (A) A3F and (B) A3G on ssDNA substrates where the two deamination motifs were separated by 5- to 100- nt. …”

Overexpression results in additional interactions of excess HMR beyond the HMR core complex. by Andrea Lukacs (3752956)

Strain-Insensitive, Crosstalk-Suppressed, Ultrawide-Linearity Iontronic Tactile Skin from a Synergistic Segment-Embedded Strategy by Yanchao Zhao (5129174)

Strain-Insensitive, Crosstalk-Suppressed, Ultrawide-Linearity Iontronic Tactile Skin from a Synergistic Segment-Embedded Strategy by Yanchao Zhao (5129174)

DEX and proinflammatory molecules synergistically induced G-CSF. by Jesus Banuelos (4036886)

Antepartum fibrinogen concentration as a predictor of bleeding complications by Laura E. Dodge (7875416)

“…For every 100-mg/dL decrease in fibrinogen, the odds of a bleeding complication increased 1.63 times (95% confidence interval: 1.48–1.80). …”

Investigation of mechanisms underlying NMR-detected changes in the levels of choline metabolites and lactate following treatment of SF188 pediatric glioblastoma cells with PI-103 (... by Nada M. S. Al-Saffar (454143)

Engineering Two-Dimensional Mass-Transport Channels of the MoS₂ Nanocatalyst toward Improved Hydrogen Evolution Performance by Ge Wang (56838)

“…Because of the engineering of nanostructured channels, a reduction in overpotential by approximately 100 and 360 mV at −10 and −100 mA cm^–2, respectively, a decrease in the Tafel slope from 66.7 to 39.4 mV dec^–1, and a more stable operation can be achieved. …”