image2_Improved Survival and Retinal Function of Aging ZDF Rats in Long-Term, Uncontrolled Diabetes by BGP-15 Treatment.tif by Zita Wachal (10657409)

“…During the 12 months of treatment, 100% of BGP-treated animals survived compared to the non-treated ZDF group, where 60% of the animals died, which was a statistically significant difference. …”

Determination of mitochondrial temperature in intact human cells. by Dominique Chrétien (217681)

“…The MTY fluorescence reached at the end of phase I was significantly different (<i>n</i> = 10; ***) from the starting value of 50%, whilst the final value in phase IV was not. (D) (a) Linear increase of fluorescence of HEK293 cells (preloaded for a minimum of 10 min, with 100 nM MTY), according to cell number (using cell protein concentration as surrogate parameter); (b) Maximal rate of decrease of MTY fluorescence (percentage, blue circles, corresponding with mitochondrial warming) is not significantly affected by cell number, whereas initial fluorescence increase in the presence of cyanide (percentage, green circles, corresponding with initial rate of mitochondrial cooling) is modulated by cell number (values at the three cell concentrations tested were significantly different from each other). …”

Suppression of FcγRIa expression using shRNA prevents <i>E. coli</i> K1 entry into RAW 264.7 cells. by Rahul Mittal (202639)

“…E. coli</i> K1 or GBS that were bound or intracellular in control cells were taken as 100%. (E) Immunocytochemistry of <i>E. coli</i> K1 entered into FcγRIa⁻/− and CR3⁻/RAW cells after differential staining as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1001203#s4" target="_blank">Materials and Methods</a>. …”

Uniform downscaling of postsynaptic AMPA receptors across the dendritic tree in primary hippocampal cultures. by Mathieu Letellier (6803699)

“…(B) Representative EPSC trace evoked by a pair of brief depolarizations (+100 mV, 50-ms interval) of the presynaptic neuron. …”

Evaluation of Multidimensional Chromatography Coupled with Tandem Mass Spectrometry (LC/LC−MS/MS) for Large-Scale Protein Analysis:  The Yeast Proteome by Junmin Peng (156839)

“…We present a comparison of this experiment with a previously published yeast proteome analysis by Yates and colleagues (Washburn, M. …”

Log2 ratios from simulated exemplar tumors at varying purity levels. by Soroush Samadian (5028617)

“…The purity value for each tumor type (in gray), is the median purity value for each cancer type according to TCGA segments. As the purity decreases, we observed a corresponding decrease in log2ratios of tumor segments (reduction in color intensities). …”

Data_Sheet_1_Girls-Boys: An Investigation of Gender Differences in the Behavioral and Neural Mechanisms of Trust and Reciprocity in Adolescence.pdf by Imke L. J. Lemmers-Jansen (6328598)

“…</p>Methods<p>Here we investigate age-related gender differences in trust and reciprocity (n = 100, 51 female) and associated neural mechanisms (n = 44, 20 female) in adolescents between 13 and 19 years of age. …”

Data_Sheet_2_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Data_Sheet_2_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Image_1_Carbon monoxide promotes stomatal initiation by regulating the expression of two EPF genes in Arabidopsis cotyledons.jpeg by Xianjie Weng (14103780)

“…Consistent with this result, mutation of the CO biosynthesis gene HY1 resulted in a decrease of SI in hy1-100 plants, while overexpression of HY1 led to an increase of SI. …”

Image_2_Carbon monoxide promotes stomatal initiation by regulating the expression of two EPF genes in Arabidopsis cotyledons.jpeg by Xianjie Weng (14103780)

“…Consistent with this result, mutation of the CO biosynthesis gene HY1 resulted in a decrease of SI in hy1-100 plants, while overexpression of HY1 led to an increase of SI. …”

Structure Based <i>In Silico</i> Analysis of Quinolone Resistance in Clinical Isolates of <i>Salmonella</i> Typhi from India by Manoj Kumar (205700)

“…The present study assists in understanding the underlying molecular and structural mechanism for decreased fluoroquinolone susceptibility in clinical isolates as a consequence of mutations in DNA Gyrase.…”

Data_Sheet_1_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Whole Genome Sequencing to Investigate the Emergence of Clonal Complex 23 <em>Neisseria meningitidis</em> Serogroup Y Disease in the United States by Mary G. Krauland (157219)

“…This increase was accompanied by antigenic shift of three outer membrane proteins, with a decrease in the population that predominated in the early 1990s as a different population emerged later in that decade. …”

IL-1β, IL-6, and RANTES as Biomarkers of Chikungunya Severity by Lisa F. P. Ng (252501)

“…Statistical analysis showed that an increase in IL-1β, IL-6 and a decrease in RANTES were associated with disease severity.…”

Table_1_Carbon monoxide promotes stomatal initiation by regulating the expression of two EPF genes in Arabidopsis cotyledons.docx by Xianjie Weng (14103780)

“…Consistent with this result, mutation of the CO biosynthesis gene HY1 resulted in a decrease of SI in hy1-100 plants, while overexpression of HY1 led to an increase of SI. …”

Data_Sheet_1_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Characterization of G6PI-induced arthritis by Robert Bockermann (12583)

“…DBA/1 mice were immunized intradermally at the base of the tail with the indicated amounts of G6PI emulsified in complete Freund's adjuvant (CFA) to establish a dynamic immunization protocol allowing for an increase or decrease in disease severity. …”

Examples of nerve excitability measures showing significant relationship to serum potassium levels. by Delphine Boërio (571841)

“…<p><b>A</b>: Superexcitability, <b>B</b>: TEd20(90–100 ms) threshold decrease at end of 20% depolarizing current, <b>C,D</b>: TEh20(90–100 ms) and TEh40(90–100 ms) threshold decrease at end of 20% and 40% hyperpolarizing current (NB Negative threshold decrease indicates threshold were increased by hyperpolarization).…”

Supplementary Materials - Antitumor activity of new chemical compounds in triple negative mammary adenocarcinoma models by Maria V Giolito (8499600)

“…Results are shown as percentage of cell viability relative to the non-treated control (100%) and expressed as mean ± SEM. Experiments were performed in triplicate.…”