<i>Def6</i> morphants display defects associated with abnormal gastrulation movements. by Katerina Goudevenou (199855)

“…Two-tailed Student's <i>t</i>-tests showed a significant (p<0.001; three asterisks) decrease in length after injection of 2.5 ng <i>def6</i> MO versus wt embryos. …”

Simulations of synaptic excitation and inhibition. by Stefano Masoli (9928807)

“…(B) PSTH of responses elicited by a short train (5 impulses @100 Hz) to 20 MF, 20 AA, and 89 PF synapses. …”

Maternal Cypermethrin Exposure during the Perinatal Period Impairs Testicular Development in C57BL Male Offspring by Chaobin Huang (561304)

“…A histopathological analysis revealed a thinner seminiferous epithelium layer at PD21.5, interstitial hyperplasia at PD45.5, and germ cell vacuolization at PD90.5 in the 12 mg/kg/day CYP group. …”

Titan cells generation <i>in vitro</i> is impacted by various environmental conditions. by Benjamin Hommel (523072)

“…<p>(<b>A</b>) The sequence of media used at steps 2 and 3 of the protocol was crucial for titan cells generation: yeasts cultured in Yeast Peptone Dextrose (YPD) and transferred to minimal medium (MM) produced significantly more titan cells (cells >10μm, dotted grey line) than yeasts cultured in MM or YPD and transferred in MM or YPD, respectively; (<b>B</b>) Exposure to d light at step 3 had a positive impact on titan cells generation compared to incubation in the dark; (<b>C</b>) Raising the incubation temperature to 37°C at step 3 decreased titan cells formation compared to 30°C; (<b>D</b>) Modification of the initial pH of the MM used at step 3 impacted titan cells formation with pH 5.5 being optimal while a more acidic (pH = 4), a neutral (pH = 7) or an alkaline (pH = 8.5) pH inhibited titan cells formation; (<b>E</b>) The impact of hypoxia was tested by physical (closed cap) and by chemical (COCl₂ in MM at 1 nM) method and compared to normoxia (21% oxygen). …”

Trade-offs between hypocotyl and root growth in response to water stress. by Nils Kalbfuß (14248277)

“…Related to <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010541#pgen.1010541.g001" target="_blank">Fig 1</a></b> and <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010541#pgen.1010541.s005" target="_blank">S5 Fig</a></b>.…”

Gemcitabine and ATR inhibitor synergism and effects on the cell cycle and DNA damage in CH22 and U-CH17PII (Batch 2) by Chordoma Foundation (4391989)

“…</p><p><br></p><p dir="ltr">The following panels were treated according to panel A. The concentrations of gemcitabine and elimusertib used for CH22 were 5nM and 100nM, respectively, with those doses combined in the combination. …”

Hypothermia suppressed MNU-mediated DNA demage by TGF-β1 unregulation and TNF-α down-regulation. by Gangjun Du (450828)

“…<p>A and B. Hypothermia decreased MNU-induced BEAS-2B cell DNA demage examined by comet assay. …”

Comparison of the rescue ability of Gas7 wild-type and mutant protein. by Bo-Tsang Huang (162584)

“…The shGas7GFP specifically targets the sequence 5′-¹⁰⁸¹GTG GAA ATG ATC CGA CAA CAT¹¹⁰¹-3′ located on the open reading frame of <i>gas7</i> to knock down Gas7 expression. …”

LVS-immune CCR2 KO mice are similar to C57BL/6J mice in surviving maximal secondary lethal LVS challenge and generating immune T cells that control intramacrophage LVS growth. by Sherry L. Kurtz (9199442)

“…<p>A) Groups of five C57BL/6J or CCR2 KO mice were treated with PBS (naïve) or vaccinated by ID infection with 5 x 10⁰ CFU LVS. …”

Optimizing the aggregate core structure enhances Pept-in antimicrobial potency. by Guiqin Wu (760045)

“…<b>D-H:</b> P2 variants which are incompatible with the cross-beta core structure: L6G (P2); V7S (P2); P2 variants which are more compatible with the cross-beta core structure more compatible: V7Y (P2), P2_A5F. …”

Nbs1, Xrcc4, and Brca1 play distinct roles during individual repair events. by Nicole Bennardo (93380)

“…(F) Brca1-deficient cells show a decrease in S+DEJ. As in E, amplification products are shown from sorted GFP+ cells derived from I-SceI transfection of EJ5-GFP for WT and <i>Brca1−/−</i> cell lines.…”

Table 1_Effect of cholecalciferol on immune and vascular function in non-diabetic chronic kidney disease.docx by Kajal Kamboj (12769602)

“…</p>Results<p>In total, 62 subjects were studied. The mean age was 44 ± 12 years with 58% men. TH1 cells decreased from 17% (9%, 27%) to 11% (6%, 16%) (p=0.002) and TH2 cells increased from 9% (5%, 16%) to 16% (10%, 27%) (p=0.001) after cholecalciferol treatment. …”

TREK-1-deficient cells were protected from stretch-induced cell detachment. by Esra Roan (524613)

“…(D) Summary of 4 separate experiments indicating a significant decrease in cell detachment in TREK-1-deficient cells (5 images per well, 3 wells per cell type in each experiment). …”

The effect of gamete aging on no-choice fertilization crosses. by Nicole D. Fogarty (184459)

“…<p>Open bars denote fresh gametes (30 minutes after bundle breakup) and shaded bars denote aged gametes (4–5 hours). Double letters represent conspecific crosses (p = <i>A. palmata</i> and c = <i>A. cervicornis</i>) and these letters followed by an “e” or “s” represent eggs or sperm for each heterospecific cross. …”

DCLK1 regulates angiogenic factors. by Sripathi M. Sureban (455805)

Microelectrode simulation was performed to observe the recorded SPW-Rs in different regions of neural network. by Sadullah Canakci (4439137)

“…<p><b>(a)</b> SPW-R traces computed for a 65-electrode multi electrode array which spans a 3.5 × 3.5 mm² total area (-1750 μm to 1750 μm). …”

Superoxide flashes induce mitochondrial depolarizations, independently from the activity of the permeability transition pore. by Sandrine Pouvreau (240917)

“…Note the spatial and temporal colocalization of the increase in RPmt and decrease in TMRM fluorescence. <b>C</b> Total area of mitochondria presenting a flash or a depolarization per 1000 µm² cell per 100 s, in 5 cells under control conditions and after 20 min of treatment with 15 mM tiron (*: p<0.05 for control vs tiron, paired Wilcoxon Signed Rank test). …”

DataSheet_1_Exogenous BR delayed peach fruit softening by inhibiting pectin degradation enzyme genes.docx by Jianzhao Li (2709121)

“…All the above results showed that BR treatment had a positive effect on delaying the senescence of peach fruit and prolonging its storage period.…”

Fis binding site modifications, Langevin dynamics simulations of DNA breathing, and EMSA experiments, the first set. by Kristy Nowak-Lovato (101951)

“…FIS1 and FIS1S oligonucleotides were constant at 100 nM, and Fis protein ranged from 0 to 1.5 µM. (C) Langevin dynamics simulations demonstrating enhanced FIS2m2 local DNA breathing dynamics (compare to FIS2 in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002881#pcbi-1002881-g002" target="_blank">Figure 2</a>). …”

Local treatment of toxoplasmic retinochoroiditis with intravitreal clindamycin and dexamethasone by Yuslay Fernández Zamora (5763242)

“…Fourteen eyes (87.5%) improved ≥ 2 ETDRS lines of BCVA, of two or more Early Treatment Diabetic Retinopathy Study lines, BCVA remained stable in two eyes (12.5%), and no patient had decreased BCVA at the end of the follow-up period. …”