Effects of MTP knockdown on lipid droplet size and distribution. by Larry L. Swift (782762)

“…<p>(A) Lipid droplet size in white fat from control and knockdown mice was determined as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0181046#pone.0181046.g005" target="_blank">Fig 5</a>. …”

The weak activator Nrf1β/LCR-F1 is negatively regulated by its CTD. by Yiguo Zhang (512679)

“…The <i>left two panels</i> show western blotting of some of the above-transfected cell lysates with antibodies against either V5 (<b><i>a1</i></b>) or Xpress (<b><i>a2</i></b>). …”

DataSheet_1_In Vivo Characterization of Cortical and White Matter Microstructural Pathology in Growth Hormone-Secreting Pituitary Adenoma.pdf by Taoyang Yuan (8470440)

“…</p>Results<p>Compared to controls, we found 1) acromegaly had significantly increased cortical thickness throughout the bilateral cortex (pFDR < 0.05). 2) T1/T2-weighted ratio in the cortex were decreased in the bilateral occipital cortex and pre/postcentral central gyri but increased in the bilateral fusiform, insular, and superior temporal gyri in acromegaly (pFDR < 0.05). 3) T1/T2-weighted ratio were decreased in most bundles, and only a few areas showed increases in acromegaly (pFDR < 0.05). 4) Neurite density index (NDI) was significantly lower throughout the cortex and bundles in acromegaly (pTFCE < 0.05). 5) lower fractional anisotropy (FA) and higher mean diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD) in extensive bundles in acromegaly (pTFCE < 0.05). 6) microstructural pathology in the cortex and white matter were associated with neuropsychological dysfunction in acromegaly.…”

Plate 4 by Jenna Tomkinson (14757022)

“…</p> <p><br> There are 4 channels/stains:<br> - <strong>DAPI</strong> (DNA/Nuclei)<br> - <strong>GFP</strong> (ER)<br> - <strong>CY5</strong> (Mitochondria)<br> - <strong>RFP</strong> (Actin)<br> <br> There are NF1 Null and WT cells on this plate, with only the WT cells either not treated or treated with one of three siRNA constructs to decrease neurofibromin production using a dose curve.…”

Dendritic length of neurones was nearly constant in the rostromedial half of nucleus laminaris. by Jeremy Corfield (68936)

“…In D, median dendritic lengths for all cells located in a 10×10 µm square (n = 1 to 5) are plotted as a flat topographical map and colours represent dendritic lengths as shown in the legend. …”

Parameter sweep analysis of the Schlögl model. by Marco S. Nobile (541501)

“…<p>Results of a PSA-1D on the Schlögl model, in which the value of the stochastic constant is varied in the interval (the set of reactions and the values of all other parameters are given in Tables 4 and 5 in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091963#pone.0091963.s001" target="_blank">Text S1</a>). …”

Time course of <i>K</i>. <i>pneumoniae</i> susceptibility to CHX. by Stephen Buxser (11302550)

“…Details of linear regression parameters are given in S5 Table in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0256336#pone.0256336.s003" target="_blank">S2 Appendix</a>. …”

Mst1^−/− mice exhibit blunted MOG-specific proliferative and effector cytokine recall responses in vivo. by Konstantin V. Salojin (567844)

“…(<b>D</b>) Mice treated with an Mst1 inhibitor exhibit decreased severity of EAE. EAE was induced in C57Bl/6-Albino/129SvEv mice (n = 10 per treatment group) by immunization with MOGp35–55 in CFA and treated twice daily with the indicated doses of the Mst1 inhibitor LP-945706 administered by oral gavage in citrate buffed (pH 4.5, 0.1 M) 1% Tween 80 vehicle, starting one day after the onset of disease in 50% of the animals. …”

Gas–Liquid–Solid Migration Characteristics of Gas Hydrate Sediments in Depressurization Combined with Thermal Stimulation Dissociation by Chuanxiao Cheng (6898661)

“…Pressure compensation was first employed to study sediment recovery features. The expansion rate of a porous medium layer under combined dissociation and different backpressure (4.5, 3.5, 2.5, 1.5, and 0.1 MPa) was discussed. …”

Hit expansion around chloroxine. by Sam Barker (4832121)

“…This modification causes a significant decrease in this compound’s activity as a co-treatment with ceftazidime, with a <i>p</i>IC50 ≈ 3.4. 5,7-dichloro-2-methyl-8-quinolinol differs from chloroxine by addition of a methyl group in the 2-position (B). …”

Differential gene expression in bovine endometrial epithelial cells treated with IFNT2 or IFNTc1. by Kazuya Kusama (768185)

“…<p>(A) Venn diagram shows the number of gene with 1.5-fold changes among Control (Ctrl), IFNT2, and IFNTc1 treatment groups, and right table lists increased or decreased genes in IFNT2 vs. …”

Effect of PKC on high glucose induced TLR4 expression. by Jianping Peng (3478610)

“…<p>RPTC were treated for 24 hours with low glucose (5.5 mM), high glucose (30 mM), or the PKC inhibitor staurosporine (10 nM, added 1 hour before high glucose treatment), and the cell lysates were collected, TLR4 mRNA, phospho-PKC (pan), p-p38, p38 levels were examined via real-time PCR and Western blotting. …”

Concentration-response analysis of native <i>Eg</i>KU-1 on ASIC currents from DRG neurons. by Martín Fló (169408)

“…(B) Representative traces showing the acid (pH 6.1, 5 s) activated current under control conditions (left), after sustained (25 s) perfusion of α-DTX (center), and after 1 min washout (right). α-DTX (1 μM; n = 6) significantly decreased the current amplitude (44.5 ± 7.0%; P = 0.045). …”

Dependence of the dynamics on synaptic strength in the LIF inhibitory spiking model. by Omri Harish (778131)

“…From left to right: <i>J</i>₀ = 2 (blue), 1.5 (red) and 1 (black). A: Examples of single neuron membrane voltages (top) and net inputs, <i>h</i>, (bottom). …”

Effect of adipose-derived stem cells (ASCs) on cytokine levels in the bronchoalveolar lavage fluid. by Kyu-Sup Cho (770125)

“…ASC treatment significantly decreased IL-4, IL-5, and IL-13 but increased IL-10 and TGF—β in asthmatic mice. …”

HPV-16 E7 influences the balance between oxidized and reduced GSTP1. by Anna M. Mileo (258322)

“…In the first case, detection was performed after a 90 min or 5 h recovery period, while in the second case detection was performed after a 6 h period. …”

Ten daily doses of ethanol exposure reduced neurogenesis in hippocampal dentate gyrus during combined ethanol and LPS treatments by Liya Qin (46555)

“…(A) Ethanol (5 g/kg, i.g., 1 day) pre-treated group, LPS did not show a decrease in the number of PCNA and doublecortin-IR cells. …”

The MOA D2 surface recognition signal is trypsin sensitive. by Ellen Inga Bruske (3374342)

“…Trypsinisation resulted in a significant decrease of the antibody recognition signal (standard errors are given, p = 0.05 for ΔE5E2 (n = 4) and p = 0.003 (n = 3) for D2) in both cell lines. …”

Different conformational changes of sRNA Pab21 and Pab91 are associated with the sequential binding of the sRNP proteins. by Jean-Baptiste Fourmann (14570)

“…(<b>E</b>) Quantification of the decrease in the peak amplitude of the specific RNA positive signal at the λ_max wavelength, generated exclusively by addition of L7Ae to different aCBF5–aNOP10–sRNA complexes. …”

DataSheet6_Effect of crystal-photodetector interface extraction efficiency on Cerenkov photons’ detection time.docx by Carlotta Trigila (12472155)

“…In this context, the transit time spread in the crystal, highly dependent on the detector geometry, plays a crucial role in the photon detection time. In this work, we performed optical simulations in bismuth germanium oxide using 511 keV gamma with GATE to investigate the optical photons extraction when modifying the index of refraction at the crystal-photodetector interface and the crystal aspect ratio. …”