Supplementary Material for: Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes: FIDELIO-DKD subgroup from China by Zhang H. (2945919)

Supplementary Material for: Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes: FIDELIO-DKD subgroup from China by Zhang H. (2945919)

Supplementary Material for: Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes: FIDELIO-DKD subgroup from China by Zhang H. (2945919)

TO901317 (TO) inhibited the ROS production and JNK phosphorylation in Palmitate-treated HepG2 cells. by Ying Dong (41989)

“…Both TO (left panel) and NAC (right panel) suppressed the PA-induced JNK activation/phosphorylation in HepG2 cells. Results in (<b>A</b>), (<b>B</b>), and (<b>C</b>) are presented as mean ± SD, *P<0.05 versus control, ^&P<0.05 NAC versus TO, ^#P<0.05 versus PA.…”

Preventable deaths in childhood, according to actions of the Unified Health System, Brazil by Deborah Carvalho Malta (634594)

“…Results: In Brazil, preventable death rates (5.1% per year) had a higher decrease compared with non-preventable ones (2.5% per year). …”

Imaging setup and step parameters. by César S. Mendes (650719)

DataSheet1_Rational Design of Synergistic Structure Between Single-Atoms and Nanoparticles for CO2 Hydrogenation to Formate Under Ambient Conditions.DOCX by Shengliang Zhai (10960983)

“…Moreover, as a heterogeneous catalyst, this hybrid catalyst is easily recovered and exhibits about a 20% decrease in the catalytic activity after five cycles. …”

DataSheet_1_Polysaccharides From the Roots of Millettia Speciosa Champ Modulate Gut Health and Ameliorate Cyclophosphamide-Induced Intestinal Injury and Immunosuppression.pdf by Xiaogang Chen (317265)

“…Meanwhile, MSCP restored intestinal morphology, increased the ratio of villus height/crypt depth (V/C), and improved the number of goblet cells and mucins expression. …”

Table_1_Polysaccharides From the Roots of Millettia Speciosa Champ Modulate Gut Health and Ameliorate Cyclophosphamide-Induced Intestinal Injury and Immunosuppression.pdf by Xiaogang Chen (317265)

“…Meanwhile, MSCP restored intestinal morphology, increased the ratio of villus height/crypt depth (V/C), and improved the number of goblet cells and mucins expression. …”

Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. by Krisztina Tóth (12009827)

“…<p><b>(A)</b> NKCC1 mRNA expression levels in newborn and adult microglia isolated from C57BL/6J mice compared to neural progenitors derived from E17 embryonic hippocampi. …”

Hexokinase 2 (Hxk2) is the main 2DG-phosphorylating enzyme <i>in vivo</i>. by Clotilde Laussel (13237429)

“…Values are normalized to the value of the WT / 15 min (n = 3 independent experiments ± SEM, <i>p</i>value indicated, paired <i>t</i>-test) (<b>B</b>) 2DG causes a decrease in ATP content as visualized using a FRET ATP biosensor. …”

The role of TCTP and CSN4 in the control of CULLIN neddylation and cell proliferation is conserved in <i>Drosophila</i>. by Léo Betsch (6273707)

“…CSN4^k08018 mutant clones in which p35 is overexpressed (CSN4-/-, lower panels) still show loss or diffuse GFP staining in mutant clone. Bars = 5μm. (<b>c-e</b>) CSN4 mutant photoreceptors show a delay in the acquisition of neuronal identity but not in caspase staining. …”

BODIPY-cholesterol efflux from fibroblasts is affected by ShhN. by Michel Bidet (206600)

“…<p>BODIPY-cholesterol induces the accumulation of Smo in the plasma membrane as cholesterol (A). Plasma membrane enriched fractions from control NIH 3T3 (A, lane 1), NIH 3T3 treated for 6 h with 30 nM ShhN (A, lane 2), and NIH 3T3 treated for 3 h with 2.5 µM BODIPY-cholesterol (A, lane 3) were prepared for immunoblotting with antibodies against Smo. …”

Circular dichroism data. by Ney Ribeiro Leite (368966)

“…<p>Near-UV CD spectra of AaegOBP1 at pH 7 (blue trace) and pH 5.5 (green trace). Disruption of hydrogen bonds that keep the C-terminus covering the binding pocket may account for the changes in the environment of aromatic residues (Phe, Tyr, and/or Trp) at low pH and consequently the decrease in amplitude.…”

Characteristic dynamics of highly protected parameter sets. by Peter T. McHale (615341)

“…(S5)) in the asymmetric population (C), but frequently fluctuates down to zero in the symmetric case (D). …”

Deletion of <i>hfq</i> impacts central metabolism. by Irnov Irnov (282410)

“…<p>(A) Heatmap showing the changes in the level of various metabolites among the WT, Δ<i>hfq</i>, Δ<i>hfq vor</i>::Tn<i>5</i>, and <i>vor</i>::Tn<i>5</i> strains, as measured by LC-MS. …”

Conditional inactivation of the <i>Nsun4</i> gene in heart and skeletal muscle. by Metodi Dimitrov Metodiev (586330)

“…<p>A. Decreased lifespan of mice with a muscle-specific knockout of <i>Nsun4</i>. …”

Measurements of Sycp3 vs. by Yana P. Blokhina (6239588)

“…C: Numbers of engaged telomeres per cell, where one engaged telomere end is an Sycp3 line with its telomere associated with a potentially non-homologous telomere end. …”

Data_Sheet_1_Health-related heterogeneity in brain aging and associations with longitudinal change in cognitive function.docx by Jo Wrigglesworth (6563171)

“…Among resilient brain agers, class 1 was associated with a decrease in cognition, and class 2 with an increase over 5 years, though was a small effect that was equivalent to a 0.04 standard deviation difference per year. …”

The transient K⁺ currents displayed sensitivity towards holding potentials, and the magnitude changes during development. by Snezana Levic (336804)

“…(<b>C</b>) Mean difference current density at +0 mV at apical and basal regions of the basilar papilla (pA/pF) at E8, E10, E12, E16, and P2. …”