Statin Intensity and Clinical Outcome in Patients with Stable Coronary Artery Disease and Very Low LDL-Cholesterol by Soo Youn Lee (3186723)

“…</p><p>Results</p><p>Group 1 and group 2 consisted of 181 patients (40.3%) and 268 patients (59.7%), respectively. The mean LDL-C level decreased to 52 and 57 mg/dL in group 1 and group 2, respectively, during follow-up. …”

The computational model can explain impaired glucose homeostasis and β-cell dysfunction under varying glycemic conditions in HepaRG liver-islet MPS. by Belén Casas (5906522)

“…Model uncertainty is depicted as shaded areas in panels <b>A-E</b>. Data in panels <b>A-B</b> are presented as mean ± SEM, n = 5. n: Number of platform replicates included in the experiment.…”

Epigenetic regulation of EndMT mediated by loss of ERG/FLI1. by Nao Nagai (6034187)

“…The regions where the H3K27Ac level is significantly decreased after siERG+siFLI1 treatment are marked with a dagger (†). …”

Motor activity defects in old Gas7-deficient mice. by Bo-Tsang Huang (162584)

“…In contrast, the time before falling decreased significantly for old Gas7-deficient mice compared to old wild-type mice (n  = 15 each). …”

Image2_Using electronic admission data to monitor temporal trends in local medication use: Experience from an Australian tertiary teaching hospital.tif by Richard J. Woodman (8830580)

“…</p><p>Results: Of the 692,522 total admissions, 300,498 (43.4%) had at least one recorded medication. The overall mean number of medications for patients that were medicated increased steadily from a mean (SD) of 5.93 (4.04) in 2007 to 7.21 (4.98) in 2018. …”

Image3_Using electronic admission data to monitor temporal trends in local medication use: Experience from an Australian tertiary teaching hospital.tif by Richard J. Woodman (8830580)

“…</p><p>Results: Of the 692,522 total admissions, 300,498 (43.4%) had at least one recorded medication. The overall mean number of medications for patients that were medicated increased steadily from a mean (SD) of 5.93 (4.04) in 2007 to 7.21 (4.98) in 2018. …”

Image4_Using electronic admission data to monitor temporal trends in local medication use: Experience from an Australian tertiary teaching hospital.tif by Richard J. Woodman (8830580)

“…</p><p>Results: Of the 692,522 total admissions, 300,498 (43.4%) had at least one recorded medication. The overall mean number of medications for patients that were medicated increased steadily from a mean (SD) of 5.93 (4.04) in 2007 to 7.21 (4.98) in 2018. …”

Image1_Using electronic admission data to monitor temporal trends in local medication use: Experience from an Australian tertiary teaching hospital.pdf by Richard J. Woodman (8830580)

“…</p><p>Results: Of the 692,522 total admissions, 300,498 (43.4%) had at least one recorded medication. The overall mean number of medications for patients that were medicated increased steadily from a mean (SD) of 5.93 (4.04) in 2007 to 7.21 (4.98) in 2018. …”

Table1_Using electronic admission data to monitor temporal trends in local medication use: Experience from an Australian tertiary teaching hospital.docx by Richard J. Woodman (8830580)

“…</p><p>Results: Of the 692,522 total admissions, 300,498 (43.4%) had at least one recorded medication. The overall mean number of medications for patients that were medicated increased steadily from a mean (SD) of 5.93 (4.04) in 2007 to 7.21 (4.98) in 2018. …”

Snail regulates RELN expression in ESCC cells. by Yi Yuan (180239)

“…<p><b>A&B</b>: Snail protein was increased (<b>A</b>) and RELN mRNA was decreased (<b>B</b>) in a time-dependent manner after 5 ng/ml TGF-β1 treatment in KYSE-510 cells. β-actin served as the loading control in Western blot. …”

Expression of BMPs and their endogenous inhibitors during progression and reversal of chronic kidney disease. by Anne-Cécile Huby (5653777)

“…<p>Quantitative RT-PCR analysis of BMP6 (A) and BMP7 (B) and their endogenous inhibitors noggin (C) and USAG-1 (D) in the renal cortex of wild type and RenTg mice before and after irbesartan treatment. …”

FFA- induced dysfunction and apoptosis of NIT-1 cells. by Huiping Yuan (358233)

“…<p>Palmitate and oleate (0.5 mmol/L, 48 h) decreased glucose-stimulated insulin secretion (GSIS, 20 mmol/L D-glucose in KRBH) (A), reduced insulin mRNA level shown by real-time PCR (B), induced apoptosis assessed by double-staining with Annexin V and PI (C) and increased lipid accumulation detected by Oil Red O Staining in NIT-1 cells (D). …”

supplyment figure 1 for article by Wenlong Xue (7413242)

“…<p><b>The efficiency of</b> <b>miR-126-3p silencing, CSE and DNMT1 overexpression or DNMT1 silencing.</b> (a) miR-126-3p antagomir transfection decreased miR-126-3p expression by 74% in HUVECs compared with control. n = 6. …”

Effects of METH self-administration on monoamine levels in the striatum. by Irina N. Krasnova (223517)

“…<p>METH caused persistent decreases in striatal DA levels (A), which negatively correlated with total drug intake when data at 24 hours, 7 and 14 days after cessation of self-administration were combined (B) and at 14 days post-drug (C). …”

Gene expression levels of the intracellular localized TLRs <i>Tlr3</i>, <i>Tlr7</i>, <i>Tlr8</i>, and <i>Tlr9</i> in different HF models of diverse etiology. by Peter Moritz Becher (192666)

“…In the heart failure model caused by chronic AngII-infusion for 21 days (shown in yellow) only the intracellular localized <i>Tlr3</i> displayed a significant decrease when compared to their controls. …”

Table_1_Gastrointestinal digestibility insights of different levels of coated complex trace minerals supplementation on growth performance of yellow-feathered broilers.DOCX by Chuanbin Chen (11385608)

“…The VH to crypt depth (CD) ratio (V/C) of jejunum and ileum in the CCTM400 and CCTM600 groups was higher (P < 0.05) than that in the CCTM1000 group. …”

Autocrine SDF-1 signaling determines vasculogenicity of CPC clones in vitro. by Claudia O. Rodrigues (208704)

“…Clones were stably transfected with one of three different SDF-1 shRNAs (D8, E1 and H7) or a scrambled control (NS). C. Exogenous SDF-1 increased mean tube number in both weak (CL3 and CL20) and strong (CL22 and 42A1) tube forming clones, and AMD3100 decreased tube number in strong tube formers (CL22, CL42A1). …”

Structural homology models of hGPR83 in putative complexes with arrestin and G-protein. by Anne Müller (103420)

“…<p><b>A)</b> The presented structural hGPR83-arrestin complex homology model (backbone cartoon) is mainly based on the crystal structure of rhodopsin with bound arrestin (PDB entry 5DGY, [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0168260#pone.0168260.ref043" target="_blank">43</a>]), which served as a template for modeling procedures. …”

Effect of Hoechst 3342 and FCCP on MMPT as determined by JC1, DiOC₆-3 or Rho 123 in K562 cells. by J. Mario Wolosin (465629)

“…Note that the SP and nonSP shift in opposite direction along the orange axis. <b>C.</b> K562 cell cultures (0.2 x 10⁶ cells/ml) were incubated with 5 nM DiOC₆-3 for 20 min or 100 nM Rho123 for 60 min. …”

Siglec-1 expressed in LPS mDCs capture distinct ganglioside containing vesicles, such as HIV-1 viral-like particles, liposomes, and exosomes. by Nuria Izquierdo-Useros (91232)

“…Of note, Siglec-14 shares 100% of amino acid homology with Siglec-5 in the V-set domain. Data show mean values and SEMs from three experiments including cells from nine donors. …”