Inhibition of N-WASP activation suppresses de novo actin polymerization and reduces the quantal release of transmitters. by María José Olivares (573505)

“…<p>(<b>A–B</b>) ACCs were permeabilized in the presence of 10 µM free Ca²⁺ and 5 µM of the N-WASP inhibitor wiskostatin (Wsk), or the vehicle DMSO. …”

Dynlt1 alters the intracellular localization of OX1R following ligand-induced internalization. by David Duguay (216295)

“…Equal transfection of Myc-Dynlt1 was verified by IB with anti-Myc antibody on cell extracts (input). (<b>C, D</b>) HEK293 cells stably expressing OX1R-GFP were transfected with control plasmid (<b>C</b>) or pCS2-FLAG-Dynlt1 (<b>D</b>), stimulated with OX-A for 5–30 min or left un-stimulated (0 min) and analyzed by fluorescent microscopy. …”

Table_1_Improving Mood and Cognitive Symptoms in Huntington's Disease With Cariprazine Treatment.DOCX by Maria Judit Molnar (7609673)

“…Cariprazine treatment resulted in the following changes from BL to week 12, respectively: the mean score of BDI decreased from 17.7 ± 10.7 to 10.0 ± 10.7 (p <0.0097), while the Behavioral Assessment score of the UHDRS decreased from 54.9 ± 11.3 to 32.5 ± 15.4 (p < 0.0001); ACE score increased from 75.1 ± 11.0 to 89.0 ± 9.3 (p < 0.0001); Cognitive Verbal Fluency score from 6.2 ± 2.5 to 7.7 ± 2.7 (p < 0.0103); Symbol Digit Test from 9.2 ± 6.9 to 12.3 ± 8.9 (p < 0.0009). …”

LGG-1 foci formation following UV irradiation in hermaphrodite and male gonads. by Hyemin Min (6733586)

“…The non-irradiated gonad appeared not different from the one at the 0.5 h time point. (4 h) The number of LGG-1 foci decreased compared to the 3 h time point, and PGL-1 was removed from a significant number of germ cells (arrowheads) in the UV-irradiated gonad. …”

COMPARISON OF RESPONSE SURFACE METHODOLOGY (RSM) AND ARTIFICIAL NEURAL NETWORKS (ANN) TOWARDS EFFICIENT OPTIMIZATION OF FLEXURAL PROPERTIES OF GYPSUM-BONDED FIBERBOARDS by Morteza Nazerian (5256530)

“…The weight ratios of fiberglass (at three levels 0, 3 and 6%), bagasse fiber (at three levels 0, 7.5 and 15%) and kenaf fiber (at three levels 0, 7.5 and 15%) to gypsum are used to make the gypsum-bonded fiberboard with the nominal density 1.10 g.cm-3 . …”

Intracellular Ca²⁺ concentration, ER calcium flux and collagen analysis. by Laura Leoni (11495393)

“…(F) Representative SDS-PAGE autoradiography of ³H-collagen type I extracted from control hFOB untrasfected cells (C), KO (A3, A12, A6 and C5) and WT (A4) clones. …”

Demography of normoxic and hypoxic flies by Paul Vigne (373124)

“…</p> <p>(A) Survivorship analysis.</p> <p>Hypoxia decreased the mean life span from 33.6±0.8 days (n = 79) to 6.3±0.1 days (n = 282).…”

Estradiol, GPER agonist G1, and GPER antagonist G15 affect cell proliferation in the hippocampus. by Paula Duarte-Guterman (754981)

“…For Experiment 1 (C-D), rats were given either estradiol (E2, 10 μg), one of the doses of G1 (M, medium, 5 μg; H, high, 10 μg) or one of the vehicles (oil or DMSO). …”

Expansion of beta-cell mass is impaired in RIPCre⁺Survivin^fl/fl mice after PDL. by Xiaohong Wu (147036)

“…(b) The increment of beta-cell number in the pancreas tail at PDL day 7 is markedly attenuated in the mutant mice compared with that in controls (n = 5 per genotype). (c) Beta-cell size is decreased in the pancreas tail of the mutant mice at PDL day 7 compared with that in sham-operated pancreas tail, but is still larger than that in PDL-treated controls (n = 5 per genotype). …”

Isoflurane transiently increases CD73 activity without changing CD73 synthesis in cultured endothelial cells. by Mihwa Kim (580181)

“…<p>A. Human umbilical vein endothelial (EA.hy926) cells treated with 2.5% isoflurane showed a significant but transient induction of CD73 activity. …”

TOP1α and UPF1 directly repress <i>TTG2</i>. by Chengxiang Li (5278343)

“…The data underlying this figure are included in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000930#pbio.3000930.s011" target="_blank">S1 Data</a>. 3C, chromatin conformation capture; ChIP, chromatin immunoprecipitation; CPT, camptothecin; DRIP, DNA:RNA hybrid immunoprecipitation; GUS, β-glucuronidase; HA, hemagglutinin; ND, not detectable; qPCR, quantitative PCR; WT, wild-type plants.…”

Supplementary Material for: Analysis of Stroke Burden in China from 1990 to 2021 and Projections for the Next Decade by Li X. (3218241)

Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse by Ahmedna, Mohamed

“…Results show that cell viability decreased to 93 ± 3%, 83 ± 6%, 65 ± 4% and 39 ± 3% at 10, 25, 50 and 100 mM of glucose on day 1 with further drastic decrease in cell viability to 73 ± 5%, 61 ± 3%, 35 ± 2%, and 11 ± 6%, respectively, on day 4 compared to the untreated cell. …”
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Reduction in DRG neuronal numbers following error correction. by Ayal Ben-Zvi (438134)

“…A significant decrease in neuron number is observed in the Sema3A^−/−:BAX^−/− embryos as compared to Sema3A^+/+: BAX^−/−, which correlates with error correction (P = 0.0169). …”

Cleavage site of caspase-1-like protein and the presence of proPO-casp fragments in plasma and the plasma PO activity after bacterial injection. by Miti Jearaphunt (550257)

“…The statistical analysis was performed using one-way ANOVA. * <i>P</i><0.05, significant difference compared with the 0 h time point, ^##<i>P</i><0.01, significant difference compared with the 3 h time point. The values shown in (C) are mean of five samples and the bars indicate SEM.…”

An <i>Smc1b</i> hypomorphic mutation affects synapsis and recombination. by Brenda Murdoch (47263)

“…(B) Similarly, mean genome-wide MLH1 values ± SE were markedly decreased in homozygotes (20.7.9±0.21) by comparison with controls and heterozygotes (27.3±0.32 and 26.5±0.33, respectively) (F = 118.2; <i>p</i><0.0001). …”

Carnosine treatment has sub-maximal effect in counteracting memory deficits in 3xTg-AD mice. by Carlo Corona (354704)

“…Carnosine-fed mice showed a trend toward decreased long-term memory deficit. …”

Figure 3 from Repurposing Amiodarone for Bladder Cancer Treatment by Francisco J. Roa (21479153)

“…<p>Amiodarone decreases colony formation capacity in bladder cancer cell lines. …”

Table_1_Effect of the Depth of Cold Water Immersion on Sleep Architecture and Recovery Among Well-Trained Male Endurance Runners.DOCX by Maxime Chauvineau (10502972)

“…<p>Introduction: The aim of the present study was to investigate the effect of the depth of cold water immersion (CWI) (whole-body with head immersed and partial-body CWI) after high-intensity, intermittent running exercise on sleep architecture and recovery kinetics among well-trained runners.</p><p>Methods: In a randomized, counterbalanced order, 12 well-trained male endurance runners (V.O₂max = 66.0 ± 3.9 ml·min⁻¹·kg⁻¹) performed a simulated trail (≈18:00) on a motorized treadmill followed by CWI (13.3 ± 0.2°C) for 10 min: whole-body immersion including the head (WHOLE; n = 12), partial-body immersion up to the iliac crest (PARTIAL; n = 12), and, finally, an out-of-water control condition (CONT; n = 10). …”

<b>The Influence of Pre-Exposure to Marine Heatwaves on the Critical Thermal Maxima (CT</b>_{<strong>max</strong>}<b>) of Marine Foundation Species</b> by Nathan King (8559951)