Chronic High Fructose Intake Reduces Serum 1,25 (OH)₂D₃ Levels in Calcium-Sufficient Rodents by Veronique Douard (549533)

“…Replacing glucose with fructose prevented these increases in Ca²⁺ transporter, CYP27B1, and 1,25(OH)₂D₃ levels induced by a low Ca²⁺ diet. In adult mice fed for three mo a normal Ca²⁺ diet, renal expression of CYP27B1 and of CYP24A1 (24-hydroxylase) decreased and increased, respectively, when the carbohydrate source was fructose instead of glucose or starch. …”

Transwell data by Pai Pang (5361815)

“…Transwell migration assay and Martrigel invasion assay showed that an ectopic increased level of miR-92b could raise the migration and invasion ability of PCI-37A cells, while a reduced level of miR-92b led to a significant decrease in the number of migrating or invasive cells.After knocked down with SP1 expression, PCI-37A/B cells showed a significant decrease in migration and invasion. …”

Mouse phenotyping identified 200 BMD genes. by Anna L. Swan (9922965)

“…<p>(A) Of the 3,823 genes deleted in mice, 200 or 5% caused a change in BMD phenotype. …”

Global proteomic changes upon perturbation of Hsp90. by Teresa R. O’Meara (720286)

“…Non-denaturing IEX fractionation and MS experiments were performed on <i>lys2Δ/lys2Δ tetO-HSP90/hsp90Δ</i> cells that were untreated, treated with DOX to repress <i>HSP90</i> expression, or treated with 15 μM GdA to inhibit Hsp90 function. For DOX treatment, cells were treated with 0.05 μg/mL DOX overnight and then subcultured into medium with 5 μg/mL DOX for 4 hours before harvesting. …”

MSR algorithm analysis. by Federico Comoglio (224744)

“…(B) The mean move length significantly decreases as a function of the protein length. …”

<i>apol1</i> interacts with <i>myh9</i> in an anemic context. by Blair R. Anderson (765261)

“…<p>To test for epistatic effects of <i>apol1</i> and <i>myh9</i> in zebrafish, we first co-injected both <i>apol1-</i>MO (1.0ng/nl dose) and <i>myh9-</i>MO (6.0ng/nl dose) into zebrafish larvae and scored for edema formation at 5 dpf. …”

Degradation Pathways of Ataxin-3-Induced Neurodegeneration by Julide Bilen (35807)

“…Genotypes (B) <i>EP1384; gmr-GAL4 UAS-SCA3trQ78 /+; UAS-DTS5/+</i> and (C) <i>w; gmr-GAL4 UAS-SCA3trQ78/+; UAS-DTS5/E213-1A.…”

Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes by Zhaoyun Jiang (15317737)

Evidence for rapid downward fecundity selection in an ectoparasite (Philornis downsi) with earlier host mortality in Darwin’s finches by Sonia Kleindorfer (95761)

“…Across a 12-year period, we observed a mean of ~17% P. downsi mortality in host nests with 55 ± 6.2 % host mortality, and a trend of ~66% higher host mortality throughout the study period. …”

IL-6Rα antibodies diminish anesthetic DILI in female BALB/c mice. by Joonhee Cho (399792)

“…(A) IL-6Rα antibodies administered days 0 and 7 diminished hepatitis as demonstrated by decreased inflammation/injury scores (1.6±0.1, mean ± SE) when compared to TFA-S100 – immunized, female , BALB/c mice not treated with IL-6Rα but administered phosphate buffered saline at the same time points (2.3±0.2, mean ± SE). …”

Early Wnt/β-catenin signaling enhances cardiac differentiation. by Sharon L. Paige (247316)

“…<p>(<b>A</b>) Quantitative RT-PCR on day 14 of differentiation shows induction of <i>β-MHC, cTnT and Nkx2.5</i> expression by activin A/BMP4 is attenuated with Dkk1. …”

Pdd1 dephosphorylation does not occur in by Annie Wan Yi Shieh (459701)

“…<div><p>Δ<i>LIA5 </i><b>conjugation </b><b>cells</b>.</p> <p>(A) anti-Pdd1 western blot analysis of total protein isolated from conjugating WT, <i>∆LIA5</i> and <i>∆DCL1</i> at indicated time point. …”

Swimming endurance training protocol. by Vítor S. Fernandes (21262991)

“…<i>Mib1</i>^<i>flox</i><i>;Tnnt2</i>^<i>Cre</i> cardiomyocytes also showed decreases in outward K⁺ peak currents and currents at the end of depolarizing pulses at potentials ≥−10 mV and ≥−20 mV, respectively, and this was accompanied by a lower charge density at ≥−20 mV. …”

Eigenvalue stability in the LHIGP module. by Amanda L. Caskenette (3692260)

“…<p>Patterns of stability for Cases 1–4 (a-d) starting from a food chain module and moving towards an exploitative competition module as <i>m</i> & <i>s</i> decrease from 1 to 0 (Parameter values: r = 1.5, K = 1, a_CR = 3, a_PC = 1, a_PR = 0.2, b_CR = 1.5, b_PC = 1, b_<i>PR</i> <i>= 1</i>, d_C = 0.3 (b and d), 0.5 (a and c), d_P = 0.1 (c and d), 0.15(a and b)).…”

Enhanced megakaryopoiesis and thrombopoieisis after DT-mediated MK ablation. by Catherine Angénieux (145933)

“…(<b>A</b>) PLT counts of saline- and DT-treated mice (n = 5 and 20, respectively) were measured on day 7 and 8. …”

Cooperatively coupled cargo translocation. by Aidan I. Brown (509994)

“…<p>(A) Cytosolic PEX5-cargo concentration vs. PEX5 cargo addition rate, . …”

Effects of cooperativity on effective energetic contribution of hotregions. by Rudi Agius (454506)

“…Effectively, the additive hotspot energy assumption results in hotregions contributing in a linearly increasing manner according to their size, the negative cooperativity assumption results in hotregions contributing in an increasing exponential-like manner as the hotregions increase in size, and the positive cooperativity assumption results in hotregions reaching a maximum contribution at around a hotregion size of 5, with their contribution decreasing beyond.…”

Distal cue novelty task. by Desiree R. Seib (5249750)

“…<p>A) Rats decreased exploration of the objects over the 6 trials (Mauchly’s test P = 0.2; trial effect, F_5,135 = 44, P<0.001, partial η² = 0.62) and did not increase exploration upon changes to the distal context on trial 6 (trial 6 vs trials 1–4 all P<0.01, trial 6 vs trial 5 P = 0.3). …”

FGFR1-Frs2/3 pathway is required for the specification of prosensory domain. by Kazuya Ono (513633)

“…<p>(A–C) p27^Kip1 (magenta) is expressed in the post-mitotic, BrdU (green) negative, prosensory domain (bracket) in sections of E14.5 cochlea (A). …”

Supramolecular Structures and Assembly and Luminescent Properties of Quinacridone Derivatives by Kaiqi Ye (1436131)

“…In contrast, high efficiencies (21.5−12.0 cd/A) are achieved for a wider dopant concentration range of 0.5−5.0% when Alq₃:<b>2</b> films are employed as emitting layer. …”