Deletion of Msh2 in medium-spiny neurons delays nuclear huntingtin phenotypes. A, B. by Marina Kovalenko (136557)

“…<p>Nuclear mutant huntingtin immunostaining is decreased in the striata of five-month old <i>HdhQ111</i>/+ mice with deletion of <i>Msh2</i> in MSNs. …”

Knockdown of IGFBP7 restored the TGF-β1-induced EMT in HRPTECs. by Jun Watanabe (403029)

“…HRPTECs were transfected with control or IGFBP7 siRNAs (25 nM final concentrations) and subsequently stimulated with TGF-β1 (2.5 ng/ml, 48 h). Lowering the expressions of IGFBP7 proteins reduced the TGF-β1-induced α-SMA expression, but failed to restore the TGF-β1-decreased E-cadherin expression. …”

Predicted growth rates for <i>S. bayanus</i> and <i>S. pombe</i> expression datasets. by Edoardo M. Airoldi (268357)

“…(A) Predicted growth rates for <i>S. bayanus</i> undergoing the diauxic shift from fermentative to respiratory growth (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000257#pcbi.1000257.s007" target="_blank">Table S3</a>). …”

Luminescent Hydrido-Carbonyl Clusters of Rhenium Containing Bridging 1,2-Diazine Ligands by Monica Panigati (1734016)

“…In the case of <b>4a</b>, a blue shift and an increase of the emission intensity were observed upon decreasing the solvent polarity.…”

<i>In vitro</i> data showing that IGF+HGF stimulation enhances Sca-1⁺/CD31⁻ cell survival and proliferation and protects co-cultured stressed HL-1 from apopto... by Xiaohong Wang (93777)

“…Data are presented as mean+/−SEM.</p>…”

Model sensitivity analysis to parameters: <i>k</i>_<i>τ</i>, <i>τ</i>_<i>max</i>, <i>F</i>_<i>p</i>, <i>F</i>_<i>c</i>, <i>K</i><sub><i>r</i... by Dharsan K. Soundarrajan (11632145)

“…<i>e</i>., 50% of a BV of 1.5 μM would simulate a value of 0.75 μM). …”

Ad26.COV2.S vaccination attenuates signatures of complement system activation and coagulation cascade associated with severe COVID-19. by Malika Aid (7303874)

“…<b>(B)</b> Heatmaps of the normalized expression of the leading genes contributing to the enrichment of thrombosis-associated pathways increased by SARS-CoV-2 in sham animals (in green) and decreased in Ad26 vaccinated hamsters (in pink and blue) at 4 dpi. …”

Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs. by Ignacio E. Schor (120406)

“…S5</a>). Orange boxes mark regions with peaks appearing at 2 h TSA and not further increasing, or even decreasing, at 6 h (MALAT1 peaks). …”

Peripheral Blood Proteins Distinguish IPF Patients from Controls by Ivan O Rosas (91093)

“…Every protein level was divided by the geometric mean of values for the same proteins for all patients and log based 2 transformed. …”

Factors associated to the practice of physical activity by Brazilian workers by Ana Marcia Rodrigues da Silva (6299831)

“…It is a descriptive, analytical, cross-sectional, quantitative study conducted with 82,019,207 workers by means of the National Survey by Household Sample of 2015. …”

The important variables for random forests (RF). by Deokjin Joo (476851)

“…<p>Two measures of accuracy and Gini index were plotted for each variable used for classification with random forests in a rank order from top to bottom. Meaning of abbreviations of shape variables: ProcCoord_5y, Procrustes <i>y</i> coordinate of landmark position 5; ProcCoord_2x, Procrustes <i>x</i> coordinate of landmark position 2; the number represents landmark position as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0077686#pone.0077686.s001" target="_blank">Figure S1</a>. …”

Supplementary Material for: Atypical Presentation of an Ovarian Yolk Sac Tumor in an 80-Year-Old Woman: A Case Report and Review of the Literature by Maldonado V. (14559080)

Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe... by Huiyu Xu (12255545)

“…A two-parameter logistic curve allowed translation of ovarian reserve scores into an “endocrine age” and enabled individualized prediction of future milestones, such as diminished reserve with ovarian score of 50 and perimenopause, the lowest ovarian reserve score in our ART population. …”

Data Sheet 2_Time-updated patterns of hemoglobin and hematocrit and the risk of CKD progression.docx by Li-zhe Fu (14825593)

“…We constructed Cox and group-based trajectory modeling (GBTM) models to examine Hb’s and HCT’s associations with short- and long-term risk of composite outcomes in patients with CKD stages 3–4.</p>Results<p>A total of 730 individuals were included, with a median age of 59.30 (48.47, 68.63) years, 306 (41.92%) were women, and median eGFR was 39.24 (26.26, 50.67) mL/min/1.73 m². …”

Table 1_Association of magnesium depletion score with serum anti-aging protein Klotho in the middle-aged and older populations.docx by Zhijie Zhuang (17669958)

“…</p>Results<p>The weighted average serum Klotho concentrations decreased significantly across MDS groups (low: 864.50, middle: 805.67, high: 755.02 pg.…”

<i>ab</i> cooperates with impaired Hippo pathway signalling to drive tumour overgrowth. by Nezaket Turkel (434914)

“…F-actin for cell morphology is in red. GFP (panels A–H), Elav (panels A′–D′), Dac (panels E′F′), Eya (panels G′H′), and merges (panels A″–H″). …”

DataSheet_1_New insights into β-glucan-enhanced immunity in largemouth bass Micropterus salmoides by transcriptome and intestinal microbial composition.docx by Yuexing Zhang (11909)

“…Four experimental diets were designed with β-glucan supplementation levels of 0 (control), 100 (LA-100), 200 (MA-200), and 300 (HA-300) mg kg^-1, and each diet was fed to largemouth bass (79.30 ± 0.50 g) in triplicate for 70 days, followed by a 3-day challenge experiment. …”

Image 4_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

HAS inhibition in HepR21 leads to ROS surge, decline in HA level and upregulated MAP-LC3 levels. by Paramita Saha (473954)

“…<p>[A] <b><i>Inhibition of HA synthesis led to increased generation of ROS</i></b><b>—</b> HepR21 cells subjected to treatment with different concentrations of HA synthetase inhibitor, 4-MU and untreated cells were assayed for ROS. 4-MU treatment resulted in excess generation of ROS as a function of time and concentration. …”

Supplementary file 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.docx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”