Image_1_Efficacy and safety of Iguratimod as an add-on therapy for refractory lupus nephritis: A preliminary investigational study.pdf by Qingran Yan (637573)

“…The CRR rate was 42.3% (11/26) at month 6. With a median follow-up of 52 weeks (range: 23-116 weeks), the CRR rate at the last visit was 50% (13/26) and 73.1% (19/26) of patients had UPCR decrease of over 50%. …”

Discovery of Novel Thiophene-Based Baloxavir Derivatives as Potent Cap-Dependent Endonuclease Inhibitors for Influenza Treatment by Yongzhi Chen (172975)

“…Among them, <b>ATV2301</b> exhibited an excellent anti-influenza activity (EC₅₀, H1N1 = 1.88 nM, H3N2 = 4.77 nM), a higher safety index (SI, H1N1 = 18218, H3N2 = 7180), and a remarkably improved oral bioavailability (<i>F</i> = 71.60%). …”

Discovery of Novel Thiophene-Based Baloxavir Derivatives as Potent Cap-Dependent Endonuclease Inhibitors for Influenza Treatment by Yongzhi Chen (172975)

“…Among them, <b>ATV2301</b> exhibited an excellent anti-influenza activity (EC₅₀, H1N1 = 1.88 nM, H3N2 = 4.77 nM), a higher safety index (SI, H1N1 = 18218, H3N2 = 7180), and a remarkably improved oral bioavailability (<i>F</i> = 71.60%). …”

Data_Sheet_1_The influence of precipitation timing and amount on soil microbial community in a temperate desert ecosystem.pdf by Yao Xiao (227567)

“…The study included five precipitation pattern treatments: a control group (C), as well as groups receiving 50 and 100% of the local mean annual precipitation amount (145 mm) during either the early growing season (E50 and E100) or the late growing season (L50 and L100). …”

Cooperative Spin Crossover and Order−Disorder Phenomena in a Mononuclear Compound [Fe(DAPP)(abpt)](ClO₄)₂ [DAPP = [Bis(3-aminopropyl)(2-pyridylmethyl)amine],... by Galina S. Matouzenko (2470315)

“…The synthesis and detailed characterization of the new spin crossover mononuclear complex [Fe^II(DAPP)(abpt)](ClO₄)₂, where DAPP = [bis(3-aminopropyl)(2-pyridylmethyl)amine] and abpt = 4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole, are reported. …”

Cooperative Spin Crossover and Order−Disorder Phenomena in a Mononuclear Compound [Fe(DAPP)(abpt)](ClO₄)₂ [DAPP = [Bis(3-aminopropyl)(2-pyridylmethyl)amine],... by Galina S. Matouzenko (2470315)

“…The synthesis and detailed characterization of the new spin crossover mononuclear complex [Fe^II(DAPP)(abpt)](ClO₄)₂, where DAPP = [bis(3-aminopropyl)(2-pyridylmethyl)amine] and abpt = 4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole, are reported. …”

Cooperative Spin Crossover and Order−Disorder Phenomena in a Mononuclear Compound [Fe(DAPP)(abpt)](ClO₄)₂ [DAPP = [Bis(3-aminopropyl)(2-pyridylmethyl)amine],... by Galina S. Matouzenko (2470315)

“…The synthesis and detailed characterization of the new spin crossover mononuclear complex [Fe^II(DAPP)(abpt)](ClO₄)₂, where DAPP = [bis(3-aminopropyl)(2-pyridylmethyl)amine] and abpt = 4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole, are reported. …”

Differences in total Tau and p-Tau Thr231 following maternal Pg-OMV exposure. by Adrienne J. Bradley (20861948)

“…<p><b>(A</b>-<b>B)</b> Representative images of WB showing total Tau and p-Tau Thr231 Tau from E18.5 pup brains. <b>(C-D)</b> Quantification of western blots showing decrease in total Tau and increase in p-Tau Thr231 (Student’s T-Test p =  0.0013). …”

Quantification of neurotransmitters in rat’s complete brain tissue. by Hammad Ismail (4227988)

Supplemental figure S3 from Movements and residency of Caribbean reef sharks at a remote atoll in Belize, Central America by Ivy E. Baremore (11204064)

Confirmation of berberine by FTIR and NMR. by Hammad Ismail (4227988)

Fig 5 - by Katharina Riebenbauer (10726250)

NCOA4 is downregulated in human CCA tissues and is correlated with poor prognosis. by Wenlong Shen (9313937)

OCA inhibits the colony formation capacity of iCCA cells. by S. Di Matteo (6260417)

“…<p>After 10 days of culture, mixed and mucinous iCCA colonies were stained with 0.1% crystal violet and counted (a colony was considered a cluster of at least 50 cells). a) Photographs (magnification 1x) show representative wells in which mixed and mucinous iCCA colonies appear as a violet dot. …”

CD74 mediates the cross-talk between DC and B cells, enhancing immunosuppression in the TME. by Bianca Pellegrino (20314999)

Pro-inflammatory cytokine changes in the amnion. by Natasha Singh (9706948)

Pro-inflammatory cytokine changes in the decidua basalis. by Natasha Singh (9706948)

Climate and seed size of a dry forest species: influence on seed production, physiological quality, and tolerance to abiotic stresses by Samara Elizabeth Vieira Gomes (4718994)

“…The predicted increase in temperature will not impair germination, however, the time available for seedling establishment will decrease due to lacking rainfall. The increase in the amount of small-sized seeds produced in drought years is a strategy for coping with harsh environments, rather than a decrease in seed quality.…”

Exploring reopening strategies for low disease transmission <i>v</i>_<i>r</i> with testing capacity. by Mackenzie Dalton (14093874)

Over-expression of <i>Atg1</i> in the gut, fat body and Malpighian tubules extends lifespan. by Ivana Bjedov (75652)

“…(E) Expression levels of <i>Atg1</i> in the intestine and fat body driven by <i>HRGAL4</i> and <i>CSGAL4</i>, as determined by qRT-PCR normalised to <i>actin5C</i>. Data are means ±SEM of n = 3 samples. Statistical significance was determined by a one-way ANOVA Student’s <i>t</i>-test (*, p<0.05; **, p<0.01; ***, p<0.001). …”