Showing 12,021 - 12,040 results of 43,729 for search '(( 5 ((nn decrease) OR (mean decrease)) ) OR ( 50 ((teer decrease) OR (a decrease)) ))', query time: 0.65s Refine Results
  1. 12021

    An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos by Sergio Jarque (5698859)

    Published 2018
    “…<div><p>The knowledge on environmentally relevant chemicals that may interfere with thyroid signaling is scarce. Here, we present a method for the screening of goitrogens, compounds that disrupt the thyroid gland function, based on the automatic orientation of zebrafish in a glass capillary and a subsequent imaging of reporter gene fluorescence in the thyroid gland of embryos of the transgenic zebrafish line tg(tg:mCherry). …”
  2. 12022
  3. 12023
  4. 12024
  5. 12025

    Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 by María Dolores Moya-Garzón (5597540)

    Published 2018
    “…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”
  6. 12026

    Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 by María Dolores Moya-Garzón (5597540)

    Published 2018
    “…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”
  7. 12027

    Potency and breadth of subject immune sera. by Chad D. Nix (8704143)

    Published 2020
    “…The plot for each serum shows the proportion of viruses neutralized by FRNT<sub>50</sub> at a given serum dilution. Each step in each plot represents an FRNT<sub>50</sub> value for one virus; as fold serum dilution increases for each serum, the proportion of viruses neutralized decreases by 1/11 (9.1%) as each FRNT<sub>50</sub> dilution for each virus is crossed. …”
  8. 12028

    Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C<sup>∧</sup>N‑Chelated and Pyridine Ligands by Zhe Liu (77240)

    Published 2015
    “…The monodentate py ligands blocked hydrolysis; however, antiproliferative studies showed that all the Ir compounds are highly active toward A2780, A549, and MCF-7 human cancer cells. In general the introduction of an electron-donating group (e.g., Me, NMe<sub>2</sub>) at specific positions on the pyridine ring resulted in increased antiproliferative activity, whereas electron-withdrawing groups (e.g., COMe, COOMe, CONEt<sub>2</sub>) decreased anticancer activity. …”
  9. 12029

    Table_3_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.XLSX by Tiantian Zhu (8254053)

    Published 2021
    “…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”
  10. 12030

    Image_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.TIF by Tiantian Zhu (8254053)

    Published 2021
    “…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”
  11. 12031

    Table_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.docx by Tiantian Zhu (8254053)

    Published 2021
    “…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”
  12. 12032

    Table_2_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.xlsx by Tiantian Zhu (8254053)

    Published 2021
    “…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”
  13. 12033

    Structure and Bonding Properties of the Complex (η<sup>5</sup>-Diphenylfulvene)Mn(CO)<sub>3</sub><sup>+</sup> by Martin A. O. Volland (3077121)

    Published 2000
    “…Reaction of cymantrene (<b>6</b>) with <i>n</i>-butyllithium followed by benzophenone and subsequent hydrolysis yielded 1-(diphenylhydroxymethyl)(η<sup>5</sup>-cyclopentadienyl)(tricarbonyl)manganese (<b>7</b>). …”
  14. 12034

    Transgenerational hormetic effects of sublethal dose of flupyradifurone on the green peach aphid, <i>Myzus persicae</i> (Sulzer) (Hemiptera: Aphididae) by Qiuling Tang (495407)

    Published 2019
    “…<i>persicae</i> with a 48 h LC<sub>50</sub> of 8.491 mg/L. Using the age-stage two-sex life table approach, we assessed the effects of LC<sub>25</sub> of flupyradifurone on adult <i>M</i>. …”
  15. 12035

    5‑Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes by Hsueh-Yun Lee (141907)

    Published 2018
    “…<i>N</i>-Hydroxy-4-((5-(4-methoxybenzoyl)-1<i>H</i>-indol-1-yl)­methyl)­benzamide (<b>6</b>) has potent inhibitory selectivity against histone deacetylase 6 (HDAC6) with an IC<sub>50</sub> value of 3.92 nM. It decreases not only the level of phosphorylation of tau proteins but also the aggregation of tau proteins. …”
  16. 12036

    Effects of Sediment Characteristics on the Toxicity of Chromium(III) and Chromium(VI) to the Amphipod, <i>Hyalella azteca</i> by John M. Besser (467734)

    Published 2004
    “…Waterborne Cr(VI) caused reduced survival of amphipods with a median lethal concentration (LC<sub>50</sub>) of 40 μg/L. …”
  17. 12037
  18. 12038
  19. 12039

    Effects of LL-23, LL-23V9 or GI-20 on replication of Cal09 or NY01 in various cell types. by Shweta Tripathi (591806)

    Published 2015
    “…LL-23 (11μM) caused significant increase in replication of Cal09 in SAE cells. Results are mean±SEM of 4 or more experiments. * indicates a significant decrease in viral foci (p<0.05) compared to control. ** indicates a significant increase in viral foci (p<0.01) compared to control.…”
  20. 12040

    Table S5 from Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes by Andriy Marusyk (72192)

    Published 2023
    “…For continuous data, increase or decrease of at least 5% of initial value used as a threshold. …”