Preclinical Evaluation of ¹³¹I/¹⁸F‑Labeled Covalent Small-Molecule Inhibitors for STING Status Imaging by Jianyang Fang (11301298)

“…The affinity and specificity of tracers were assessed through cell uptake and docking experiments, demonstrating that [¹³¹I]I-NFIP exhibited high specificity for STING, with a cell-based IC₅₀ value of 7.56 nM. …”

Preclinical Evaluation of ¹³¹I/¹⁸F‑Labeled Covalent Small-Molecule Inhibitors for STING Status Imaging by Jianyang Fang (11301298)

“…The affinity and specificity of tracers were assessed through cell uptake and docking experiments, demonstrating that [¹³¹I]I-NFIP exhibited high specificity for STING, with a cell-based IC₅₀ value of 7.56 nM. …”

Desquamation area of the cecal mucosal layer in 57-week-old mice infected with <i>K</i>. <i>pneumoniae</i> is reduced by administering Gas6 recombinant protein. by Hitoshi Tsugawa (296864)

Trends in ESR per survey round by age group. by Alex Daama (18351052)

“…Across the first three surveys, ESR prevalence was consistently higher among the married participants than the never married participants, aPR = 1.83, 95% CI: [1.30,2.57]; aPR = 2.46, 95% CI: [1.50,4.06]; aPR = 2.22, 95% CI: [1.22,4.03]. …”

H3.3 variant diffuse midline glioma, H3K27-altered in a 28-year-old woman. by Ryo Kurokawa (9395874)

Model for regulation of <i>Drosophila</i> katanin by its non-catalytic domains. by Kyle D. Grode (725568)

Scallop fishery landings from RCP8.5 (top panel) and RCP4.5 (bottom panel) under the highest management strategy (catch limits, variable reference points, and 10% area closure) wit... by Jennie E. Rheuban (735526)

Effect of cilostazol on liver TNF-α (A), IL-6 (B), NFκβ (C) and TGFβ (D) in TAA-induced fibrosis in rats. by Sally A. El Awdan (710176)

Other bacterial species were not biotinylated by Agr-ID. Agr-ID and ATP, with or without biotin, were incubated with <i>Escherichia coli</i> (A), <i>Pseudomonas aeruginosa</i> (B),... by Lijuan Qian (3131523)

HEK293 cells were not biotinylated by Agr-ID. (A) Agr-ID and ATP, with or without biotin, were incubated with HEK293T cells for 30 min, followed by co-staining with Streptavidin-64... by Lijuan Qian (3131523)

Rumination time through 120 DIM and milk composition for the first 17 weeks of lactation of control cows and cows supplemented with <i>S</i>. <i>baicalensis</i> extract (SBE) for e... by K. E. Olagaray (6256859)

Kat60 lacking the MIT domain does not disassemble microtubules at low levels of accumulation in cells. by Kyle D. Grode (725568)

Kat60 lacking the MIT domain disassembles microtubules at high levels of accumulation in cells. by Kyle D. Grode (725568)

Inducible expression of Kat60 results in measurable microtubule disassembly in our single-cell assay. by Kyle D. Grode (725568)

Fig 5 - by Melissa A. Johnson (3847954)

Silkworm ovaries and ovarioles infected by <i>N</i>. <i>bombycis</i>. by Chunxia Wang (766713)

Macrophages inhibit the invasion of intestinal epithelial cells by <i>K</i>. <i>pneumoniae in vitro</i>. by Hitoshi Tsugawa (296864)

<b> </b> Spatial memory assessment in Morris water maze test. 5A: Effect of different treatments on time spent in the target zone. Alcl3 significantly decreased the time spent in the target zone with respect to the saline-treated group (p < 0.01). Two injections of exosomes prevented the impairment effect of Alcl3 on spatial memory compared to the Alcl3-treated group (p < 0.05). Two or five injections of exosomes in healthy rats impaired spatial memory. 5B: The swimming trajectory of each group in the probe test. No.2 was the quadrant area. Each value represents mean ± SEM, n = 6, **p < 0.01 and ***p < .001 vs. saline group and ⁺p < 0.05 vs. Alcl3 group. <i>Abbreviation</i>s: Sal, Saline; Exo [2], Two injections of exosomes; Exo [5], Five injections of exosomes. by Atefeh Sadeghi (21253051)

“…Two injections of exosomes prevented the impairment effect of Alcl3 on spatial memory compared to the Alcl3-treated group (p < 0.05). Two or five injections of exosomes in healthy rats impaired spatial memory. 5B: The swimming trajectory of each group in the probe test. …”

Comparison of the effect of no drug (0) compared with maximum (M) dose for LABE (4000 mg/ml), HDZ (1000 mg/ml), Mdopa (10,000 mg/ml) and Pravastatin (20 mg/ml) after 1 day in cultu... by Subrata Gangooly (354333)

Prenyllongnols A–D, New Prenylated Acylphloroglucinols that Fight Concanavalin A‑Induced Autoimmune Hepatitis by Zhengyi Shi (8978924)

“…Compounds <b>1</b>–<b>4</b> exhibited remarkable immunosuppressive activities in murine splenocyte proliferation under the induction of concanavalin A (Con A), and IC₅₀ values ranged from 2.98 ± 0.21 to 6.34 ± 0.72 μM. …”