Dispersal of synaptic mGluR1 clusters by Aβ requires NMDAR and VDCC activity. by Francesco Roselli (211670)

“…(A, B) Aβ downregulates surface mGluR1 (surface cluster size 66.0±2.8%, N = 10, n = 300, p<0.05); pre-treatment with either MK801 (10 µM) or verapamil (50 µM) blocked this effect (102.9±10.5%, for MK801+Aβ vs. …”

MDR1 mRNA content of K562/A02 cell line by different interferes by Baoan Chen (53879)

“…From lane 5 to lane 7 were MDR1 mRNA extracted from K562/A02 incubated with low Tet-, medium Tet- and high Tet-loaded 0.1 FeO-MNPs mdr1 mRNA was significantly decreased by over 100-fold.…”

Poly(I:C) at a low dose inhibits IL-33-induced AHR and acute eosinophilia. by Li She (2204779)

“…<p><b>A.</b> Groups of mice as indicated were treated with PBS, IL-33 with or without Poly(I:C) (5 μg/mouse) as indicated. …”

Neuroprotection and immunomodulation by dimethyl fumarate and a heterologous fibrin biopolymer after ventral root avulsion and reimplantation by Paula R. G. Kempe (10411064)

“…Results: Treatment with DMF at a dose of 15 mg/kg was found to be neuroprotective and immunomodulatory because it preserved motoneurons and synapses and decreased astrogliosis and microglial reactions, as well as downregulated the expression of pro-inflammatory gene transcripts. …”

Table_1_Suicide risk among female breast cancer survivors: A population–based study.docx by Jian Shi (141852)

“…A nomogram was constructed to predict the suicide probability for individual survivors with a C-index of 0.62 (95%CI: 0.59-0.66).…”

Image_1_Suicide risk among female breast cancer survivors: A population–based study.tif by Jian Shi (141852)

“…A nomogram was constructed to predict the suicide probability for individual survivors with a C-index of 0.62 (95%CI: 0.59-0.66).…”

Image_2_Suicide risk among female breast cancer survivors: A population–based study.tif by Jian Shi (141852)

“…A nomogram was constructed to predict the suicide probability for individual survivors with a C-index of 0.62 (95%CI: 0.59-0.66).…”

Critical temperature <em>T_c</em> for different values of the anisotropy parameter <em>a</em> for the π-flux cubic lattice model at half-filling (from top to bottom, <em>... by G Mazzucchi (557358)

“…</strong> Critical temperature <em>T_c</em> for different values of the anisotropy parameter <em>a</em> for the π-flux cubic lattice model at half-filling (from top to bottom, <em>a</em> = 0, 0.05, 0.1, 0.25, 0.5, 0.75, 1).</p> <p><strong>Abstract</strong></p> <p>We study the superfluid properties of attractively interacting fermions hopping in a family of 2D and 3D lattices in the presence of synthetic gauge fields having π-flux per plaquette. …”

Diagnostic Algorithm for Glycogenoses and Myoadenylate Deaminase Deficiency Based on Exercise Testing Parameters: A Prospective Study by Fabrice Rannou (775170)

“…The lactate/rest ratio at the 10th minute of recovery from exercise displayed the best AUC (1.0) for discriminating between Decreased and Absent MAD activities. The resulting decision tree achieved a diagnostic accuracy of 86.3%.…”

CD74 deficiency in DCs reduces tumor proliferation by activation of the immune response. by Bianca Pellegrino (20314999)

Cer1 gRNA persistence after RNAi. by Bing Sun (44691)

“…<i>gRNA(RNAi)</i> for 24 hrs caused a moderate decrease in cytoplasmic gRNA compared to control gonads, but <i>gRNA(RNAi)</i> for 48 hrs caused a much larger relative decrease. …”

Data_Sheet_1_Middle Cerebellar Peduncle Width—A Novel MRI Biomarker for FXTAS?.PDF by Annie L. Shelton (5445332)

“…<p>Fragile X-associated tremor/ataxia syndrome (FXTAS) is a severe neurodegenerative movement disorder affecting over 40% of male and 16% of female FMR1 premutation carriers over the age of 50. …”

Ca²⁺ signalling and mitochondrial physiology defects in cells lacking anxA6. by Marcin Chlystun (288876)

“…(C) ΔΨm in <i>AnxA6</i>^+/+ and <i>AnxA6</i>^−/− ear fibroblasts was measured in cells equilibrated with 50 nM TMRM under resting conditions. …”

Sensitivity of various GFP insertion constructs (<i>columns A through J</i>) to protein misfolding. by Stéphanie Cabantous (92574)

“…<p>(A) Images of <i>E. coli</i> cells on plates expressing four test fusions proteins with decreasing folding robustness at 37°C. …”

Impaired bone formation in <i>Col1a1-Krm2</i> transgenic mice. by Jochen Schulze (365258)

“…<p>(A) Toluidine blue staining of non-decalcified vertebral body sections from 6 weeks old female wildtype and <i>Col1a1-Krm2</i> transgenic littermates revealing that the normal appearance of cuboidal osteoblasts (arrows) covering trabecular bone surfaces is only observed in wildtype controls (scale bars, 50 µm). …”

Dynamic profiles of the prototypic integrated system under different conditions, and a comparison to the kinetic-based model. by Jong Min Lee (271984)

“…<p>The concentration of carbon and amount of biomass within the cellular system over a simulation time of 10 h is illustrated. The decreasing lines represent the concentration of carbon (as indicated by the left <i>y</i>-axis), which is being consumed, in the system. …”

Image2_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg by Elena Chiappini (304802)

Image1_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg by Elena Chiappini (304802)

dAβ expression alters memory only when associated with APPL partial loss-of-function. by Isabelle Bourdet (783402)

Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of Clinical Disease in a Model of Arenavirus Hemorrhagic Fever by Michelle Mendenhall (201521)

“…</p> <h3>Methodology/Principal Findings</h3><p>Here, we used a model of acute arenaviral infection in outbred guinea pigs based on challenge with an adapted strain of Pichindé virus (PICV) to further preclinical development of T-705 (Favipiravir), a promising broad-spectrum inhibitor of RNA virus infections. …”