Image_7_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_1_The Recombinant Eg.P29-Mediated miR-126a-5p Promotes the Differentiation of Mouse Naive CD4+ T Cells via DLK1-Mediated Notch1 Signal Pathway.tif by Xiancai Du (10970190)

“…One week after P29 immunization of mice, we found that miR-126a-5p was significantly increased and DLK1 expression was decreased, while Notch1 pathway activation was enhanced and Th1 response was significantly stronger. …”

Image_2_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

We measured TRECs in sorted CD4 and CD8 T cells at the time points shown, and values shown were normalized per 10 cells by Claude Sportès (50669)

“…Tick marks represent rhIL-7 injections. (A) Absolute number of circulating TRECs/mm of blood diminished during the first 7 d of rhIL-7 therapy, consistent with a decrease in naive populations during this period. …”

Observations and Mechanistic Insights on Unusual Stability of Neutral Nickel Complexes with a Sterically Crowded Metal Center by Dong-Po Song (1424416)

“…Specifically, the polyethylenes with greatly decreased molecular weights were produced by neutral nickel phenoxyiminato catalysts <b>6a</b>,<b>b</b> in comparison with values for the corresponding β-ketiminato catalysts <b>5a</b>,<b>b</b>. …”

Data_Sheet_1_Determining 5HT7R’s Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine.pdf by Lu Liu (171341)

“…<p>Electroacupuncture (EA) is widely used in clinical practice to relieve migraine pain. 5-HT₇ receptor (5-HT₇R) has been reported to play an excitatory role in neuronal systems and regulate hyperalgesic pain and neurogenic inflammation. 5-HT₇R could influence phosphorylation of protein kinase A (PKA)- or extracellular signal-regulated kinase₁_/₂ (ERK₁_/₂)-mediated signaling pathways, which mediate sensitization of nociceptive neurons via interacting with cyclic adenosine monophosphate (cAMP). …”

Reduction Pathway of End-On Terminally Coordinated Dinitrogen. IV. Geometric, Electronic, and Vibrational Structure of a W(IV) Dialkylhydrazido Complex and Its Two-Electron-Reduced... by Kay H. Horn (2684512)

“…In <b>B</b>^W, the N−N force constant decreases to 6.4 mdyn/Å, which is between the values found for the Mo/W NNH₃ and NNH₂ complexes. …”

Dimanganese and Diiron Complexes of a Binucleating Cyclam Ligand: Four-Electron, Reversible Oxidation Chemistry at High Potentials by Louise A. Berben (1443439)

“…Upon replacement of the triflate bridge with the single-atom bridge of an end-bound azide ligand in <b>5</b>, the MnMn distance decreases by 0.38 Å. All of the complexes are high-spin and colorless and were characterized by magnetic susceptibility measurements, electron paramagnetic resonance spectroscopy, and electrochemical methods. …”

Class membership evaluation for a three-category example. by Remus Oşan (25703)

“…D) Color plots indicating the distribution of probabilities throughout a region containing all data points. Each shade in the color gradation indicates an increase/decrease in probability above the chance levels (grey shade represents equal low probability for all three classes). …”

Insulin Sensitivity in Adipose and Skeletal Muscle Tissue of Dairy Cows in Response to Dietary Energy Level and 2,4-Thiazolidinedione (TZD) by Afshin Hosseini (827012)

“…Fourteen nonpregnant nonlactating cows were fed a control low-energy (CON, 1.30 Mcal/kg) diet to meet 100% of estimated nutrient requirements for 3 weeks, after which half of the cows were assigned to a higher-energy diet (OVE, 1.60 Mcal/kg) and half of the cows continued on CON for 6 weeks. …”

Preventing HIV and HSV-2 through knowledge and attitudes: A replication study of a multi-component community-based intervention in Zimbabwe by Fang Yu (156838)

“…While the original intervention targeted knowledge and attitudes as a mechanism to decrease HIV/HSV-2, the Cowan study evaluated the intervention effects on knowledge, attitudes, and prevalence of HIV or HSV-2 separately. …”

Mean trends and system losses due to Ebola virus disease (EVD) outbreak (June 2014–April 2015) for bacille Calmette–Guérin (BCG) vaccinations in a census of 379 clinics providing s... by Bradley H. Wagenaar (311527)

Mean trends and system losses due to Ebola virus disease (EVD) outbreak (June 2014–April 2015) for postnatal care within 6 weeks in a census of 379 clinics providing services in Li... by Bradley H. Wagenaar (311527)

Descriptive statistics of soil Cd concentrations (mg kg⁻¹, DW) and vegetable Cd concentration (mg kg⁻¹, FW) in the PRD area. by Huihua Zhang (633008)

Fig 2 - by Bálint Kokas (3633400)

“…The red dot shows the point where between 2011–2012 the internal-external/external ratio stabilized above 1 and the complications started to decrease.…”

Table1_The Impact of a Multifaceted Pharmacist-Led Antimicrobial Stewardship Program on Antibiotic Use: Evidence From a Quasi-Experimental Study in the Department of Vascular and I... by Jinhui Xu (575158)

“…<p>Objective: The objective of the study was to assess the impact of multifaceted clinical pharmacist-led antimicrobial stewardship (AMS) program on the rational use of antibiotics for patients who receive vascular and interventional radiology therapies.</p><p>Methods: A quasi-experimental retrospective intervention design with a comparison group was applied to the practice of antibiotic use in the department of vascular and interventional radiology in a Chinese tertiary hospital. …”

Mean (± SD) of estradiol at baseline and following 12 weeks of protein supplementation and resistance exercise by Douglas Kalman (80005)

“…Within group analysis shows a significant decrease in the WB intervention was statistically significant (-9.1 pg/ml, p = 0.033). * Indicates significant difference (p < 0.05)…”

A sequence of photographs documenting I/R-induced injury in the microcirculation of a control hamster in the baseline condition (a), within 30 min of ischemia (b), 10 min (c) and 3... by Silva Bertuglia (54760)

Sleep profiles of <i>CS</i>, <i>Dah</i>, and <i>w</i>^<i>1118</i> female and male flies. by Nathan Woodling (3932906)

Table_1_Resveratrol enhances A1 and hinders A2A adenosine receptors signaling in both HeLa and SH-SY5Y cells: Potential mechanism of its antitumoral action.docx by Sonia Muñoz-López (11369454)

“…Results revealed changes leading to turning off cAMP signaling such as decreased levels of A_2A receptors and reduced adenylyl cyclase activation, increased levels of A₁ receptors and increased adenylyl cyclase inhibition, and lower levels of PKA. …”