Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor by Olga Gorelenkova Miller (2900069)

“…CWR-J02 treatment decreased lipopolysaccharide-induced inflammatory gene transcription in the microglial cells in a parallel concentration-dependent manner, documenting the anti-inflammatory potential of CWR-J02. …”

DataSheet1_Metabolic and Lipidomic Markers Differentiate COVID-19 From Non-Hospitalized and Other Intensive Care Patients.pdf by Franziska Schmelter (11780762)

“…Specifically, very-low-density lipoprotein and intermediate-density lipoprotein particles and associated apolipoprotein B and intermediate-density lipoprotein cholesterol were significantly increased, whereas cholesterol and apolipoprotein A2 were decreased. Moreover, a similarly perturbed profile was apparent when compared with other patients with cardiogenic shock who are in the intensive care unit when looking at a 1-week time course, highlighting close links between COVID-19 and lipid metabolism. …”

Peroral exposure of PKE attenuates growth of orthotopic PC-3M-luc2 xenografts. by Emrah Yatkin (546437)

“…<p>A) PKE decreases cell proliferation index. Representative images of pH-H3-immunostainings are shown. …”

Decrement in serum total cholesterol in male and female patients in statin group (SG) and nonstatin group (NSG) during 12 months GH replacement by John P Monson (80972)

“…<p><b>Copyright information:</b></p><p>Taken from "Growth hormone (GH) replacement decreases serum total and LDL-cholesterol in hypopituitary patients on maintenance HMG CoA reductase inhibitor (statin) therapy"</p><p></p><p>Clinical Endocrinology 2007;67(4):623-628.…”

Decrement in serum LDL-cholesterol in male and female patients in statin group (SG) and nonstatin group (NSG) during 12 months GH replacement by John P Monson (80972)

“…<p><b>Copyright information:</b></p><p>Taken from "Growth hormone (GH) replacement decreases serum total and LDL-cholesterol in hypopituitary patients on maintenance HMG CoA reductase inhibitor (statin) therapy"</p><p></p><p>Clinical Endocrinology 2007;67(4):623-628.…”

Hypoxia Down-Regulates Neutrophils and Protects Lung Tissue from Inflammatory Damage by Manfred Thiel (310810)

“…<div><p>(A) Exposure of IT LPS-injected mice to hypoxic (10%) oxygen levels for 48 h atmosphere leads to a significantly decreased accumulation of PMNs (left graph), production of LPS-triggered oxygen reactive metabolites in lungs (center graph), and improved lung gas exchange (right graph) compared to a control group of endotoxin-treated mice that were kept at ambient (21%) oxygen. …”

Hierarchical Binding of AP2µ to BCR-derived Minimal YxxØ Motifs. by Kathleen Busman-Sahay (276439)

“…Peptides were also tested across a decreasing range of concentration (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054938#pone.0054938.s002" target="_blank">Figure S2</a>). …”

Modulation of cardiovascular function by rooibos in adults at risk for cardiovascular disease by Maria Diana Hartnick (7007012)

“…Objective 2: The effect of daily Rooibos consumption over 12 weeks on the cardiovascular system included the following outcomes: grade 1 diastolic dysfunction counts decreased from 63 (28%) to 47 (21.5%), grade 2 diastolic dysfunction decreased from 46 (21%) to 24 (11%) and grade 3 diastolic dysfunction decreased from 5 (2.3%) to 3 (1.4%). …”

Cluster transcriptome meta-analysis & ATP:ADP ratio. by Rainer Machné (160042)

“…Experiments were sorted into 5 clusters (column numbers) by the SOTA algorithm <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037906#pone.0037906-Herrero1" target="_blank">[104]</a> and plotted in decreasing order (from left to right) of the means of cluster A’s values. …”

Phase precession in different cortical layers. by Eric Reifenstein (588140)

“…<p>Phase-precession slope generally does not depend on the cell's cortical layer (A and C). However, phase precession is decreased in layer III, as measured by the correlation (B and D). …”

Effects of Age, Gender, BMI, and Anatomical Site on Skin Thickness in Children and Adults with Diabetes by José G. B. Derraik (147881)

“…The thicknesses of both the dermis and subcutis were assessed using ultrasound with a linear array transducer, on abdominal and thigh skin.…”

Supplementary Material for: Contribution of Extracytoplasmic Function Sigma Factors to Transition Metal Homeostasis in <i>Cupriavidus metallidurans</i> Strain CH34 by Grosse C. (4105339)

“…Concerning the two ‘(ECF)’ group proteins, <i>rpoQ</i> was strongly upregulated by Cu(II) and deletion of <i>rpoR</i> led to a small decrease in copper resistance. Of the three ECF:RpoE-encoding genes, <i>rpoP</i> was not transcribed under the conditions tested, <i>cnrH</i> was upregulated by Ni(II) and essential for nickel resistance as known before. …”

Table_3_Structurally rich dry grasslands – Potential stepping stones for bats in open farmland.docx by Sophie P. Ewert (14512787)

“…While a high biodiversity value of dry grasslands is acknowledged for plants and insects, locally and on landscape level, their relevance for mobile species, such as bats, is unknown. …”

Data_Sheet_2.xlsx by Qianqian Shi (158387)

“…<p>Meloidogyne incognita is highly specialized parasite that interacts with host plants using a range of strategies. The effectors are synthesized in the esophageal glands and secreted into plant cells through a needle-like stylet during parasitism. …”

Distinct activation of the sympathetic adreno-medullar system and hypothalamus pituitary adrenal axis following the caloric vestibular test in healthy subjects by Sebastian Cozma (4915765)

“…</p><p>Results</p><p>Following caloric vestibular test-evoked vertigo, salivary α-amylase and cortisol showed distinct trends in their production after acute stress: Student’s t-test was used to compare the α-amylase vs cortisol slopes of the respective interpolated regression lines, and the difference was significant (t = -3.283; p<0.001); an increase in salivary cortisol production corresponded with a decrease in the salivary α-amylase concentration. …”

Table4_Revealing the Mechanism of Huazhi Rougan Granule in the Treatment of Nonalcoholic Fatty Liver Through Intestinal Flora Based on 16S rRNA, Metagenomic Sequencing and Network... by Yingying Liu (360782)

“…Analysis of intestinal flora showed that HRG changed the composition of intestinal flora, which was characterized by a decrease in the Firmicutes/Bacteroidetes ratio. …”

Table_2_Impairment of Multiple Mitochondrial Energy Metabolism Pathways in the Heart of Chagas Disease Cardiomyopathy Patients.pdf by Priscila Camillo Teixeira (9910065)

“…Previous studies disclosed a selective decrease in mitochondrial ATP synthase alpha expression and creatine kinase activity in CCC myocardium as compared to IDC and IC, as well as decreased in vivo myocardial ATP production. …”

Trpm4 ion channels in pre-Bötzinger complex interneurons are essential for breathing motor pattern but not rhythm by Maria Cristina D. Picardo (6388190)

“…Patch-clamp and field recordings from the preBötC in mouse slices also showed an increase in the frequency and a decrease in the magnitude of preBötC neural bursts in the presence of Trpm4 antagonist 9-phenanthrol, whereas the Trpc3 antagonist pyrazole-3 (pyr-3) showed inconsistent effects on magnitude and no effect on frequency. …”

Image_4_Pharmacological Disruption of Phosphorylated Eukaryotic Initiation Factor-2α/Activating Transcription Factor 4/Indian Hedgehog Protects Intervertebral Disc Degeneration via... by Junping Bao (10931142)

“…On the contrary, further activating p-eIF2α aggravated the NP cell degeneration, with amplification of ATF4/Ihh and a higher level of ROS and apoptosis. Additionally, applying cyclopamine (CPE) to suppress Ihh was efficient to prevent NP cell apoptosis but did not decrease the ROS level. …”

Table_8_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.xlsx by Yujia Zhang (757462)

“…The cell morphology altered dramatically 72 h after transfection, becoming rounder, with a decrease in cell number. BCP exhibited the potential to dramatically increase PC-12 cell viability while protecting cell morphology. …”