Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…This study aimed to derive benchmark concentrations from RNaseq data (transcriptomic points-of-departure; tPOD) from a short-term exposure study with early life stages of rainbow trout (RBT; Oncorhynchus mykiss) using benzo[<i>a</i>]pyrene (B[<i>a</i>]P) as the model compound. tPODs were then calibrated with higher organizational-level responses observed during an extended 28 day exposure period. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…This study aimed to derive benchmark concentrations from RNaseq data (transcriptomic points-of-departure; tPOD) from a short-term exposure study with early life stages of rainbow trout (RBT; Oncorhynchus mykiss) using benzo[<i>a</i>]pyrene (B[<i>a</i>]P) as the model compound. tPODs were then calibrated with higher organizational-level responses observed during an extended 28 day exposure period. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…This study aimed to derive benchmark concentrations from RNaseq data (transcriptomic points-of-departure; tPOD) from a short-term exposure study with early life stages of rainbow trout (RBT; Oncorhynchus mykiss) using benzo[<i>a</i>]pyrene (B[<i>a</i>]P) as the model compound. tPODs were then calibrated with higher organizational-level responses observed during an extended 28 day exposure period. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…This study aimed to derive benchmark concentrations from RNaseq data (transcriptomic points-of-departure; tPOD) from a short-term exposure study with early life stages of rainbow trout (RBT; Oncorhynchus mykiss) using benzo[<i>a</i>]pyrene (B[<i>a</i>]P) as the model compound. tPODs were then calibrated with higher organizational-level responses observed during an extended 28 day exposure period. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…This study aimed to derive benchmark concentrations from RNaseq data (transcriptomic points-of-departure; tPOD) from a short-term exposure study with early life stages of rainbow trout (RBT; Oncorhynchus mykiss) using benzo[<i>a</i>]pyrene (B[<i>a</i>]P) as the model compound. tPODs were then calibrated with higher organizational-level responses observed during an extended 28 day exposure period. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…This study aimed to derive benchmark concentrations from RNaseq data (transcriptomic points-of-departure; tPOD) from a short-term exposure study with early life stages of rainbow trout (RBT; Oncorhynchus mykiss) using benzo[<i>a</i>]pyrene (B[<i>a</i>]P) as the model compound. tPODs were then calibrated with higher organizational-level responses observed during an extended 28 day exposure period. …”

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout by Alper James Alcaraz (20977320)

“…This study aimed to derive benchmark concentrations from RNaseq data (transcriptomic points-of-departure; tPOD) from a short-term exposure study with early life stages of rainbow trout (RBT; Oncorhynchus mykiss) using benzo[<i>a</i>]pyrene (B[<i>a</i>]P) as the model compound. tPODs were then calibrated with higher organizational-level responses observed during an extended 28 day exposure period. …”

Res prevented decrease in NO production in BAECs. by Xiao lin Peng (665046)

CcnA mutation of Loop A decreases the interaction with the 5′ UTR of P2-<i>ctrA</i> mRNA and 5′ UTR of <i>gcrA</i> mRNA. by Wanassa Beroual (5314028)

Telmisartan decreased NO production in LPS-stimulated BV2 and primary neonatal rat glial cells. by Nofar Torika (3169497)

Neurosphere-derived GFP-expressing cells were cultivated with npMSC or nnMSC conditioned media, on polyornithine-coated dishes by Sabine Wislet-Gendebien (4733)

“…Cultures with nnMSC conditioned medium are illustrated in D, E and F (n = 7, ***Student T test, P < 0.0001). …”

Decrease of mitochondrial membrane potential by silvestrol. by Takayuki Kogure (235048)

Optogenetic stimulation of CA1 astrocytes for 5- or 10-min had no significant effect on cognitive function. by Jae-Hong Kim (124622)

Cell surface expression of VLA-4 and VLA-5 were decreased after a 48 h cell-culture with TKIs while CXCR-4 expression was not affected. by Ludovic Belle (293091)

A savanna response to precipitation intensity - Fig 5 by Ryan S. Berry (3913207)

Unadjusted mean monthly admission and mortality numbers during all lockdown levels and post-COVID period. by Kimesh Loganathan Naidoo (19697486)

Motion of RhoA protein bound to the C1-GAP domain of WT or mutant RhoGAPs. by Zen Kouchi (14898435)

Exogenous IL-2 and IL-7 decrease suppression of Teff proliferation and cytokine production, but do not decrease apoptosis. by Yvonne Vercoulen (259275)

Comparison of fold changes in off-rate for gD as a function of protein length (306t vs. 285t). by Tina M. Cairns (4110190)

“…Protein length was tested in the context of both gD1 (A) and gD2 (B). Bars are colored to highlight greater than 5-fold change in rates as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006430#ppat.1006430.g007" target="_blank">Fig 7</a>. …”

A decreased expression of Rab4b increased GLUT4 localization at the plasma membrane. by Vincent Kaddai (264976)