(a) the wild type with SHV in the left panel and its neighbors in the wild type are shown (b) the S130G mutant in the right panel and its neighbors in the mutant type its neighbors... by Mohd Hassan Baig (441304)

Overexpression of U1 snRNA induces decrease of U1 spliceosome function associated with Alzheimer’s disease by Zhi Cheng (729515)

“…These findings not only helped researchers better understand the functions of U1 snRNA, but also paved the way to reveal the mechanisms of AD from a different point of view and may find a new therapeutic target for the disease.…”

The <i>Becn1</i> F121A mutation inhibits the BECN1-BCL2 interaction in vivo. by Altea Rocchi (3278457)

Subjects:

Autophagosomal sequestration of Aβ42 in brain of autophagy-hyperactive mice. by Altea Rocchi (3278457)

Subjects:

<i>Becn1</i>^F121A improves the survival rate of PDAPP AD mice. by Altea Rocchi (3278457)

Subjects:

Double deletion of Zeb1 and Zeb2 causes PB cytopenia and severe differentiation defects in HSPCs. by Jueqiong Wang (11467505)

“…Bars in panels represent mean ± SD, <i>n</i> = 5 per group; *<i>p</i> < 0.05; **<i>p</i> < 0.01; ****<i>p</i> < 0.0001, Dunnett multiple comparisons test. …”

D-4F and L-5F decrease hepatic mRNA levels of monocyte-macrophage markers. by Kristine C. McGrath (8269155)

D-4F and L-5F decrease hepatic mRNA level of genes involved in gluconeogenesis. by Kristine C. McGrath (8269155)

D-4F and L-5F decrease hepatic mRNA level of genes involved in inflammation. by Kristine C. McGrath (8269155)

D-4F and L-5F decrease hepatic mRNA levels of genes involved in lipogenesis. by Kristine C. McGrath (8269155)

Decrease in BMP2-induced Smad1/5/8 phosphorylation due to Panx3 siRNA. by Tsutomu Iwamoto (715969)

Fold change with steady state myocardial mRNA levels for components of the inflammasome. by Stephanie L. Samani (17896610)

Pairwise correlations in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

Fig 1 - by Stephanie L. Samani (17896610)

Average time-to-next-treatment (TTNT) analysis measured in days of large cell transformation (LCT) versus non-large cell transformation (NLCT) groups. by Neil K. Jairath (13237338)

“…<p>The LCT group (blue line) demonstrated significantly decreased mean TTNT compared to the NLCT group (yellow line, HR 5.868, 95% CI 0.0623–0.4661, p = 0.0013).…”

Table_1_The Co-occurrence of Chronic Hepatitis B and Fibrosis Is Associated With a Decrease in Hepatic Global DNA Methylation Levels in Patients With Non-alcoholic Fatty Liver Disease.docx by FangYuan Li (11132997)

“…The co-occurrence of CHB and liver fibrosis in NAFLD patients was associated with a decrease in global DNA methylation levels.</p>…”

No contribution of TGF-α, protein phosphatase 5 or protein kinase A to decreased levels of secreted Hsp90. by Stefan Tukaj (439533)

Spatial stability is decreased in APP/PS1 mice in both dCA1 and vCA1. by Udaysankar Chockanathan (18510288)

“…<p>(A) In dCA1, stability score was significantly decreased in APP/PS1 mice relative to C57BL/6 mice (mean ± std: C57BL/6 = -0.009 ± 0.292, APP/PS1 = -0.1845 ± 0.256, p < 10⁻⁶, two-sided Wilcoxon rank-sum test, n_C57BL/6 = 295 units from 5 recording sessions, n_APP/PS1 = 167 units from 4 recording sessions). …”

Space impression evaluated using the SDM (7-point Likert scale). by Hiroyuki Fukumoto (18197728)

FlexPepDock <i>ab-initio</i> recapitulates the native backbone structure of a glycosylated peptide and its unmodified counterpart, and correctly predicts a decrease in binding affi... by Nathaniel Bloodworth (14253329)