Image_2_Nujiangexanthone A Inhibits Hepatocellular Carcinoma Metastasis via Down Regulation of Cofilin 1.TIF by Li Zhang (8200)

“…Here, we found that CFL1 was up regulated in human HCC and significantly associated with both overall survival and disease-free survival in HCC patients. Nujiangexanthone A (NJXA), the caged xanthones, isolated from gamboge plants decreased the expression of CFL1, which also inhibited the migration, invasion and metastasis of HCC cells in vitro and in vivo. …”

Seedling phenotypes of plants expressing SAUR63:X fusion proteins. by Punita Nagpal (185838)

State of the mixture distribution in response to an ABA- sequence, shown at several time points. by Dana Barniv (837537)

“…(b) This decrease causes <b><i>π</i>₂</b> to undergo a net increase. …”

Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy by Ya-yin Tan (21448519)

“…In experiments with SV40-transformed mouse glomerular mesangial cells (MCs), PCK1 and PPARγ protein expression levels were significantly decreased in polymeric IgA1 (pIgA1)-stimulated MCs, which contrasts with the increased expression of inflammatory and fibrotic factors. …”

Global glomerulosclerosis proportions predict nephropathy progression in IgA nephropathy: a multicenter retrospective analysis with propensity score matching by Wenli Zou (1643875)

“…Additionally, the multivariate Cox regression models identified higher proteinuria, decreased eGFR, higher score of tubular atrophy/interstitial fibrosis (T), higher GS proportions as independent prognostic factors for poor kidney outcomes, and corticosteroids therapy was a protective indicator of kidney outcomes. …”

EloA promotes HEL polyploidization upon PMA stimulation through enhanced ERK1/2 activity by Lanyue Hu (10942130)

“…The phosphorylation activity of ERK1/2 decreased upon the EloA inhibition, and the polyploidization process of HEL was hindered when ERK1/2 phosphorylation was inhibited by PD0325901 or SCH772984. …”

Identification of a novel nonsense mutation in α-galactosidase A that causes Fabry disease in a Chinese family by Yushi Peng (18783276)

“…<p>Fabry disease, a lysosomal storage disease, is an uncommon X-linked recessive genetic disorder stemming from abnormalities in the alpha-galactosidase gene (<i>GLA</i>) that codes human alpha-Galactosidase A (α-Gal A). …”

M⁶A-mediated up-regulation of LncRNA LIFR-AS1 enhances the progression of pancreatic cancer via miRNA-150-5p/ VEGFA/Akt signaling by Jian-Qing Chen (8271900)

“…<p>N⁶-methyladenosine (m⁶A) modification, the most abundant internal methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. …”

Image_1_Deficiency of G9a Inhibits Cell Proliferation and Activates Autophagy via Transcriptionally Regulating c-Myc Expression in Glioblastoma.TIF by Xiao Xue Ke (9698522)

“…Besides, knockdown or inhibition of G9a led to a cell cycle arrest in G2 phase, as well as decreased the expression of CDK1, CDK2, Cyclin A2, and Cyclin B1, while it induced the activation of autophagy. …”

Reprogramming of m⁶A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia by Yan-Jie Wang (793358)

“…Here, we reported that total m⁶A level of mRNAs was decreased during hypoxia, which might be mediated by the induction of m⁶A eraser, ALKBH5. …”

Food Insecurity among Homeless Adults with Mental Illness by Milad Parpouchi (3149874)

“…Younger age, needing health care but not receiving it, poorer subjective mental health, having spent over $500 for drugs and alcohol in the past month, HIV/AIDS and having gone to a drop-in centre, community meal centre or program/food bank each increased odds of food insecurity, while less than high school completion and heart disease each decreased odds of food insecurity. …”

Data_Sheet_1_TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish.PDF by Evelien Van Schoor (8069198)

“…To investigate whether a decreased TUBA4A expression could be a driving factor in ALS pathogenesis, we assessed whether TUBA4A knockdown in zebrafish could recapitulate an ALS-like phenotype. …”

Data_Sheet_1_TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish.PDF by Evelien Van Schoor (8069198)

“…To investigate whether a decreased TUBA4A expression could be a driving factor in ALS pathogenesis, we assessed whether TUBA4A knockdown in zebrafish could recapitulate an ALS-like phenotype. …”

Effects of mutations on SAUR63 properties. by Punita Nagpal (185838)

Growth and weight deficits in <i>cycG</i>^<i>HR7</i> mutant animals. by Patrick Fischer (783820)

“…Both, loss of CycG (<i>cycG</i>^<i>HR7</i>) and ubiquitous overexpression of CycG (<i>da</i>-Gal4::UAS-<i>CycG</i>) result in a significant weight reduction. However, in the combination, the weight deficit is significantly ameliorated and not further decreased, reflecting a rescue of CycG loss. …”

Confirmatory factor analysis for the six-factor model of the VIJS. by Thuy Thi Phuong Nguyen (14059656)

Haematocrit of red cells suspended in 5 different [NaCl] at 25 and 37°C compared to that in the physiological state in which [NaCl] is 148 mM and temperature 37°C (the reference li... by Chadapust J. Sudsiri (14670602)

Image3_RETRACTED: Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts.JPEG by Yingzi He (12259307)

“…Additionally, BrdU immunostaining and western blot analysis showed that TSA or VPA treatment caused a significant decrease in the percentage of S-phase cells and induced p21^Cip1 and p27^Kip1 expression, both of which are likely to explain the decrease in the amount of newly regenerated hair cells in treated embryos. …”

Image1_RETRACTED: Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts.JPEG by Yingzi He (12259307)

“…Additionally, BrdU immunostaining and western blot analysis showed that TSA or VPA treatment caused a significant decrease in the percentage of S-phase cells and induced p21^Cip1 and p27^Kip1 expression, both of which are likely to explain the decrease in the amount of newly regenerated hair cells in treated embryos. …”

Image2_RETRACTED: Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts.JPEG by Yingzi He (12259307)

“…Additionally, BrdU immunostaining and western blot analysis showed that TSA or VPA treatment caused a significant decrease in the percentage of S-phase cells and induced p21^Cip1 and p27^Kip1 expression, both of which are likely to explain the decrease in the amount of newly regenerated hair cells in treated embryos. …”