Renal function in the treatment groups. by Jun Ding (80820)

“…Herein, we evaluated whether LCZ696 attenuates renal fibrosis by inhibiting ASK1/JNK/p38 mitogen-activated protein kinase (MAPK)-mediated apoptosis in a rat model of unilateral ureteral obstruction (UUO) and in vitro. …”

Data_Sheet_1_Dynamic Changes and Prognostic Value of Gut Microbiota-Dependent Trimethylamine-N-Oxide in Acute Ischemic Stroke.doc by Chuhong Tan (6292904)

“…Trimethylamine-N-oxide (TMAO), a gut microbiota-dependent metabolite, has been shown to be proatherogenic and prothrombotic. …”

Data_Sheet_1_Elevated Serum Inflammatory Markers in Subacute Stroke Are Associated With Clinical Outcome but Not Modified by Aerobic Fitness Training: Results of the Randomized Con... by Bernadette Kirzinger (11334015)

“…It is suggested that physical fitness training may play a role in decreasing long-term inflammatory activity and supports tissue recovery.…”

Table_1_Cerebral glucose changes after chemotherapy and their relation to long-term cognitive complaints and fatigue.docx by Gwen Schroyen (13951275)

“…</p>Experimental design<p>Using [¹⁸F]-FDG-PET/CT whole-body scans, we retrospectively quantified relative cerebral glucose metabolism before and after neoadjuvant chemotherapy in a cohort of patients treated for non-metastatic breast cancer (2009-2019). …”

DataSheet1_Metformin Combining PD-1 Inhibitor Enhanced Anti-Tumor Efficacy in STK11 Mutant Lung Cancer Through AXIN-1-Dependent Inhibition of STING Ubiquitination.PDF by Zhiguo Wang (219272)

“…</p><p>Results: Through colony formation assay, Ki67 incorporation assay, and CCK-8 assay, we found that metformin significantly enhanced the killing of H460 cells and A549 cells by T cells. In NOD-SCID xenografts, metformin in combination with PD-1 inhibitor pembrolizumab effectively decreased tumor growth and increased infiltration of CD8⁺ T cells. …”

Aerobic Exercise Inhibits Sympathetic Nerve Sprouting and Restores β-Adrenergic Receptor Balance in Rats with Myocardial Infarction by Ting Chen (15205)

“…<div><p>Background</p><p>Cardiac sympathetic nerve sprouting and the dysregulation of β-adrenergic receptor (β-AR) play a critical role in the deterioration of cardiac function after myocardial infarction (MI). …”

miR-93-5p knockdown repressed hepatocellular carcinoma progression via increasing ERBB4 and TETs-dependent DNA demethylation by Yuqiang Li (2016439)

“…TETs silence relieved the influence of miR-93-5p knockdown on cell proliferation and apoptosis. miR-93-5p knockdown decreased HCC growth in a xenograft model.</p> <p>miR-93-5p knockdown repressed the progression of HCC <i>via</i> increasing ERBB4 and TETs-dependent DNA demethylation.…”

Image_1_In ovo Feeding of L-Leucine Improves Antioxidative Capacity and Spleen Weight and Changes Amino Acid Concentrations in Broilers After Chronic Thermal Stress.JPEG by Guofeng Han (12259064)

“…Subsequent RNA-seq analysis in the spleen showed that a total of 77 significant differentially expressed genes (DEGs) were identified, including 62 upregulated DEGs and 15 downregulated DEGs. …”

Table_2_Xenobiotic Effects of Chlorine Dioxide to Escherichia coli O157:H7 on Non-host Tomato Environment Revealed by Transcriptional Network Modeling: Implications to Adaptation a... by Xiaomei Shu (6206294)

“…In contrast, more genes were further downregulated with exposure to 10 μg ClO₂ at the first hour, with the number of both upregulated and downregulated genes significantly decreasing at the second hour. A total of 810 genes were uniquely upregulated at the third hour at 10 μg ClO₂, suggesting that the potency of xenobiotic effects had led to potential adaptation. …”

Data_Sheet_1_Ca2+ Cycling Impairment in Heart Failure Is Exacerbated by Fibrosis: Insights Gained From Mechanistic Simulations.pdf by Maria T. Mora (4579738)

Table_2_Tannic acid reduced apparent protein digestibility and induced oxidative stress and inflammatory response without altering growth performance and ruminal microbiota diversi... by Zuo Wang (8502849)

“…The increments of alanine aminotransferase (ALT), triglyceride (TG), cortisol (CORT), total antioxidant capacity (T-AOC), interleukin (IL)-1β, IL-6, and serumamyloid A (SAA), and decrements of globulin (GLB), immunoglobulin G (IgG), cholinesterase (CHE), glutathione reductase (GR), creatinine (CRE), growth hormone (GH), high-density lipoprotein cholesterol (HDLC), and insulin-like growth factor 1 (IGF-1) to different extents by TA addition were observed. …”

Image_1_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.jpg by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Table_3_Xenobiotic Effects of Chlorine Dioxide to Escherichia coli O157:H7 on Non-host Tomato Environment Revealed by Transcriptional Network Modeling: Implications to Adaptation a... by Xiaomei Shu (6206294)

“…In contrast, more genes were further downregulated with exposure to 10 μg ClO₂ at the first hour, with the number of both upregulated and downregulated genes significantly decreasing at the second hour. A total of 810 genes were uniquely upregulated at the third hour at 10 μg ClO₂, suggesting that the potency of xenobiotic effects had led to potential adaptation. …”

Biochemical data and western blot data. by Jun Ding (80820)

“…Herein, we evaluated whether LCZ696 attenuates renal fibrosis by inhibiting ASK1/JNK/p38 mitogen-activated protein kinase (MAPK)-mediated apoptosis in a rat model of unilateral ureteral obstruction (UUO) and in vitro. …”

Image 1_Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation.jpg by Hongyan Xu (29047)

“…</p>Methods<p>This study uses Quercus (oak) sawdust (OS) as a control to evaluate the potential of Korshinsk peashrub (KP), Hippophae rhamnoides (seabuckthorn) pruning (HRP), and Lycium barbarum (goji) pruning (LBP) in the cultivation of L. edodes by measuring parameters such as mycelium growth, yield, protein, fat, fiber, amino acids, soluble sugars, and organic acids. …”

Table_1_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.docx by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Quantification of abnormal QRS peaks predicts response to cardiac resynchronization therapy and tracks structural remodeling by Adrian M. Suszko (6577292)

“…For each precordial lead, QRSp was defined as the total number of peaks detected on the unfiltered QRS minus those detected on a smoothed moving average template QRS. CRT response was defined as >5% increase in left ventricular ejection fraction post-CRT.…”

Data_Sheet_1_The Ameliorating Effects of Bushen Huatan Granules and Kunling Wan on Polycystic Ovary Syndrome Induced by Dehydroepiandrosterone in Rats.docx by Yang Xu (178421)

“…</p>Conclusion<p>This study demonstrated BHG or KW as a potential strategy for treatment of PCOS induced by DHEA, and suggested that the beneficial role of the two medicines were mediated by different pathway with the effect of BHG being correlated with the regulation of mitochondria, while the effect of KW being attributable to protection of endoplasmic reticulum stress.…”

Data_Sheet_2_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…These insights provide a radiological foundation for further investigations into the mechanism of the glymphatic system in TLE pathophysiology.…”

DataSheet_1_Association Between Nitric Oxide, Oxidative Stress, Eryptosis, Red Blood Cell Microparticles, and Vascular Function in Sickle Cell Anemia.docx by Elie Nader (3161037)

“…<p>Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO) bioavailability promote vasculopathy in sickle cell anemia (SCA). …”