Expression of COX-2, IL-1β, and TOLLIP after treatment with lipopolysaccharide or IL-1β as an inflammatory stimulus. by Yu Hui Won (3331458)

“…<p>(A) Validation of COX-2 by induced inflammation with LPS in fibroblasts from ALS patients (lane 1, untreated ALS patient-derived iPSCs; lane 2, 1 μg/mL LPS-treated ALS patient-derived iPSCs; lane 3, 5 μg/mL LPS-treated ALS patient-derived iPSCs; lane 4, untreated normal-derived iPSCs; lane 5, 1 μg/mL LPS-treated normal-derived iPSCs; lane 6, 5 μg/mL LPS-treated normal-derived iPSCs). …”

Class I histone deacetylase inhibitor MS-275 attenuates vasoconstriction and inflammation in angiotensin II-induced hypertension by Yuhee Ryu (3370769)

“…</p><p>Methods and results</p><p>MS-275 inhibited the activity of HDAC1, HDAC2, and HDAC3, while RGFP966 weakly inhibited that of HDAC3 in a cell-free system. MS-275 and RGFP966 treatment reduced systolic blood pressure and thickness of the aorta wall in Ang II-induced hypertensive mice. …”

FIGURE 1 from Inhibition of PRL2 Upregulates PTEN and Attenuates Tumor Growth in <i>Tp53</i>-deficient Sarcoma and Lymphoma Mouse Models by Frederick Nguele Meke (17718099)

“…<p>PRL2 expression inversely correlates with PTEN and survival in human patients with sarcoma. <b>A,</b> Scatter plot of PRL2 mRNA data showing the increased expression of PRL2 mRNA in patients with TCGA SARC with TP53 mutations. …”

Datasheet1_Breathing pattern and pulmonary gas exchange in elderly patients with and without left ventricular dysfunction—modification with exercise-based cardiac rehabilitation an... by Prisca Eser (3873718)

“…</p>Methods<p>In this large multicentre observational longitudinal study, patients aged ≥65 years with acute or chronic coronary syndromes (ACS, CCS) without cardiac surgery who participated in a study on the effectiveness of exCR in seven European countries were included. …”

Yeast essential gene screens for modulators of αSyn toxicity. by Blagovesta Popova (14546)

“…<p><b>(A)</b> Growth assays of yeast cells expressing <i>GAL1</i>-driven αSyn-GFP from two genomically integrated copies in Y7092 background, used as query strain in the <i>Tet</i>-Promoters Hughes collection (yTHC) and decreased abundance by mRNA perturbation (DAmP) collection screens, with empty vector as control. …”

Image_1_Roles of Cadherin2 in Thyroid Cancer.tif by Yun Chen (279569)

“…Background<p>The majority of drug-resistant cells in Thyroid cancer (THCA) tend to exhibit an Epithelial mesenchymal transition (EMT) phenotype, and abnormal expression of the cell adhesion molecule Cadherin2 (CDH2) is a hallmark of EMT. However, the roles of CDH2 in THCA and its underlying mechanisms are unknown.…”

Semi-knockout YAP rescue heart function from valve thickening. by Wei Yu (43094)

“…<p>(A) Gross front view of hearts from 9-month-old <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i>; <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i><i>;Yap</i>^<i>fl/+</i> and <i>Vgll4</i>^<i>fl/-</i><i>;Yap</i>^<i>fl/+</i> hearts. …”

Pitting Corrosion of Thermally Aged Duplex Stainless Steels at Different Temperature for Long Time by Yongqiang Wang (211682)

Data Sheet 1_Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianch... by Hongtao Zhang (167639)

“…This study investigated myocardial mitochondrial energy metabolism as a therapeutic mechanism of SFAS in doxorubicin-induced chronic heart failure (CHF) rats.…”

Image_3_Abnormal Shift in B Memory Cell Profile Is Associated With the Expansion of Circulating T Follicular Helper Cells via ICOS Signaling During Acute HIV-1 Infection.tif by Xiaofan Lu (2319541)

“…Twenty-five study subjects were enrolled from the Beijing PRIMO clinical cohort, a prospective cohort of HIV-1-negative men who have sex with men (MSM) for the identification of cases of acute HIV-1 infection (AHI) at Beijing Youan Hospital, Capital Medical University. …”

Binding and entry of TP4 peptides in <i>E</i>. <i>coli</i>. by Shih-Han Wang (430693)

“…<p>(A) TP4 and FITC-TP4 peptides exerted similar bactericidal ability against <i>E</i>. …”

Image_6_Phenotypic changes of γδ T cells in Plasmodium falciparum placental malaria and pregnancy outcomes in women at delivery in Cameroon.jpeg by Chris Marco Mbianda Nana (14492776)

“…This study sought to investigate the involvement of γδ T cells and its subsets in placental Plasmodium falciparum malaria.</p>Methods<p>In a case-control study conducted in Yaoundé, Cameroon from March 2022 to May 2023, peripheral, placental and cord blood samples were collected from 50 women at delivery (29 PM negative: PM- and 21 PM positive: PM+; as diagnosed by light microscopy). …”

Image2_The correlation between Diabetes and age-related degeneration and the static and dynamic 3D mechanical distribution of different plantar regions.jpeg by Xiong-gang Yang (6085205)

“…</p>Materials and methods<p>A total of 20 HY adults, 16 HO adults and 15 diabetic patients were included. …”

Table3_The correlation between Diabetes and age-related degeneration and the static and dynamic 3D mechanical distribution of different plantar regions.docx by Xiong-gang Yang (6085205)

“…</p>Materials and methods<p>A total of 20 HY adults, 16 HO adults and 15 diabetic patients were included. …”

Radio-protective efficacy of <i>Gymnema sylvestre</i> on <i>Pangasius sutchi against</i> gamma (⁶⁰Co) irradiation by Pamela Sinha (11613846)

“…<p>Freshwater fish <i>Pangasius sutchi</i> was used in this study as a vertebrate model. We evaluated the induction of certain antioxidant enzymes in various vital organs. …”

Image_14_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif by Ming Liu (105953)

“…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …”

DataSheet_1_Antigenic Cross-Reactivity Between SARS-CoV-2 S1-RBD and Its Receptor ACE2.docx by Yen-Chung Lai (6480704)

“…In this study, we confirmed the increase in antibodies against ACE2 in patients with COVID-19 and found a positive correlation between the amounts of antibodies against ACE2 and S1-RBD. …”

DataSheet_1_Sex-specific differences in immunogenomic features of response to immune checkpoint blockade.pdf by Susan C. Scott (13191618)

DataSheet_1_Kynurenic Acid and Its Analogue SZR-72 Ameliorate the Severity of Experimental Acute Necrotizing Pancreatitis.pdf by Zsolt Balla (457272)

DataSheet1_Variations in the Consumption of Antimicrobial Medicines in the European Region, 2014–2018: Findings and Implications from ESAC-Net and WHO Europe.docx by Jane Robertson (352569)

“…ESAC-Net countries consumed more penicillins (J01C; 8.7 versus 6.3 DDD per 1000 inhabitants per day), more tetracyclines (J01A; 2.2 versus 1.2), less cephalosporins (J01D; 2.3 versus 3.8) and less quinolones (J01M; 1.7 versus 3.4) than WHO Europe AMC Network countries. …”