Time of Initiating Enzyme Replacement Therapy Affects Immune Abnormalities and Disease Severity in Patients with Gaucher Disease by Renuka Pudi Limgala (3394790)

“…Skewing of CD4 and CD8 T cell numbers resulting in lower CD4/CD8 ratio and an increase in overall T cell activation were observed. A decrease in the overall B cells and an increase in NK and NKT cells were noted in the GD patients compared to controls. …”

Structural Changes, Volatile Compounds and Antioxidant Activities of Maillard Reaction Products Derived from Scallop (<i>Patinopecten yessoensis</i>) Female Gonad Hydrolysates by Jia-Run Han (6531362)

“…<p>In order to improve the utilization of scallop byproducts, scallop female gonad hydrolysates (SFGHs) were prepared using alcalase and ribose at a mass ratio of 1:2 and pH 7.0 (95°C, up to 12 h) to develop heterogeneous Maillard-type antioxidant and flavor compounds. …”

Table2_Establishment of an assistive diagnostic model for schizophrenia with oxidative stress biomarkers.xlsx by Shuying Wang (150543)

“…</p><p>Results: In SCZ patients, the blood serum levels of glucose, total (TBIL), indirect bilirubin (IBIL) and homocysteine (HCY) were significantly higher than those in HCs (p < 0.05), and the serum levels of SOD were significantly lower than those in HCs (p < 0.05). There was a negative correlation between SOD with the general symptom scores and total scores of PANSS. …”

Image_4_Metabolomics and Lipidomics Reveal the Effect of Hepatic Vps33b Deficiency on Bile Acids and Lipids Metabolism.TIFF by Kaili Fu (6497597)

“…In addition, lipid profiles were significantly altered with the lack of Vps33b in the liver. A variety of lipids, such as triglycerides and sphingomyelins, were significantly decreased in the liver and increased in the serum of hepatic Vps33b-depleted mice compared to those in wild-type mice. …”

Arp2 Hydrolyzes ATP Rapidly upon Filament Nucleation by Mark J Dayel (70485)

“…<div><p>(A) Arp2/3 (2 μM) was covalently crosslinked to γ-³²P-AzidoATP by exposure to UV light. …”

Data_Sheet_1_Effects of Salinity on the Biodegradation of Polycyclic Aromatic Hydrocarbons in Oilfield Soils Emphasizing Degradation Genes and Soil Enzymes.docx by Yang Li (7082)

“…In order to explain the responses of soils and bacterial communities, analysis was conducted including soil properties, structures of bacterial community, PAH degradation genes and soil enzyme activities during a biodegradation process of PAHs in oilfield soils. …”

Image_5_Integrated Isoform Sequencing and Dynamic Transcriptome Analysis Reveals Diverse Transcripts Responsible for Low Temperature Stress at Anther Meiosis Stage in Rice.TIF by Zhaojun Qu (9012878)

“…We performed RNA-seq and ISO-seq experiments to study the genome-wide transcript expression profiles in low-temperature anthers. A total of 4,859 differentially expressed transcripts were detected between the low-temperature and control groups. …”

Data_Sheet_1_Inhibition of SARS-CoV-2 3CL Mpro by Natural and Synthetic Inhibitors: Potential Implication for Vaccine Production Against COVID-19.PDF by Anwar Ullah (765339)

“…<p>COVID-19 has created a pandemic situation all over the world. It has spread in nearly every continent. …”

Image_3_Integrated single-cell transcriptome analysis of the tumor ecosystems underlying cervical cancer metastasis.jpeg by Chunbo Li (167815)

“…By comparing the differently expressed gene of macrophages between tumor and metastatic LN, we discovered that C1QA+ MRC1^low macrophages were enriched in a tumor, whereas C1QA+ MRC1^high macrophages were enriched in metastatic LN. …”

Table_2_Association of Increased Circulating Acetic Acid With Poor Survival in Pseudomonas aeruginosa Ventilator-Associated Pneumonia Patients.docx by Xiaoling Qi (5564066)

“…</p>Results<p>We developed a partial least squares discriminant analysis (PLS-DA) model to examine differential SCFAs in 49 patients with PA-VAP. …”

Breakup-Free and Colorful Liquid Metal Thin Films via Electrochemical Oxidation by Yi Chen (38576)

“…Moreover, the phase change nature of liquid metal provides an opportunity to create conformal electronics in a substrate-free manner. However, thin liquid metal films tend to break during the solid-to-liquid transition due to the high surface tension of liquid metal. …”

Image_1_Integrated Isoform Sequencing and Dynamic Transcriptome Analysis Reveals Diverse Transcripts Responsible for Low Temperature Stress at Anther Meiosis Stage in Rice.PDF by Zhaojun Qu (9012878)

“…We performed RNA-seq and ISO-seq experiments to study the genome-wide transcript expression profiles in low-temperature anthers. A total of 4,859 differentially expressed transcripts were detected between the low-temperature and control groups. …”

Table_1_Serum HBsAg and HBcrAg is associated with inflammation in HBeAg-positive chronic hepatitis B patients.docx by Jing Zhao (21160)

“…Inflammation regression was defined as a ≥1-grade decrease according to the Scheuer scoring system.…”

DataSheet_1_Downregulation of Brassica napus MYB69 (BnMYB69) increases biomass growth and disease susceptibility via remodeling phytohormone, chlorophyll, shikimate and lignin leve... by Na Lin (69470)

“…<p>MYB transcription factors are major actors regulating plant development and adaptability. Brassica napus is a staple oil crop and is hampered by lodging and diseases. …”

Image_8_Integrated Isoform Sequencing and Dynamic Transcriptome Analysis Reveals Diverse Transcripts Responsible for Low Temperature Stress at Anther Meiosis Stage in Rice.tif by Zhaojun Qu (9012878)

“…We performed RNA-seq and ISO-seq experiments to study the genome-wide transcript expression profiles in low-temperature anthers. A total of 4,859 differentially expressed transcripts were detected between the low-temperature and control groups. …”

Video_1_Inhibition of SARS-CoV-2 3CL Mpro by Natural and Synthetic Inhibitors: Potential Implication for Vaccine Production Against COVID-19.MP4 by Anwar Ullah (765339)

“…<p>COVID-19 has created a pandemic situation all over the world. It has spread in nearly every continent. …”

Quantum-Chemical Investigation of the Conformational Dynamics of Mono-<i>meso</i>-phenyl-Substituted Octaalkylporphyrins in the Triplet Excited State by Igor V. Avilov (2713900)

“…The calculated T₁ → T<i>_n</i> transient absorption spectra for planar and nonplanar conformations have been compared with the corresponding experimental data obtained for the investigated compounds. A remarkable accord between experimental results and theoretical calculations on T₁ → T<i>_n</i> absorption spectra in the red and near-IR region provides additional support for the conformational reorganization leading to the formation of the highly nonplanar distortion of OEP-<i>meso</i>Ph molecule in the triplet excited state.…”

S1 Raw data - by Yongle Du (3992198)

“…By integrating metabonomics with network pharmacology, we identified core targets of ZJP against myopia and constructed a compound-gene-disease-metabolite network. The expressions of LPCAT1 and CHRNA7 were found to decrease in the LIM group but increase with ZJP treatment, whereas NOS2 expression showed the opposite pattern.…”

Image_4_Integrated single-cell transcriptome analysis of the tumor ecosystems underlying cervical cancer metastasis.jpeg by Chunbo Li (167815)

“…By comparing the differently expressed gene of macrophages between tumor and metastatic LN, we discovered that C1QA+ MRC1^low macrophages were enriched in a tumor, whereas C1QA+ MRC1^high macrophages were enriched in metastatic LN. …”

Data_Sheet_1_Molecular Dynamic Simulation of the Porcine Pancreatic Lipase in Non-aqueous Organic Solvents.pdf by Zi-Shi Chen (9116690)

“…The results showed that the backbone and active pocket RMSD, and hydrophilic ASA of PPL in three solvents increase with the increase in the solvent LogP, while the Rg, hydrophobic ASA, and H-bond between the solvent and PPL decrease. Among the three organic solvents, DMSO acts as a better solvent, in which the PPL can be loose and extended, and retains its native backbone in DMSO compared to PRG and EtOH. …”