Image_2_Metabolomics and Lipidomics Reveal the Effect of Hepatic Vps33b Deficiency on Bile Acids and Lipids Metabolism.TIF by Kaili Fu (6497597)

“…In addition, lipid profiles were significantly altered with the lack of Vps33b in the liver. A variety of lipids, such as triglycerides and sphingomyelins, were significantly decreased in the liver and increased in the serum of hepatic Vps33b-depleted mice compared to those in wild-type mice. …”

Image_6_Integrated single-cell transcriptome analysis of the tumor ecosystems underlying cervical cancer metastasis.jpeg by Chunbo Li (167815)

“…By comparing the differently expressed gene of macrophages between tumor and metastatic LN, we discovered that C1QA+ MRC1^low macrophages were enriched in a tumor, whereas C1QA+ MRC1^high macrophages were enriched in metastatic LN. …”

11β-hydroxysteroid dehydrogenase type-II activity is affected by grapefruit juice and intense muscular work by Christopher Kargl (6150389)

“…Results GFJ treatment decreased baseline 11β-HSD2 enzyme activity (44%) and Sal-E (28%) compared to CON (both, p < 0.05). …”

Image_3_Inulin accelerates weight loss in obese mice by regulating gut microbiota and serum metabolites.tif by Zeang Wu (13872479)

“…Sixteen high-fat diets (HFDs)-induced obese C57BL/6 mice were converted to a normal diet and then randomized into two groups, OND (obese mice + normal diet) group gavage-fed for 10 weeks with normal saline and ONDI (obese mice + normal diet + inulin) group with inulin at 10 g/kg/day. …”

Spry1 and Spry4 differently regulate Akt activation, hAoSMC differentiation and proliferation. by Xuehui Yang (225729)

“…<p>A) Representative immunoblot shows that overexpression of Spry1 increases VSMC marker CNN1, ACTA2 and SM22α expression, whereas overexpression of Spry4 decreases expression of these markers. …”

Rats with Chronic, Stable Pulmonary Hypertension Tolerate Low Dose Sevoflurane Inhalation as Well as Normal Rats Do by Xiaoqing Yin (2657140)

“…The values of Ea, R/L ratio, ESP, SW, PRSW, +dP/dt_max and the slope of the dP/dtmax-EDV relationship increased significantly in PAH rats (<i>P</i><0.05). Sevoflurane induced a concentration-dependent decrease of systemic and pulmonary blood pressure, HR, RV contractility, and increased the R/L ratio in both groups. …”

Data_Sheet_1_Canopy light distribution effects on light use efficiency in wheat and its mechanism.docx by Jie Zhang (64655)

“…An increase in row spacing positively affects CLD. A decrease (16.64%) of PAR interception in the upper layer, an increase (19.76%) in the middle layer, improved PUE (12.08%), and increased yield (9.38%) were recorded. …”

Image_10_Integrated single-cell transcriptome analysis of the tumor ecosystems underlying cervical cancer metastasis.jpeg by Chunbo Li (167815)

“…By comparing the differently expressed gene of macrophages between tumor and metastatic LN, we discovered that C1QA+ MRC1^low macrophages were enriched in a tumor, whereas C1QA+ MRC1^high macrophages were enriched in metastatic LN. …”

Female protection against diabetic kidney disease is regulated by kidney-specific AMPK activity by Hak Joo Lee (18423230)

“…RNA-seq and metabolomic analysis identified a decrease in the degradation pathway of phenylalanine and tyrosine resulting in increased urinary phenylalanine and tyrosine levels in females. …”

S1 File - by Li Zeng (77324)

“…IM was well tolerated, although it was associated with a significant change in cognitive function (<i>P</i> < 0.001), fatigue (<i>P</i> = 0.015), pain (<i>P</i> = 0.015), nausea/vomiting (<i>P</i> = 0.029), insomnia (<i>P</i> = 0.019), diarrhea (<i>P</i> = 0.003) and financial difficulties (<i>P</i> < 0.001). …”

Identification of Metabolic Pathways in <i>Daphnia magna</i> Explaining Hormetic Effects of Selective Serotonin Reuptake Inhibitors and 4‑Nonylphenol Using Transcriptomic and Pheno... by Bruno Campos (1922251)

“…These changes in functional and metabolic pathways are consistent with previously reported SSRIs and 4-nonylphenol hormetic effects in <i>D. magna</i>, including a decrease in reserve carbohydrates and an increase in respiratory metabolism.…”

Image_1_Enhanced lipid metabolism confers the immunosuppressive tumor microenvironment in CD5-positive non-MYC/BCL2 double expressor lymphoma.tiff by Meng-Ke Liu (10306315)

“…Meanwhile, CD36 expression was upregulated and strongly correlated to the proportion of M2 macrophages in CD5+ non-DE DLBCL. In vitro, a DLBCL cell line (LY10) overexpressing CD5 significantly increased M2 proportion in comparison with control when cocultured with peripheral blood mononuclear cells (PBMCs). …”

Table_1_Cooperation of arbuscular mycorrhizal fungi and bacteria to facilitate the host plant growth dependent on soil pH.DOCX by Zengwei Feng (6583163)

“…We demonstrate that microbes cooperate to facilitate host plants to grow well in their native soils with the original pH. Meanwhile, a high-throughput sequencing-guided pipeline to efficiently screen for beneficial microbes is established.…”

Table_2_Seasonal differences in intestinal flora are related to rats’ intestinal water metabolism.xlsx by Jing Li (10611)

“…The high temperature and humidity season could lead to an increase in intestinal water metabolism and intestinal water content in rats, whereas the low temperature and humidity season could lead to a decrease, which was closely related to the change in microflora. …”

Table_2_Transcriptional profile reveals the physiological responses to prey availability in the mixotrophic chrysophyte Poterioochromonas malhamensis.XLSX by Mingyang Ma (9188650)

“…In their natural ecosystems, mixotrophic flagellates may encounter microalgal prey of different digestibility, which may affect the carbon flow. To date, a molecular biological view of the metabolic processes in the mixotrophic flagellate Poterioochromonas malhamensis during nutritional adaptation and feeding on microalgal prey of different digestibility is still lacking. …”

Table 2_The role and mechanism of “eight famous herbals in Zhejiang” in cancer via network pharmacology and experimental validation.docx by Ziheng Ni (19739053)

“…Finally, we found that three active ingredients (ferulic acid, luteolin, and quercetin) could inhibit the proliferation of NSCLC cells and decrease the protein expression of EGFR in a concentration-dependent manner. …”

Interaction of land management and araucaria trees in the maintenance of landscape diversity in the highlands of southern Brazil by Rafael Barbizan Sühs (6000284)

“…<div><p>In the southern Brazilian highlands, pre-Columbian societies created domesticated landscapes through the use and management of forests, including nurse <i>Araucaria angustifolia</i> trees, a common conifer in these regions. Nowadays, local smallholders still use traditional practices, such as burning, to promote vegetation for cattle grazing in highland grasslands. …”

Image_1_Integrated single-cell transcriptome analysis of the tumor ecosystems underlying cervical cancer metastasis.jpeg by Chunbo Li (167815)

“…By comparing the differently expressed gene of macrophages between tumor and metastatic LN, we discovered that C1QA+ MRC1^low macrophages were enriched in a tumor, whereas C1QA+ MRC1^high macrophages were enriched in metastatic LN. …”

Table 1_Dietary phosphorus restriction induced phospholipid deficiency, endoplasmic reticulum stress, inflammatory response and gut microbiota disorders in Lateolabrax maculatus.do... by Zixiang Wu (312334)

“…In contrast to fish fed the NP diet, fish fed the LP diet exhibited a decrease in the abundance of potential metabolically promoted probiotics (e.g., Lactococcus lactis) and an increase in the abundance of potential pathogenic bacteria (e.g., Plesiomonas) in the gut. …”

Table_2_Dose of Alcohol From Beer Required for Acute Reduction in Arterial Stiffness.DOCX by Masato Nishiwaki (666290)

“…However, B50, B100, and B200 caused a significant decrease in arterial stiffness for approximately 30–60 min: heart-brachial pulse wave velocity (B50: −4.5 ± 2.4%; B100: −3.4 ± 1.3%; B200: −8.1 ± 2.6%); brachial-ankle pulse wave velocity (B50: −0.6 ± 2.0%; B100: −3.3 ± 1.1%; B200: −9.3 ± 3.0%); heart-ankle pulse wave velocity (B50: −3.7 ± 0.3%; B100: −3.3 ± 0.9%; B200: −8.1 ± 2.7%); and cardio-ankle vascular index (B50: −4.6 ± 1.3%; B100: −5.6 ± 0.8%; B200: −10.3 ± 3.1%). …”