Standardized cumulative sum of effective gene conversion rate and G+C content. by Marie Touchon (118515)

“…A decrease in the cumulative sum reflects regions of lower-than-expected values of the statistics. …”

Proof of principle that the endothelial surface layer detected by AFM is the eGC. by Anne Wiesinger (487509)

“…The heparinase-induced loss of filaments and thinning of the aortic eGC observed by EM (A, B) corresponded well with the decrease in eGC thickness detected by AFM (C, D). Each dot refers to a different tip position showing an average value of ≥5 force indentation curves. …”

<i>In vitro</i> methylation with SssI methylase abrogates <i>PDHA2</i> promoter constructs activity. by Ana Pinheiro (160498)

“…<p>Constructs, either methylated or mock-methylated, were transiently transfected into SH-SY5Y cell line. Transfections were carried out using 0.5 µg of the <i>PDHA2</i> reporter constructs or the empty pGL2 vector. …”

Weight loss and bacterial dissemination increases over time during invasive infection. by Sinead M. Hurley (3132807)

“…<i>pyogenes</i> AP1 were weighed before infection and at 5, 12, and 18 hours post infection and the decrease in body weight was calculated (A). …”

Targeted GRP silencing inhibited neuroblastoma progression. by Pritha Paul (382332)

“…<p>(A, D) BE (2)-C/Tet/shGRP (+DOX) cells and SH-SY5Y/Tet/shGRP (+DOX) cells, respectively, demonstrated a decrease in soft agar colony formation in comparison to Tet/shGRP (-DOX) cells or Tet/shCON (+DOX) cells. …”

Average biofilm coverage as a function of distance from the coverslip for <i>R. palustris</i> biofilms grown under (A) heterotrophic and (B) photoheterotrophic conditions. by Chase Kernan (757181)

“…<p>Each curve is labeled by the time since inoculation and represents an average of multiple scans within each sample obtained by interpolation and binning of values at similar depths. The mean standard deviation for coverage values binned at the same depth was 2.5%. …”

Implications of SARM1 Inhibitor Failed to Protect HD Dorsal Root Ganglion (DRG) Axon Induced Damage from Laser by Abigail Wei (22494863)

“…For axons that experienced segmentation, SARM1 increased the distance from the damage point for HD cells, while it helped decrease the distance for WT cells. …”

Modulation of HCN and calcium currents by extracellular pH. by Saju Balakrishnan (58265)

“…The currents were evoked by voltage steps to -110 and -40 mV, respectively, from a holding potential of -70 mV (close to resting potential measured in CA1 neurons). …”

Comparison of Bursting Activity in Real and Modelled Oxytocin Cells. by Enrico Rossoni (271791)

“…<p>(A) A typical burst in a model cell plotted as instantaneous firing rate (each point is the reciprocal of the interval since the previous spike). …”

Functional Genetic Variants in <em>DC-SIGNR</em> Are Associated with Mother-to-Child Transmission of HIV-1 by Geneviève Boily-Larouche (152000)

“…In homozygous H1 infants bearing both the p-198A and int2-180A mutations, we observed a 4-fold decrease in the level of placental DC-SIGNR transcripts, disproportionately affecting the expression of membrane-bound isoforms compared to infant noncarriers (P = 0.011).…”

Supplementary Material for: Impact of shelf-life extension on platelet availability: Results from an inventory management modelling study by Brixner V. (17981086)

“…Results: Over 2.2 years, a total of 74,322 PC units were produced and 62,178 units were released at the Frankfurt Institute; the overall overproduction rate was 19.5%. Shortage rates decreased with an increase in PC shelf-life and/or increase in overproduction rates. …”

Video1_Re-expansion of vertebral compression fractures in patients with multiple myeloma with percutaneous vertebroplasty using spinejack implants: a preliminary and retrospective... by Claudio Pusceddu (15831989)

“…In the 6-month follow-up, the mean VAS score decreased from 5.4 ± 1.0 to 0.2 ± 0.5 with a mean reduction of 96.3%. …”

Effect of acute infection with <i>P. chabaudi</i> on myeloid progenitor cells in the bone marrow. by Nikolai N. Belyaev (419166)

“…Data are from two experiments with 4–5 BM samples per experiment and shown as mean ± SEM of total number of CFU-GM per femur (*: <i>P</i>≤0.05, two-tailed Student's <i>t</i>-test). …”

Right Ventricular Dyssynchrony Before and After Pulmonary Thromboendarterectomy in Patients with Chronic Thromboembolic Pulmonary Hypertension by Darrin J. Wong (4230487)

“…</p> <p><b>Results:</b> Mean RV free wall strain did not change significantly after PTE (−11.4 ± 5.7 to −11.2 ± 5.6%, <i>p</i> = 0.67). …”

Aspirin treatment inhibits osteoclast activities. by Takayoshi Yamaza (67506)

“…The graph represents mean±SD (n = 5; [<i>P</i><0.01 vs. Sham; #<i>P</i><0.05 vs. …”

Influence of treatment with MG132 and GM6001 after infection. by Ping-Sung Chiu (386303)

“…(F) Ratios of claudin-5 were decreased significantly (*<i>P</i><0.05) in GM6001-treated mice versus infected mice. …”

Comparative genome hybridization of four spontaneous ceftazidime-resistant mutants revealing mutations in gene PA3047. by Bartolomé Moya (265834)

“…In mutant 1A1 and 1D4, a slight decrease in signal (+) pointed towards a small genetic change, e.g., a single point mutation.…”

Dysfunction of Nrf-2 in CF Epithelia Leads to Excess Intracellular H₂O₂ and Inflammatory Cytokine Production by Junnan Chen (270183)

“…Proteomic analysis of three in vitro and two in vivo models revealed a decrease in antioxidant proteins that regulate H₂O₂ processing, by ≥2 fold in CF vs. matched normal controls. …”

Nerve conduction and excitability variables before, during and after ischemia. by Jeannette Hofmeijer (424416)

“…<p>Variables before induction of ischemia are presented as mean values ± standard deviation. Values during and after ischemia are expressed as a percentage of values before ischemia with negative values indicating a decrease and positive values an increase. …”

Additional file 7: of Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy by Nora Huang (3661855)

“…Twelve- to 16-week-old male Nlrp3 KO and WT mice were subjected to CLP or sham surgery. qRT-PCR analysis of myosin heavy chain (Myh) 2, Myh4, and Myh7 expression in tibialis anterior (TA) muscles of sham (n = 5) and CLP (n = 5) mice at 96 h after surgery as indicated (WT sham: n = 5; WT CLP: n = 9; Nlrp3 KO sham n = 5; Nlrp3 KO: CLP n = 6). mRNA expression was normalized to Gapdh. …”