Generation of transcriptome datasets. by Paul Montague (285622)

“…The resultant transcriptome database (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0009892#pntd.0009892.s007" target="_blank">S2 Table</a>) set out for each pairing in order of decreasing p values and corresponding fold changes.…”

The hypothalamic-pituitary-thyroid axis in TRH deficient mice. by Yasuyo Nakajima (316579)

“…E) Reflecting hypothyroidism induced by thyroidectomy (TX), the serum TSH level in the wild-type mice showed an approximately 25-fold increase (Wt+TX, n = 6), but TRHKO mice (TRH−/−) showed only about a 6-fold increase (TRH−/−+TX, n = 6). **, <i>p</i><0.01. …”

Comparison of methods to monitor for myelopathic progression in DCM. by Allan R. Martin (3772705)

“…<p>Top panel: The bar graph displays the fraction of subjects that are deemed to be stable (green), borderline declined (yellow), or declined (red) for each clinical and MRI method of monitoring. For mJOA, a 1-point decrease is considered borderline and ≥ 2-point decreases are considered declined. …”

HuR potently and persistently represses IGF-IR IRES-mediated translation initiation by Zheng Meng (9293)

“…Note that a two log decrease in efficiency of IRES-mediated translation in the presence of HuR is maintained throughout the course of the experiment.…”

Mibefradil induces transient alleviation of heat and mechanical sensitivity in non-diabetic rats. by Aleksandar Lj. Obradovic (547423)

“…<p>Mibefradil at 9/kg but not at 3 mg/kg causes significant, although transient, decrease in heat (***, p<0.001 at 1 hr compared to vehicle in both left and right paws; Panel A, right paw; B, left paw) and mechanical sensitivity (***, p<0.001 at 1 hr compared to vehicle in both paws; Panel C, right paw; D, left paw) in control (SAL)-rats (n = 3–9 rats per data point).…”

Degradation of cryogels. by Johanna Roether (6102689)

“…<p>Decrease in Young’s modulus over storage time(A), Changes in MSD plots after 1 day (B) and after 120 days (C) and corresponding LSM images of pure HA gels stained with Rhodamine B after 1 day (D) and 90 days (E). …”

S2 Fig - by Thomas Notermans (9767082)

“…All perturbations of the model parameters predict a decrease in tissue production in the tendon core at week 1.…”

Pairwise distance analysis. by Eun-Young Kim (16515)

“…<p>Removal of the guanosine from the APOBEC3 trinucleotide context of the edited sites produced a significant decrease in the observed pairwise genetic distances of the sequences compared to the early time point consensus sequence, expressed as number of substitutions per site (<i>P</i>-values<0.05 are considered statistically significant).…”

H&E staining and cellularity results of LF. by Jeffrey P. Brown (320020)

“…Cellularity of the LF shows a significant decrease at P14, and appeared to be lowest at P2-yrs. …”

The effect of <i>NCCRP1</i> silencing on cell proliferation in HeLa cells as analyzed by ImageJ. by Heini Kallio (197547)

“…The silencing of <i>NCCRP1</i> caused a statistically significant decrease in cell proliferation at every time point. …”

Endocannabinoid (eCB) levels in EC, DG and the CA1 region as normalized against ß-actin immunosignals. by Sonja Kallendrusch (109796)

“…In CA1, AEA did not differ from CTR after PPT. PEA showed a significant decrease 48hpl. OEA decreased at 12 and 48hpl. …”

Relationship between chromosome 9 genetic changes and immune cell abundance estimates in TCGA melanoma. by Nathan O. Siemers (216820)

“…<p>Chromosomal location is displayed on the horizontal axis, and effect size is displayed on the vertical axis. Each data point represents the results for a given locus, with significance (negative log(10) P value) indicated by the size of the data point. …”

Industrial Systems Biology of <i>Saccharomyces cerevisiae</i> Enables Novel Succinic Acid Cell Factory by José Manuel Otero (275619)

“…The resulting strain represents a 30-fold improvement in succinate titer, and a 43-fold improvement in succinate yield on biomass, with only a 2.8-fold decrease in the specific growth rate compared to the reference strain. …”

Alanine-scanning mutagenesis of EnvZ. by Emily J. Capra (236597)

“…Each value was expressed as a percentage of the decrease measured for wild-type EnvZ. …”

Theory of FRET “Spectroscopic Ruler” for Short Distances: Application to Polyproline by Ekaterina Sobakinskaya (4714518)

“…The interpretations of FRET experiments with standard Förster theory relies on the following approximations: (i) a point-dipole approximation (PDA) for the coupling between transition densities of the chromophores, (ii) a screening of this coupling by the inverse optical dielectric constant of the medium, and (iii) the assumption of fast isotropic sampling over the mutual orientations of the chromophores. …”

Theory of FRET “Spectroscopic Ruler” for Short Distances: Application to Polyproline by Ekaterina Sobakinskaya (4714518)

“…The interpretations of FRET experiments with standard Förster theory relies on the following approximations: (i) a point-dipole approximation (PDA) for the coupling between transition densities of the chromophores, (ii) a screening of this coupling by the inverse optical dielectric constant of the medium, and (iii) the assumption of fast isotropic sampling over the mutual orientations of the chromophores. …”

Alterations of mRNA expression of podocyte and tubular markers during progression of CKD in RenTg mice. by Anne-Cecile Huby (291994)

“…Values are presented as fold increased or decreased as compared to the age matched WT mice and are mean±SEM; n = 8 and 9 for wild type and RenTg mice, respectively for each time point; *P<0,05 or **P<0,01 vs WT.…”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”