Ara-C-induced Mcl-1 degradation and cell death are inhibited upon TPA-induced ERK activation in BL41-3 cells. by Shanna K. Nifoussi (128297)

“…A representative experiment is included (upper photograph) along with the average (± SE) of 5 independent experiments. Also shown for comparative purposes is the percentage of cells exhibiting morphological apoptosis, assayed with a concentration of 1 nM TPA applied 1 hour before the addition of Ara-C (mean of 3 independent experiments ± SE run in parallel with previous studies; some of the BL41-3 cell samples not treated with TPA were included in a previous publication comparing these to BL41 parental cells (Fig. 4 in reference <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047060#pone.0047060-Vrana2" target="_blank">[23]</a>). …”

Metformin reduces lipid stores and causes intestinal fluid imbalance. by Cathy Slack (251729)

“…(<b>B</b>) Metformin treatment of female flies does not affect the number of fecal deposits produced per fly over a 24 hour period (<i>P>0.05</i>, Wilcoxen test, n = 5 (5 flies per replicate)). (<b>C</b>) Metformin treatment of female flies does not affect the size of fecal deposits as measured by the mean area of deposits (<i>P>0.05</i>, Wilcoxen test, n = 5 (5 flies per replicate)). …”

Knife, carver, jackknife: an analysis of the femicide law in Brazil by Carlos Barreto Campello Roichman (10354756)

“…The results point to an immediate decrease in the number of femicides, with a subsequent resumption of growth, indicating that there was no significant impact on these indexes. …”

Summary of the Effect of Perturbation Reported by Experimental and Simulated Methods. by Derek Ruths (42574)

“…<p>The up arrow (↑) indicates that the perturbation caused a rise in the level of the phosphorylated protein; the straight line (−) indicates no change; and the down arrow (↓) indicates that a decrease occurred. …”

Deletion of Gpr177 in embryonic epidermis leads to ablation of Wnt/β-catenin signaling in dermis. by Xiao-Jing Zhu (645748)

“…<p>(A) Quantitative RT-PCR shows a decrease in the expression of <i>Axin2, Dkk1, Fzd1, Lef1, TCF4</i> in limb skin of mutants at E16.5. **, P<0.01, compared to wild type controls. …”

DataSheet1_The Efficacy and Safety of Pulmonary Vasodilators in Pediatric Pulmonary Hypertension (PH): A Systematic Review and Meta-analysis.docx by Tingting Shu (353149)

“…In total, compared with the control group treatment, pulmonary vasodilators significantly decreased the mortality (p = 0.002), mean pulmonary artery pressure (mPAP, p = 0.02), and mechanical ventilation duration (p = 0.03), also improved the oxygenation index (OI, p = 0.01). …”

WNT enhances acinar progenitor activity through LRP6 signaling. by Lisa M. Arendt (204431)

“…(<b>I, J</b>) WNT1 expression increased acinar colonies, while reduced LRP6 expression diminished acinar colonies, when WNT1, EV, shscram, and shLRP6 expressing MECs were grown as mammospheres (<b>I</b>) or floating colonies (<b>J</b>) prior to plating on collagen (n = 5 patient samples; mean±s.e.m.). (<b>K</b>) TBX3 MCF10A cells demonstrated significantly increased expression of <i>WNT2B</i> and <i>WNT9A</i> compared with EV cells. …”

Genomic Analysis of the Function of the Transcription Factor <em>gata3</em> during Development of the Mammalian Inner Ear by Marta Milo (232638)

“…Expression levels estimated by this method correlated closely (p<0.0001) across a 10-fold range with those measured by quantitative RT-PCR for a sample of 61 different genes. …”

Table_1_Giant cell temporal arteritis: a clinicopathological study with emphasis on unnecessary biopsy.pdf by Hind M. Alkatan (11592654)

“…The mean diagnostic clinical score used in our study was higher (7.5 ± 2.33) in the GCA-positive group when compared to the other groups with statistical significance (mean of 4.85 ± 2.01 in patients with overall GCA-negative biopsies and 5.13 ± 2.10 in the group with atherosclerosis). …”

Knockdown of <i>Lmo4</i> in the BLC leads to enhanced freezing to the context and the cue. by Rajani Maiya (123315)

“…B) Immunohistochemical analyses revealed a robust decrease in LMO4 expression in GFP positive/infected cells (arrows point to infected neurons, right panel) from shLmo4-injected mice but not from shScr-injected mice (arrows point to infected neurons, left panel). …”

Elastic–Plastic Transformation of Polyelectrolyte Complex Hydrogels from Chitosan and Sodium Hyaluronate by Ran Shi (5915366)

“…They are elastic-like, independent of the strain rate at small strain, but exhibit plastic-like behavior above the yield point by showing a monotonous decrease of the stress. …”

Elastic–Plastic Transformation of Polyelectrolyte Complex Hydrogels from Chitosan and Sodium Hyaluronate by Ran Shi (5915366)

“…They are elastic-like, independent of the strain rate at small strain, but exhibit plastic-like behavior above the yield point by showing a monotonous decrease of the stress. …”

Elastic–Plastic Transformation of Polyelectrolyte Complex Hydrogels from Chitosan and Sodium Hyaluronate by Ran Shi (5915366)

“…They are elastic-like, independent of the strain rate at small strain, but exhibit plastic-like behavior above the yield point by showing a monotonous decrease of the stress. …”

Elastic–Plastic Transformation of Polyelectrolyte Complex Hydrogels from Chitosan and Sodium Hyaluronate by Ran Shi (5915366)

“…They are elastic-like, independent of the strain rate at small strain, but exhibit plastic-like behavior above the yield point by showing a monotonous decrease of the stress. …”

Elastic–Plastic Transformation of Polyelectrolyte Complex Hydrogels from Chitosan and Sodium Hyaluronate by Ran Shi (5915366)

“…They are elastic-like, independent of the strain rate at small strain, but exhibit plastic-like behavior above the yield point by showing a monotonous decrease of the stress. …”

Image1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.tif by Xiaozhen Huang (5858690)

“…All children demonstrated GH deficiency in growth hormone stimulation tests (mean peak GH value: 2.83 ± 2.46 ng/mL). Exome sequencing for the six patients and targeted gene sequencing for their family members revealed heterozygous variants in the GH1 gene, including Exon2-5del, c.334T>C, c.291 + 1G>A, c.291 + 2T>A, 1.5 kb deletion, and 1.7 kb deletion, with four variants being novel. …”

Table1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.docx by Xiaozhen Huang (5858690)

“…All children demonstrated GH deficiency in growth hormone stimulation tests (mean peak GH value: 2.83 ± 2.46 ng/mL). Exome sequencing for the six patients and targeted gene sequencing for their family members revealed heterozygous variants in the GH1 gene, including Exon2-5del, c.334T>C, c.291 + 1G>A, c.291 + 2T>A, 1.5 kb deletion, and 1.7 kb deletion, with four variants being novel. …”

The Effect of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) on Erectile Function: A Systematic Review and Meta-Analysis by Xiang Chen (10398)

“…A significant decrease in the IIFE-5 score was observed in the CP/CPPS group (pooled mean difference: −4.54, 95% CI: −5.11–−3.98; <i>P</i> < 0.01).…”

Multiple modes of modulation of PC simple spikes during light activation of ChR2 specifically expressed in GCs. Light activation of GCs results in inhibition and/or activation of P... by Wolfgang Kruse (619565)

“…Laser power was set to 10 mW, resulting in 2.5 mW in front of light fiber. (E) Mean increase of simple spike rate from 13 PCs showing excitation during light application and mean decrease of activity of 12 PCs showing inhibition during light application. …”

Associations between initial neutralizing antibody potency and rate of declining neutralization potency over time. by Lindsay Wieczorek (171734)

“…A positive fold change in Env sensitivity to a given NAb indicates increasing sensitivity (earlier PSV GM IC₅₀ > later PSV GM IC₅₀), while a negative fold indicates decreasing sensitivity over time (earlier PSV GM IC₅₀ < later PSV GM IC₅₀). …”