Connecting Protein Conformation and Dynamics with Ligand–Receptor Binding Using Three-Color Förster Resonance Energy Transfer Tracking by Mark Kastantin (1514023)

“…By controlling FN structure and dynamics through tuning surface chemistry, we found that as the conformational and translational dynamics of FN increased, the rate of binding, particularly to folded FN, and stability of the bound FN−α_vβ₃ complex decreased significantly. …”

Connecting Protein Conformation and Dynamics with Ligand–Receptor Binding Using Three-Color Förster Resonance Energy Transfer Tracking by Mark Kastantin (1514023)

“…By controlling FN structure and dynamics through tuning surface chemistry, we found that as the conformational and translational dynamics of FN increased, the rate of binding, particularly to folded FN, and stability of the bound FN−α_vβ₃ complex decreased significantly. …”

Histopathological scores and histopathologies of EAU mice. by Kayo Suzuki (166737)

“…Furthermore, these scores were further decreased when treated by inhibiting both Ang2 and VEGFA (i.e., anti-Ang2 antibody with anti-VEGFA antibody treatment group and anti-Ang2/VEGFA bispecific antibody treatment group) (P<0.01). …”

DataSheet1_Design parameters affecting mechanical failure and electrochemical degradation of ultrathin Li-ion pouch cells under repeated flexing.pdf by Kyungbae Kim (2158606)

“…We find that the observed mechanical failure modes are mainly dependent on the: 1) size and shape of the electrode composite materials, 2) configuration of the components within the cell (e.g., method of electrode folding, location of welded tabs), and 3) orientation of the long axis of the cell with respect to the bending axis. …”

Carbonyl Post-Translational Modification Associated with Early Onset Type 1 Diabetes Autoimmunity by Mei-Ling Yang (3625355)

Initial Mutations Direct Alternative Pathways of Protein Evolution by Merijn L. M. Salverda (228413)

“…We found that a combination of decreased enzymatic activity and lower folding cooperativity underlies negative sign epistasis in the clash between key mutations in the common and deviating lines (Gly238Ser and Arg164Ser, respectively). …”

Regular spiking neuron (sustained chopper) that exhibits accurate identification of envelope frequency from its spike trains. by Chris Scholes (3309477)

“…<b>e.</b> Period histograms, folded across stimulus periods, indicate reliable firing at certain phases of the stimulus cycle. …”

Responses of human pancreatic cancer cell lines to TRAIL (<i>A</i>) or to the combination of LBH589 and TRAIL (<i>B</i> and <i>C</i>). by John Kauh (365271)

“…In Capan-2 cells, LBH589 at 50 nM in combination with 12.5 ng/ml or 25 ng/ml is significantly more effectively than LBH589 or TRAIL alone in decreasing cell survival (<i>P</i><0.001). …”

Rotavirus replication, maturity and cytopathic effect of cultured extrahepatic biliary epithelia (EHBE). by Jiexiong Feng (345975)

“…Significantly less double-layered particles (DLPs, pointed by black arrows) and triple-layered particles (TLPs, pointed by black arrow heads with dash lines) existed in siNSP4 protected EHBE. siVP7 caused more synthesis of DLPs. …”

Longitudinal intravital fluorescence and svOCT imaging of radioresponse in tumor and vascular compartments <i>in vivo</i>. by Azusa Maeda (141179)

OroA inhibition of LPS-induced NF-κB activation in lung tissue of the rats. by Tzu-Ling Tseng (288836)

“…<p>LPS treatment (10 mg/kg, iv) significantly decreased cytosolic NF-κBp65 expression in lung tissue (Lane 2 in Fig. 6A) comparing to that by Sal (Saline) followed by Solv (Solvent) treatment (Lane 1 in Fig. 6A). …”

The effect of IL-17A on IκBζ - RGS4 signaling. by Hirotada Akiho (559455)

“…The effect of IL-17A or IL-1β with or without L-17RFcChimera or IL-17RC siRNA was examined (n = 4∼5). (<b>F</b>) The effect of IL-17A, IL-1β, or IL-4 on RGS 4 activity was assessed with or without SN50, a p65 translocation inhibitor, or IκBζ siRNA (n = 4∼5). …”

The Effect of India's Total Sanitation Campaign on Defecation Behaviors and Child Health in Rural Madhya Pradesh: A Cluster Randomized Controlled Trial by Sumeet R. Patil (621729)

“…The intervention increased percentage of households in a village with improved sanitation facilities as defined by the WHO/UNICEF Joint Monitoring Programme by an average of 19% (95% CI for difference: 12%–26%; group means: 22% control versus 41% intervention), decreased open defecation among adults by an average of 10% (95% CI for difference: 4%–15%; group means: 73% intervention versus 84% control). …”

SFN Inhibited invasion via sustained activation of ERK1/2. by Chunliu Li (284115)

“…Data were shown as means ± SD from three separate tests. (B) We seeded 1×10⁵ cells in a 24-well plate with cell inserts, the cells were added with SFN (20 µM) without or with PD98059 (25 µM) for 24 h to detect cell invasion. …”

Polyamines and biogenic amines levels during encystation. by Ghulam Jeelani (131311)

“…The average concentrations of each metabolite (nmol/1×10⁶ cells) at time intervals (0, 0.5, 2, 8, 24, 48 and 120 h) are shown. The enzymes are shown in yellow or blue in case where their transcript levels increased or decreased by >3 fold relative to time 0 h, respectively. …”

<i>Mll2^Gdf9</i> cKO females show impaired ovulation. by Claudia V. Andreu-Vieyra (243666)

“…<p>(A) Ovulation rates were significantly reduced in 3-wk-old superovulated <i>Mll2^Gdf9</i> cKO females (Student's <i>t</i> test, ** <i>p</i><0.01). Means ± S.E. are shown (five individual females were used; <i>n</i> = 5). …”

Disparities in COVID-19 primary vaccine series and boosters among Black, Hispanic, and Asian versus White residents of the same zip code. by Aaloke Mody (602279)

“…The dashed line represents equitable vaccine distribution between the racial/ethnic groups being compared. Points above the dashed line indicate that there was decreased vaccination in Black, Hispanic, or Asian residents compared to White residents (and vice versa). …”

Elephant seal dive behaviour responds consistently to changes in foraging success regardless of sex or ocean habitat by David Green (10157417)

Efficacy of R-LM113 and R-115 administered early after tumor implantation on the growth of HER2-LLC1 tumors. by Valerio Leoni (440542)

“…The mice decreased in number because of deaths caused by the primary tumor. …”

Table_1_Epidemiology of human papillomavirus infection in women from Xiamen, China, 2013 to 2023.DOCX by Xingmei Yao (11431322)

“…The five most prevent HR-HPV genotypes were HPV52 (4.0%), 58 (2.6%), 16 (2.5%), 51 (1.8%), and 39 (1.7%). …”