Endosome Ablation, Interference with Endosome to Plasma Membrane Fusion, and locking Rab11-Mediated Endosomal Recycling, all Inhibit tTG Externalization. by Evgeny A. Zemskov (223282)

“…Shown in (A–D) are representative of three independent experiments. Bars show means ± SEM, *p<0.05, **p<0.005. (E) Interference with GTPase activity of Rab11 decreases tTG externalization. …”

Data Sheet 1_Risk factors for adverse maternal and fetal outcomes in SLE patients: a systematic review and meta-analysis.pdf by Hang Liu (3694)

“…</p>Objective<p>The goal of this meta-analysis is to designate the risk factors for unfavorable maternal and fetal outcomes in SLE pregnancies by means of a systematic review of the literature and meta-analysis.…”

Isoflurane regulated cell death through miR-214. by Hailiang Yan (284342)

“…<p>(<b>A</b>) miR-214 specifically acted on Bax 3′UTR. (<b>B</b>) In SH-Sy5y cells, miR-214 inhibited total Bax (indicated by 2D2 antibody) expression. …”

Loss of <i>nowl</i> in the nervous system causes sleep fragmentation. by Gianna W. Maurer (6103637)

“…(H) Sleep pattern of <i>Neurofibromin-1</i> (<i>Nf1</i>) knockdown males under a 12-hour light/dark (white and black bars) cycle in 30-minute intervals shows effects on sleep compared to controls (<i>elav>+</i> and <i>Nf1-RNAi/+</i>) similar to animals lacking <i>nowl</i>, with decreased sleep mainly during the night. Graphs represent means with SEM (n = 32–92) of data pooled from one to three independent experiments. …”

Computational modeling of the bimodal distribution of RPs and altered parameters of the resting ion channels on the distribution of RPs. by Yuqin Yang (579353)

“…We computed the instantaneous conductances of Kir and K_D by Boltzmann equations, and the membrane potentials by the Hodgkin-Horowitz equation: <math><mrow><msub><mi>G</mi><mrow><mi>K</mi><mi>i</mi><mi>r</mi></mrow></msub><mo>=</mo><msub><mi>G</mi><mrow>max<mo>,</mo><mi>K</mi><mi>i</mi><mi>r</mi></mrow></msub><mo>/</mo><mrow><mo>(</mo><mrow><mn>1</mn><mo>+</mo>exp<mrow><mo>(</mo><mrow><mrow><mo>(</mo><mrow><msub><mi>V</mi><mi>m</mi></msub><mo>−</mo><msub><mi>V</mi><mrow><mn>0.5</mn></mrow></msub></mrow><mo>)</mo></mrow><mo>/</mo><mi>k</mi></mrow><mo>)</mo></mrow></mrow><mo>)</mo></mrow></mrow></math>; <math><mrow><msub><mi>G</mi><mrow><mi>K</mi><mi>D</mi></mrow></msub><mo>=</mo><msub><mi>G</mi><mrow>max<mo>,</mo><mi>K</mi><mi>D</mi></mrow></msub><mo>−</mo><msub><mi>G</mi><mrow>max<mo>,</mo><mi>K</mi><mi>D</mi></mrow></msub><mo>/</mo><mrow><mo>(</mo><mrow><mn>1</mn><mo>+</mo>exp<mrow><mo>(</mo><mrow><mrow><mo>(</mo><mrow><msub><mi>V</mi><mi>m</mi></msub><mo>−</mo><msub><mi>V</mi><mrow><mn>0.5</mn></mrow></msub></mrow><mo>)</mo></mrow><mo>/</mo><mi>k</mi></mrow><mo>)</mo></mrow></mrow><mo>)</mo></mrow></mrow></math>; <math><mrow><msub><mi>V</mi>m</msub><mo>=</mo><mrow><mo>(</mo><mrow><msub><mi>E</mi><mi>K</mi></msub><mo>*</mo><mrow><mo>(</mo><mrow><msub><mi>G</mi><mrow><mi>K</mi><mi>i</mi><mi>r</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mrow><mi>K</mi><mi>N</mi><mi>V</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mrow><mi>K</mi><mi>D</mi></mrow></msub></mrow><mo>)</mo></mrow><mo>+</mo><msub><mi>E</mi><mi>L</mi></msub><mo>*</mo><msub><mi>G</mi><mi>L</mi></msub></mrow><mo>)</mo></mrow><mo>/</mo><mrow><mo>(</mo><mrow><msub><mi>G</mi><mrow><mi>K</mi><mi>i</mi><mi>r</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mrow><mi>K</mi><mi>N</mi><mi>V</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mrow><mi>K</mi><mi>D</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mi>L</mi></msub></mrow><mo>)</mo></mrow></mrow></math>; Stable RPs were determined by programmed computation with MatLab software using up to 200 iterations after the initial parameters input (See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125266#pone.0125266.s001" target="_blank">S1 Dataset</a> for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125266#pone.0125266.g008" target="_blank">Fig 8<b><i>A—</i></b> 8<b><i>I</i></b></a>). …”

Graphical summary of research aim and key findings. by Berta Puig (344828)

“…Though not investigated here, p38 signaling may be reduced at early time points, contributing to delay to terminal disease (showed as p38?). …”

ROS is produced in both prion-infected and GDL-exposed COCS. by Uli S. Herrmann (124972)

“…DPI decreased superoxide-induced lucigenin conversion; <i>n</i> = 4 pools of 9 biological replicates. …”

Data_Sheet_1_How to “Start Small and Just Keep Moving Forward”: Mixed Methods Results From a Stepped-Wedge Trial to Support Evidence-Based Processes in Local Health Departments.pdf... by Rebekah R. Jacob (8638377)

“…LHD staff completed a quantitative survey at 4 time points measuring their EBDM skills, organizational supports, and evidence-based interventions. …”

The pathophysiological relevance of Rab26 to diabetes mellitus. by Ruijuan Zhuang (3938915)

“…In IPGTT experiment, the level of plasma insulin in mice was detected at 0 min, 15 min, 30 min, 60 min, and 120 min time points after transplantation for 5 d. (H) Blood glucose levels were measured from tail vein. …”

Table_1_How to “Start Small and Just Keep Moving Forward”: Mixed Methods Results From a Stepped-Wedge Trial to Support Evidence-Based Processes in Local Health Departments.DOCX by Rebekah R. Jacob (8638377)

“…LHD staff completed a quantitative survey at 4 time points measuring their EBDM skills, organizational supports, and evidence-based interventions. …”

Data_Sheet_2_How to “Start Small and Just Keep Moving Forward”: Mixed Methods Results From a Stepped-Wedge Trial to Support Evidence-Based Processes in Local Health Departments.pdf... by Rebekah R. Jacob (8638377)

“…LHD staff completed a quantitative survey at 4 time points measuring their EBDM skills, organizational supports, and evidence-based interventions. …”

In Vivo Response to Methotrexate Forecasts Outcome of Acute Lymphoblastic Leukemia and Has a Distinct Gene Expression Profile by Michael J Sorich (275350)

ACβ and PKA are both essential for parasite proliferation. by Avnish Patel (6393182)

“…Means from three replicates are plotted. Error bars, SD. …”

PGK1 K220 acetylation regulates glycolytic ATP production, glucose metabolism, and redox state of cells. by Shiwen Wang (132242)

“…(<b>B</b>) K220Q mutant PGK1 put-back cells display decreased levels of 3-PG and serine. Stable HEK293T cells were rinsed with 1 ml ice-cold PBS for less than 1 min and quenched by using 80% (v/v) pre-cold (-80°C) methanol, following the standard LC-MS method to determine intracellular levels of 3-PG and serine as described in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002243#pbio.1002243.s020" target="_blank">S1 Text</a>. …”

Optimizing replay intensity and resolution in aberration-compensated off-axis holograms by ambient humidity control by Henry Nebrensky (1229277)

“…When a scene is located in water but the image is replayed into air it is necessary to correct for the refractive index </p><p>difference by reconstructing the image with shorter wavelength illumination and changing the beam angle to satisfy the grating equation. However this means that the Bragg condition may no longer be satisfied during replay, reducing the diffraction efficiency and decreasing the SNR of the reconstructed images. …”

Neuronal loss of the <i>LZTR1</i> homolog <i>night owl</i> (<i>nowl)</i> reduces night-time sleep in <i>Drosophila</i>. by Gianna W. Maurer (6103637)

“…(B) Schematic of the <i>nowl</i> locus. The gene comprises 5′ and 3′ untranslated regions (light grey) and a multi-exon coding region (dark grey). …”

Running Opposes the Effects of Social Isolation on Synaptic Plasticity and Transmission in a Rat Model of Depression - Fig 1 by Marta Gómez-Galán (3232692)

“…Bar-graph data in C represent means ± s.e.m. GH:group-housed, SI: social-isolated, SI +R: social-isolated with access to a running wheel.…”

Data_Sheet_1_Small airways dysfunction in patients with systemic sclerosis and interstitial lung disease.docx by Panagiotis K. Panagopoulos (14113107)

Disentangling juxtacrine from paracrine signalling in dynamic tissue - Fig 6 by Hiroshi Momiji (3254958)

Deletion of the transmembrane helix promotes greater stability and biological activity. by Wei Yang (109917)

“…The P value of a two-tailed paired t test comparing NACC2-NTRK2(ex4:ex13) with NACC2-NTRK2-ΔTM was 0.0096, and is shown as ** = P ≤0.01. <b>(E)</b> Lysates prepared from cells expressing either NACC2-NTRK2 (left lanes) or NACC2-NTRK2-ΔTM (right lanes) and treated with cycloheximide for the indicated time points were examined by SDS-PAGE and immunoblotted for NTRK2 The left lanes show decreasing amounts of NACC2-NTRK2 in the presence of cycloheximide, while the right lanes reveal little or no change in NACC2-NTRK2-ΔTM under identical conditions. …”