Nrg1 activates hyphal growth in <i>S</i>. <i>japonicus</i> and is repressed by QS and the SAPK pathway. by Elisa Gómez-Gil (6785489)

“…(D) <i>nrg1</i>^<i>+</i> mRNA levels measured by qPCR from total RNA extracted from cell samples from wild type, <i>sty1</i>Δ and <i>atf1</i>Δ strains growing exponentially (time 0h), incubated for 3h in the presence of 0.2 μM CPT, or for 3h in the presence of 0.2 μM CPT plus 0.5 mM phenylethanol (PE). Results are shown as relative fold expression (mean ± SD) from three biological repeats. *, <i>P</i><0.05; **, <i>P</i><0.005; as calculated by unpaired Student´s <i>t</i> test. …”

MtNFP and MtLYK3, or AtCERK1 (co-)production in <i>Nicotiana</i> leaves induces defence-like responses. by Anna Pietraszewska-Bogiel (417871)

“…<i>Agrobacterium</i> transformants carrying either <i>MtNFP-3xFLAG</i> or <i>MtLYK3-3xFLAG</i> construct were co-infiltrated into <i>Nicotiana</i> leaves at five different time points (1–5). Macroscopic observation (left panel) and subsequent Evans blue staining (right panel) are depicted 42 hai (region 1), 39 hai (region 2), 36 hai (region 3), 33 hai (region 4) and 30 hai (region 5). …”

Parameters of VMR separated by light or dark periods run at 6 dpf. by Morgan Barnes (7876373)

“…There is a significant decrease in distance moved in the dark (p < 0.0001) and light periods (p < 0.0001), a decrease in velocity in the light (p < 0.001) and dark periods (p < 0.01), a decrease in activity state in the light (p < 0.01) and dark periods (p < 0.001) and an increase in distance to point in the light period (p < 0.01) in the 24 + fish. …”

Andro induced ROS-dependent autophagy while Taxi attenuated it. by Mazen Alzaharna (3737878)

“…(B, C & E) Results are represented as mean ± SD (n = 3). …”

The <i>Airn</i> CGI plays a major role in <i>Airn</i> transcription and function. by Martha V. Koerner (180097)

“…(D) ChIP for Ser5P/Ser2P RNAPII in <i>S12/+</i>, <i>S12/TDRΔ</i>-1A and <i>S12/CGIΔ</i>-1A d11 cells shows unaffected <i>Airn</i> initiation and elongation (except at <i>Airn</i>-end) in <i>TDRΔ</i> and a sharp RNAPII decrease in the <i>CGIΔ</i> allele. …”

Anti-HBV activity of CDM-3008 in primary cultured human hepatocytes. by Yutaka Furutani (5620139)

“…(E) HBsAg levels are shown as fold changes. HBsAg levels were significantly decrease with 10–100 μM CDM-3008. …”

The biphasic effect of emodepside on hum KCNMA1 currents. by Anna Crisford (803573)

“…Arrow indicates the time of emodepside application at <b>A</b>. 1nM <b>B</b>. 10nM and <b>C</b>. 100nM. Data points are the mean ± s.e.mean. 100nM emodepside had a biphasic effect on hum KCNMA1 currents eliciting a significant increase between 4 and 8 min application (p<0.05) and a significant decrease after 20 min application (p<0.001); two-way ANOVA with Bonferroni post-hoc tests.…”

Analysis of LRRK2 effect on DRD2 total protein level. by Mauro Rassu (4068670)

“…<b>(E)</b> SH-SY5Y-DRD2 transduced as in (A) were treated for different time points (15', 30', 45', 60') by puromycin, then cell lysates were prepared and analyzed by western blot. …”

LCAT is required for efficient asexual blood stage egress. by Abhinay Ramaprasad (521263)

“…Size of each datapoint represents the total number of egress events (abnormal + normal) counted in the video. <b>E)</b> Fold change in parasitaemia after 4 h invasion of mock- (-RAP) and RAP-treated (+RAP) LCAT:2loxPint schizonts under shaking and static conditions. …”

Evolution of mutation rates on simple fitness landscapes with different ruggedness. by Jeff Clune (53764)

“…The two colored points represent the mean fitness and mutation rate, both averaged over 50 runs where the mutation rate freely evolved, with initial rates of <i>U</i> = 1 (red) or 10⁻⁵ (blue). …”

Perinatal Exposure to a High-Fat Diet Is Associated with Reduced Hepatic Sympathetic Innervation in One-Year Old Male Japanese Macaques by Wilmon F. Grant (124839)

A neural network approach to modeling magnetohydrodynamic stagnation point Ree-Eyring flow over a convectively heated stretched surface by Mumtaz Khan (4370488)

Fast Segmentation of Stained Nuclei in Terabyte-Scale, Time Resolved 3D Microscopy Image Stacks by Johannes Stegmaier (285361)

“…We achieve an up to ten-fold decrease in processing times, allowing us to process large data sets while still providing reasonable segmentation results.…”

Effect of MEHP and PMA on the gene transcription of TSPO, PKCε, PPAR-α, PPAr-β/δ, and PPAR-γ. by Enrico Campioli (336888)

“…Cells were seeded for 24 h before treatment with MEHP (A–C) or PMA (D) and collected after the indicated time points (A) or after 4 days (B–D). qRT-PCR results are normalized to RPS18, expressed in terms of mean and S.E.M. calculated from 3 independent experiments, and presented as fold increase or decrease compared to control. …”

BCD cell redifferentiation involves MET. by Holger A. Russ (203401)

“…*p<0.05; **p<0.01. <b>E:</b> Immunostaining analysis of expanded islet cells at p6 following 8d treatment with RC shows a decrease in the number of vimentin-positive cells (mean±SD, based on counting >400 cells from each of 3 donors), and mutually-exclusive expression of vimentin and C-peptide. …”

Ursolic acid inhibits lymphocyte proliferation in vitro. by Rahul Checker (332303)

“…(G) Each bar represents percentage of apoptotic in each treatment group. Data points represent mean±S.E.M. from three replicates and three such experiments were carried out. …”

Slug regulates mammary epithelial cell differentiation pathways. by Mayssa Nassour (109073)

“…Arrows points to ER+ CK5- cells identified as luminal cells.…”

Modulation of gamma oscillations by speed in CA1 is rapid. by Caleb Kemere (452950)

“…The graph shows population data of normalized power of theta oscillation (7–9 Hz) vs. speed, both measured over 0.5 s windows. Points represent binned means with standard error; line shows linear regression of underlying data with 95% confidence intervals. …”

Chromatin mutant effects on mRNA expression dynamics during stress. by Assaf Weiner (147074)

“…Plotted are the fraction of (mutant×probe) effects with increased, or decreased, expression of the probe in question. This number represents the fraction of all entries in the 200 probe×202 mutant matrix (for each time point) with an absolute log2 change in RNA abundance of greater than 0.5. …”

A mechanistic mathematical model of HIV primary infection including VRC01. by Daniel B. Reeves (8407932)

“…Susceptible cells decrease by approximately 200 cells/<i>μ</i>L and reconstitute by viral set-point. …”